17,261 trials
Hepatitis B, Chronic
Primary: Number of Patients Experiencing Treatment Emergent Laboratory Test Abnormalities or Adverse Events. — 5 Participants
β-thalassemia Major
Primary: Percentage of Participants With Sustained Production of >=2.0 Grams Per Deciliter (g/dL) of Hemoglobin A (HbA) Containing βA-T87Q-globin (HbAT87Q) for the Six Months…
Non-small Cell Lung Cancer · Advanced Non-small Cell Lung Cancer · Recurrent Non-small Cell Lung Cancer
Primary: Antitumor Activity, as Measured by Tumor Response Rate of Hydroxychloroquine, Paclitaxel, Carboplatin, and Bevacizumab (for Eligible Patients) in Patients With Advanced…
Gastroparesis
Primary: Number of Participants With Improvement in Nausea — 29; 25 participants — p=0.43
Pain · Cancer · Colonic Diseases
Primary: Measurements of Visceral Pain, Using a 100-mm Visual Analog Scale (VAS) — 22.27; 18.93; 23.31; 22.22 mm — p=0.506
Lung Cancer
Primary: Progression Free Survival — 5.2; 14.5; 20.6; 8 month
Pain
Primary: Score on Faces Pain Scale - Revised — 4.7 units on a scale
Epilepsy
Primary: Mean Changes in Count of Generalized Spike-wave Discharges on 24-hour Ambulatory Electroencephalogram (EEG) From Visit 2 to Visit 6 — -4.55; -166.22; -203.12 discharges
Neural Tube Defects · Anemia · Leukemia, Myeloid
Primary: Full Donor Chimerism (FDC) — 6 Participants
Prostate Cancer
Primary: Percentage of Participants With Reduction in Acute Per-prostatic Rectal Ulcer Events Events From 90%+ to <70% (Particularly in the Anterior Rectum) — 13.6 percentage of…
Alopecia Areata
Primary: Change in SALT Score — 65.8; 24.8; 7.3 score on a scale
Nicotine Dependence
Primary: Time-to-lapse — 51.97; 56.44 Minutes
Rett Syndrome
Primary: Gait Velocity as Measured by GAITRite System — 58.6 cm/sec
Alopecia Areata
Primary: Total Number of Responders — 8 Participants
Neovascular Age-Related Macular Degeneration
Primary: Change From Baseline in Best Corrected Visual Acuity (BCVA) Measured by Early Treatment Diabetic Retinopathy Study (ETDRS) Letter Score at Week 12 — 5.2; 5.6; 5.4…