65,437 trials
COVID-19
Primary: Proportion of Participants With Serious Adverse Events — 0.83 Percentage of Participants
Diabetic Macular Edema
Primary: Incidence and Severity of Ocular Adverse Events in the Study Eye, With Severity Determined According to Adverse Event Severity Grading Scale — 219; 188; 197; 119…
Healthy
Primary: Pharmacokinetics (PK): Area Under the Concentration-time Curve, From Time 0 to the Last Observed Non-zero Concentration (AUC0-t) of Selpercatinib — 21600; 19100; 21000…
Prostate Cancer
Primary: Safety Endpoint: Number of Subjects in the Balloon and Control Groups With Rectal, Device or Procedure-related Grade > 1 AEs Within 6 Months of Procedure — 25; 18…
Premature Birth
Primary: Bland-Altman Analysis for Nellcor Pulse Oximeter — .151; .434 percentage of difference in mean
Thyroid; Deficiency · Quality of Life
Primary: ThyPRO Scale Scores (0-100, Higher Scores Indicating Worse Quality of Life) — 18.3; 19.9 score — p=<0.001
Cardiac Transplant Disorder
Primary: Hospital Choice — 4; 21; 34; 13 Participants
Pain Management
Primary: Pain Score — 5; 4.5; 4 units on a scale — p=0.668
Colorectal Cancer Screening
Primary: Number of Participants Up to Date on Colorectal Cancer Screening — 29; 31 Participants — p=<0.05
Cardiac Transplant Disorder
Primary: Hospital Choice — 64; 125; 163; 192 Participants
Multiple Myeloma
Primary: Progression Free Survival (PFS): Study C1071003 Cohort A Versus RWD COTA Cohort- Using Unweighted Analysis — NA; 4.70 Months — p=<.0001
Peripheral T Cell Lymphoma
Primary: Efficacy: Complete Response Rate — 11 Participants — p=.1
Hodgkin Lymphoma
Primary: Overall Response Rate (ORR) by BICR Based on IWG Criteria — 78.3; 64.2; 73.3 Percentage of participants
Cardiac Transplant Disorder
Primary: Hospital Choice — 33; 47; 23; 2 Participants
HIV
Primary: Number of Participants Requesting HIV Self-Testing — 130; 102 Participants