12,372 trials
Status Epilepticus
Primary: Number of Subjects With Termination of Seizures at ED Arrival With no Rescue Therapy Given — 329; 282 participants — p=<0.001
Type 1 Diabetes
Primary: Number of Participants With a 2-step or Greater Increase in Early Treatment Diabetic Retinopathy Study (ETDRS) Severity Scale. — 178; 217 Participants — p=0.0508
Autism
Primary: Number of Participants With the Given Clinical Global Impression Scale - Improvement (CGI-I) Score — 5; 5; 10 participants
Refractory Reflux Esophagitis
Primary: Percentage of Participants With Healing Demonstrated Via Upper Gastrointestinal Endoscopy (Modified Los Angeles Classification: Grade N) — 58.8; 78.4; 77.0 Percentage of…
Atherosclerosis · Coronary Artery Disease
Primary: Major Adverse Cardiac Events (MACE) (Percentage of Participants With an Event) — 0.0 percentage of participants — p=<0.0001
Human Immunodeficiency Virus
Primary: Number of Participants Who Achieved HIV Ribonucleic Acid (RNA) <50 Copies/mL at Week 48 — 44; 43; 11; 16 Participants
Chronic Obstructive Pulmonary Disease
Primary: Trough Forced Expiratory Volume in 1 Second (FEV1) at 12 Weeks — 1.408; 1.301 Liters
Venous Thromboembolism
Primary: Percentage of Participants With Symptomatic Recurrent Venous Thromboembolism [VTE] (i.e. the Composite of Recurrent Deep Vein Thrombosis [DVT] or Fatal or Non-fatal…
Breast Cancer
Primary: Percent Change in Lumbar Spine (L2-L4) BMD After 12 Months of Letrozole Therapy — 2.680; -3.314 Percent Change
Prostate Cancer
Primary: Change From Baseline in Prostate Size Based on Trans Rectal Ultra Sound (TRUS) at Week 12 (Full Analysis Set) — -37.2; -39.0 milliliter — p=0.36
Bipolar Disorder · Bipolar Depression
Primary: The Mean Change From Baseline to Week 2 in the Montgomery Asberg Depression Rating Scale (MADRS) Total Score — -13.1; -6.6 score on a scale
Essential Hypertension
Primary: Change in Seated Diastolic Blood Pressure (SeDBP). — -22.5; -22.5; -23.0; -23.9 mm HG — p=0.0071
Coronary Artery Disease
Primary: Maximum Observed Everolimus Blood Concentration (Cmax) — 0.71; 0.67; 0.91 ng/mL
Acne Vulgaris
Primary: Percent Change From Baseline in Total Lesion Count — -74.1; -56.8 percent of change
Influenza
Primary: The Geometric Mean (GM) Number of Influenza-specific CD4 T-cells Per Million CD4+ T-cells Identified After in Vitro Stimulation With Pooled Vaccine Strains Which Are…