Phase 2 N=152 Study to Assess the Efficacy of VLY-686 in Relieving Symptoms of Gastroparesis
Gastroparesis
Primary: Change From Baseline in Average Nausea Severity — -1.25; -0.73 score on a scale (change from baseline) — p=.0099
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 1 N=24 A Study of TAK-227 in Healthy Adults
Healthy Volunteers
Primary: Cmax: Maximum Observed Plasma Concentration for TAK-227 — 464.4; 190.9; 370.0 nanogram per milliliter (ng/mL)
Phase 3 N=368 Safety and Efficacy Study of the Simultaneous Treatment of Upper Facial Lines (Horizontal Forehead Lines, Glabellar Frown Lines and Crows Feet) in Subjects With Moderate to Severe Upper Facial Lines
Moderate to Severe Upper Facial Lines (Horizontal Forehead Lines, Glabellar Frown Lines, and Lateral Canthal Lines)
Primary: Main Period: Percentage of Glabellar Frown Line (GFL) Responders at Day 30 — 0; 49.5 percentage of subjects — p=<0.0001
Phase 4 N=314 Effects of Microplegia on Transfusion Rates After Cardiac Surgery
Aortic Valve Disease · Mitral Valve Disease
Primary: Intraoperative and Postoperative Transfusions — 2.43; 2.97; 4.42; 3.50 units of blood per participant — p=0.354
N/A N=82 Auricular Acupuncture in the Treatment of Obesity
Obesity
Primary: Weight Change — 7; 15.1 pounds
N/A N=120 DigiVis: Self-testing Vision App for Telephone Consultations
Visual Impairment · Amblyopia Suspect
Primary: Mean Bias Between the Difference Between DigiVis and Standard Visual Assessment Compared to the Mean of DigiVis and Standard Visual Assessment — 0.112; 0.100 logMAR
Phase 1 N=24 Pharmacokinetic Evaluation of Intranasal Nalmefene Using Three Dosing Regimens
Opioid Overdose
Primary: Maximum Plasma Concentration (Cmax) — 10.8; 18.9; 22.2 ng/ml
Phase 1 N=28 A Study of B244 Delivered as a Topical Spray to Assess Safety in Pediatric Subjects With Atopic Dermatitis
Eczema · Atopic Dermatitis
Primary: Number of Participants With Treatment-emergent Adverse Events (TEAEs)as Assessed by CTCAE v4.0 — 11 Participants
N/A N=15 A Study of the Quality of Life in Adults With Crohn's Disease With Complex Perianal Fistulas
Crohn Disease · Rectal Fistula
Primary: Meta-Scores of the 12-Item Short Form Health Survey (SF-12) Questionnaire's Physical Component Score [PCS-12] — 45.36 score on a scale
N/A N=57 Effect of Guided Imagery for Radiotherapy-Related Distress in Patients With Head and Neck Cancer
Head and Neck Cancer
Primary: The Desire for Patients to Want to Use Guided Imagery While Undergoing Radiotherapy: [Feasibility] — 19; 25 Participants
N/A N=224 Nudge to Drive Transitions of Care
Preeclampsia · Preeclampsia Severe · Gestational Hypertension
Primary: Number of Patients With Documented Counseling on Transitions of Care — 38; 28 Participants
N/A N=120 Carillon Mitral Contour System® for Reducing Functional Mitral Regurgitation
Mitral Valve Insufficiency · Heart Failure
Primary: Change in Baseline Regurgitant Volume Associated With the Carillon Device Relative to the Control Population at 12 Months — -7.07; 3.32 ml/beat
Early Phase 1 N=20 The Influence of Testosterone on Experimental Pain Perception
Acute Pain
Primary: Pain Tolerance — 224.20500; 224.92615 Seconds
N/A N=33 Role of the Protein Matrix in the Anabolic Response to a Ground Beef Patty as Opposed to the Impossible (Vegi-) Burger
Protein Metabolism
Primary: Postprandial Plasma Essential Amino Acid Concentration Incremental Area-under-the-curve [ Time Frame: 360 Minutes] — 117896; 75098; 94058 micromoles per liter per minute
N/A N=6 Nurtured Heart Parenting Intervention for Child Behavioural Problems
Parent-Child Relations · Child Behavior Problem
Primary: Parent-reported Child Behavioural Problems — 1 participants