17,261 trials
Recurrent Thyroid Gland Carcinoma · Stage I Thyroid Gland Papillary Carcinoma · Stage II Thyroid Gland Papillary Carcinoma
Primary: Objective Response Rate (ORR) — 1 Participants
Clostridium Difficile Associated Disease
Primary: Percentage of Participants Reporting Prespecified Local Reactions Within 7 Days After Dose 1 (50- to 64-Year Age Cohort) — 16.7; 16.7; 50.0; 16.7 Percentage of…
Acute Myeloid Leukemia
Primary: Recommended Phase II Dose (RP2D) of Ribavirin When Given in Combination With Low-dose Ara-C — 1400; 10 mg
Orthostatic Intolerance
Primary: Orthostatic Tolerance — 634 mmHg*min
Chronic Obstructive Pulmonary Disease
Primary: Mean Rate of Moderate or Severe Acute Exacerbations of Chronic Obstructive Pulmonary Disease (AECOPD) — 0.78; 0.71 AECOPD events/year — p=0.645
Diabetes Mellitus, Type I
Primary: Insulin Independence With Both an HbA1c ≤ 6.5% and no Severe Hypoglycemic Events at 1 Year After the First Islet Transplant or a Reduction in HbA1c of at Least 1 Point…
Schizophrenia
Primary: Change in MATRICS Consensus Cognitive Battery Composite Score Change — 1.3; 2.3; -0.2 units on a scale
Ischemic Stroke
Primary: Maximum Expiratory Pressure — 104.31 cm H2O (pressure measurement) — p=.001
B-cell Adult Acute Lymphoblastic Leukemia · B-cell Childhood Acute Lymphoblastic Leukemia · Recurrent Adult Acute Lymphoblastic Leukemia
Primary: Second Complete Remission Rate at the End of Block 1 Reinduction Chemotherapy — 72.2; 63 Percentage of participants
Obsessive-Compulsive Disorder
Primary: Clinical Improvement (Yale-Brown Obsessive Compulsive Scale/Y-BOCS) — 36; 9 percentage of participants — p=<0.05
T2 Diabetes and Fatty Liver Disease (Non-alcoholic Origin)
Primary: Change From Baseline to Week 12 in % Liver Fat as Assessed by MRI (Comparison Versus Placebo) — 0.79; 0.97 ratio of % liver fat — p=0.046
Hypogonadism
Primary: Change in Lean Body Mass — -2000; -1500 grams
Anaplastic Large Cell Lymphoma · Cutaneous B-cell Non-Hodgkin Lymphoma · Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue
Primary: Progression-free Survival — 56 percentage of participants
Blood Cancer · Leukemia · Graft Versus Host Disease
Primary: Engraftment of Haploidentical CD34+ Selected Blood Stem Cells in Older Patients or Those With Medical Co-morbidities Following Total Lymphoid Irradiation and…
Influenza
Primary: Number of Subjects Seroconverted for HI Antibodies Against Flu A/CAL/7/09 H1N1 Strain — 63; 58; 61; 96 Subjects