Phase 3 N=32 Intravenous Immunoglobulin (IVIG, Bioven) Efficacy and Safety in Chronic Primary Immune Thrombocytopenia (ITP) in Adults
Primary Immune Thrombocytopenia
Primary: Part (Percent) of Patients With Response (R) — 24 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=96 Contraception and Pregnancy in Diabetes Mellitus
Diabetes Mellitus, Type 1 · Contraception
Primary: Number of Women 'Prepared for Pregnancy\ — 3 participants
N/A N=511,285 Development and Validation of a Preoperative Frailty Index Using Health Administrative Data
Frail Elderly Syndrome · Surgery · Outcomes
Primary: Survival for One Year After Surgery — 396164; 0 Participants
Phase 3 N=57 Aspirin in Young Psychotic Patients
Psychosis · Acute Psychosis · Schizophrenia
Primary: Neurological Soft Signs — 6.96; 7.04 score on a scale — p=0.863
Phase 2 N=25 Brentuximab Vedotin in Patients With Relapsed or Refractory EBV-and CD30-positive Lymphomas
Relapsed or Refractory EBV-and CD30-positive Lymphomas
Primary: To Evaluate the Overall Response Rate (ORR) of Brentuximab Vedotin in EBV- and CD30-positive Lymphomas — 12 Participants
N/A N=158 Lyophilized Fecal Microbiota Transplantation for Recurrent Clostridioides Difficile Infection
Recurrent Clostridium Difficile Infection
Primary: No Recurrence of CDI-related Diarrhea at 13 Weeks From Last LYO-FMT — 106 participants
Phase 3 N=676 Сlinical Trial of Efficacy and Safety of Prospekta in the Treatment of Post-COVID-19 Asthenia.
Post-acute COVID-19 Syndrome
Primary: Change in the Mean FSS Score. — 46.4; 45.9; 29.9; 31.9 score on a scale — p=0.0016
N/A N=66 Study of Palliative Radiotherapy for Symptomatic Hepatocellular Carcinoma and Liver Metastases
Hepatocellular Carcinoma · Liver Metastases
Primary: Proportion of Patients Achieving Significant Improvement of Liver Cancer Pain/Discomfort — 16; 4 Participants — p=0.004
N/A N=189 Comparison of Perioperative Outcomes Between Energy Device During Laparoscopic Gastrectomy
Postoperative Inflammation · Postoperative Fever
Primary: Postoperative 2nd Day CRP — 11.12; 9.03; 12.67 mg/dL
Phase 1 N=140 Safety and Immunogenicity Study of GSK's Clostridium Difficile Vaccine 2904545A When Administered in Healthy Adults Aged 18-45 Years and 50-70 Years
Clostridium Infections
Primary: Number of Subjects With Any and Grade 3 Solicited Local Symptoms, After Each Vaccine Dose — 0; 0; 0; 8 Participants
Phase 3 N=300 Study of Mirogabalin for Central Neuropathic Pain
Central Neuropathic Pain
Primary: Change From Baseline in the Weekly Average Daily Pain Score (ADPS) at Week 14 Following Administration With Mirogabalin or Placebo — -1.23; -0.52 units on a scale…
Phase 4 N=201 A Study to Evaluate the Efficacy and Safety of Safinamide Mesilate as Add-on Therapy to Levodopa in Parkinson's Disease Participants With Motor Fluctuation in South Korea
Parkinson Disease
Primary: Change From Baseline in Daily "OFF" Time at Week 18 — -0.8 hours — p=<0.001
Phase 1 N=12 A Study to Understand the Effect of Itraconazole on the Levels of a Study Medicine Called ARV-471 in Healthy Adults
Healthy
Primary: Area Under the Plasma Concentration-Time Curve From Time 0 Extrapolated to Infinity (AUCinf) of ARV-471 — 18960; 32020 nanogram*hour per milliliter (ng*hr/mL)
N/A N=1,520 Registry For Temsirolimus, Sunitinib, And Axitinib Treated Patients With Metastatic Renal Cell Carcinoma (mRCC), Mantle Cell Lymphoma (MCL), And Gastro-Intestinal Stroma Tumor (GIST) [STAR-TOR]
Carcinoma, Renal Cell, Advanced · Lymphoma, Mantle-Cell · Gastrointestinal Stroma Tumors
Primary: Overall Survival (OS) — 11.04; 25.36; 18.37; 15.11 Months
Phase 1 N=28 Green (Sustainable) VENTOLIN - Pharmacokinetics (PK) Study in Healthy Participants
Asthma
Primary: Area Under the Plasma Concentration-time Curve up to 30 Minutes Post-dose (AUC (0-30 Min)) of Salbutamol — 0.622; 0.536 Hour*nanogram/milliliter (h*ng/mL)