17,261 trials
Pelvic Inflammatory Disease
Primary: Clearance of Anaerobic Organisms From the Endometrium — 14; 18; 7; 1 participants — p=0.046
Liver Cirrhosis · Hepatic Cirrhosis · Portal Hypertension
Primary: Hepatic Venous Pressure Gradient (HVPG) — 15.2; 8.05; 20.62; 14.1 mmHg — p=0.257
Autosomal Dominant Hypocalcemia (ADH)
Primary: Number of Participants With Treatment Emergent Adverse Events (TEAEs) and Treatment Emergent Serious Adverse Events (TESAEs) — 3; 1 participants
Indolent Non-Hodgkin's Lymphoma · Follicular Lymphoma · Small Lymphocytic Lymphoma
Primary: Overall Safety of Idelalisib — 88.9; 27.8; 55.6; 83.3 percentage of participants
Mouth Neoplasms
Primary: Change in IL-2 Levels — 1.8; 4.0; 7.9; 2.1 pg/100 gm protein — p=<0.05
Anemia
Primary: Median Change From Baseline in Hemoglobin Levels to End of Initial Treatment Under Constant Dosing Regimen — -0.29; -0.92; -0.04; -0.46 g/dL
Anemia
Primary: Median Change From Baseline in Hemoglobin Levels to End of Initial Treatment Under Constant Dosing Regimen — -0.80; -0.60; -0.29; 0.02 gram per deciliter
Sickle Cell Disease
Primary: Change in Frequency of Vaso-occlusive Pain Events, Before and After Treatment With Simvastatin — 0.2365; 0.1311 proportion of pain days — p=0.005
Malignant Brain Tumors
Primary: Number of Participants With Objective Response — 2; 2; 4; 19 Participants
Fallopian Tube Cancer · Ovarian Cancer · Primary Peritoneal Cavity Cancer
Primary: Progression Free Survival (PFS) — 3.5; 3.0 months — p=0.49
Carcinoma, Adenoid Cystic · Head and Neck Neoplasms
Primary: Tumor Progression — 0; 0; 7; 4 Participants
Tourettes Syndrome · Tic
Primary: Improvement in Tic Severity — 24.3; 21.3 units on a scale
Post Menopausal Osteoporosis
Primary: Percent Change From Baseline in Bone Mineral Density (BMD) of Lumbar Spine at 6 Months — 1.87; 2.33; 2.95; 5.80 Percent change — p=0.0066
Non-Small Cell Lung Cancer
Primary: Percentage of Participants With Objective Response According to Modified Response Evaluation Criteria in Solid Tumors (RECIST) — 32; 21; 23 percentage of participants
Refractory Brain Tumors
Primary: Number of Participants With Objective Response — 4; 5; 12; 10 Participants