Phase 4 N=59 Use of Bevacizumab in Trabeculectomy Surgery
Glaucoma · Optic Neuropathy · Fibrosis
Primary: Intraocular Pressure — 13.9; 13.2 mm Hg — p=<0.05
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=48 Effects of Mitigation Treatments on Bruising of CCH-aaes Treatment of Buttock Cellulite
Edematous Fibrosclerotic Panniculopathy (EFP) · Cellulite
Primary: Number of Participants by Buttock at Each Level of Bruising on the Investigator Assessment of Bruising Severity Scale at Day 4 — 0; 0; 0; 0 Participants
Phase 4 N=276 A Study to Assess Safety of Canagliflozin and Metformin Hydrochloride Combination Given as a Supplement to Diet and Exercise to Improve Blood Sugar Level in Indian Adult Participants With Diabetes
Diabetes Mellitus
Primary: Percentage of Participants With Treatment Emergent Adverse Events (TEAEs) and Treatment Emergent Serious Adverse Events (TESAEs) — 41.6; 1.1 Percentage of participants
Phase 4 N=310 Zoledronic Acid for Osteoporotic Fracture Prevention (ZEST II)
Osteoporotic Fractures · Osteoporosis, Postmenopausal
Primary: Non-traumatic Incidental Fractures (Vertebral and Nonvertebral [Identified by X-ray, CT, MRI, VFA Imaging] Per Person-year) — 1.06093; 1.01563 Fractures per person-year…
Phase 4 N=1,278 Long Term Comparative Effectiveness of Once Weekly Semaglutide Versus Standard of Care in a Real World Adult US Population With Type 2 Diabetes - a Randomized Pragmatic Trial
Diabetes Mellitus, Type 2
Primary: Number of Participants With Glycosylated Haemoglobin (HbA1c) Less Than 7.0 Percentage (%) (53 Millimoles Per Mole [mmol/Mol]) at Year 1 (Yes/No) — 244; 226; 186; 236…
Phase 4 N=60 Study Evaluating Abuse Potential of Lyrica® in Healthy Non-Drug Dependent Recreational Opioid Users
Abuse Potential
Primary: Bipolar Visual Analog Scale (VAS) for "Drug Liking" Maximum Effect (Emax). — 54.30; 90.85; 72.53; 76.05 Score on a 100 mm scale — p=<0.0001
Phase 4 N=70 Oral Combined Hydrochlorothiazide/Lisinopril Versus Oral Nifedipine for Postpartum Hypertension
Hypertension in Pregnancy · Postpartum Preeclampsia
Primary: Number of Participants With Stage 2 Hypertension — 8; 12 Participants
Phase 4 N=54 Study Evaluating the Abuse Potential of NEURONTIN® in Healthy Non-drug Dependent, Recreational Opioid Users
Abuse Potential
Primary: Bipolar Visual Analog Scale (VAS) for "Drug Liking" Maximum Effect (Emax). — 54.89; 87.40; 57.89; 63.62 Score on a 100 mm scale — p=<.0001
Phase 4 N=450 MORDOR II Burkina Faso: Longitudinal Trial
Child Growth · Diversity of Microbiome · Child Mortality
Primary: Intestinal Microbial Diversity — 46.3; 49.5 index score
Phase 4 N=48 Selegiline to Zelapar Switch Study in Parkinson Disease Patients
Parkinson's Disease
Primary: Clinical Global Impression Scale — 21; 27 units on a scale
Phase 4 N=33 A Study to Evaluate IGSC 20% Biweekly Dosing in Treatment-Experienced Participants and Loading/Maintenance Dosing in Treatment-Naïve Participants With Primary Immunodeficiency
Primary Immunodeficiency
Primary: Treatment-experienced Cohort: AUC of IGSC 20% Administered Weekly Assessed as: Steady-State AUC of Total IgG Over a Regular Dosing Interval (τ) — 167045.65…
Phase 4 N=35 EXPEDITE: A Study of Remodulin Induction Followed by Orenitram Optimization to Treat Pulmonary Arterial Hypertension
Pulmonary Arterial Hypertension
Primary: Number of Subjects Achieving Oral Treprostinil Dose — 23 Participants
Phase 4 N=34 Bone Modeling Effects of Combined Anabolic/Antiresorptive Administration
Postmenopausal Osteoporosis
Primary: Cancellous Bone Formation Rate at Month 3 — 0.13; 0.01; 0.06 mm3/mm2/day
Phase 4 N=16 Neurotoxin and Physical Therapy
Cervical Dystonia
Primary: Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS) — 28; 20.1 total score on a scale
Phase 4 N=128 Efficacy and Patient Satisfaction of Miralax and Gatorade Versus Movi Prep
Colorectal Cancer
Primary: Bowel Prep Efficacy - Boston Bowel Preparation Scale (BBPS) — 1.79; 2.33; 2.06; 2.45 score on a scale — p=<0.0001