17,261 trials
Chronic Heart Failure
Primary: Percentage of Participants With Chronic Heart Failure (CHF) Who Develop Anti-serelaxin Antibodies at Any Time Following Repeat Administration of IV Continuous Infusions…
Painful Diabetic Neuropathy
Primary: Change From Baseline to Week 12 in the Average Daily Pain NPRS (Numeric Pain Rating Scale) Score; mLOCF Imputation — -1.9; -2.4; -1.5; -2.7 units on a scale — p=0.168
Leukemia
Primary: Participant Best Response Assessed Using Response Evaluation Criteria In Solid Tumors (RECIST) Version 1.1 — 0; 0; 1; 1 participants
Alcohol Dependence
Primary: Alcohol Craving in Response to the Alcohol Cue Script — 11.6932; 14.6126 Units on a scale
Breast Neoplasms
Primary: Feasibility of PBI Directed External Radiotherapy as Measured by Percentage of Participants Achieving a Dosimetrically Satisfactory Treatment Plan — 100; 100 percentage…
Chronic Lymphocytic Leukemia
Primary: Number of Participants Who Received Obinutuzumab and Chlorambucil in the Study — 19; 19 participants
Adenocarcinoma of the Pancreas · Recurrent Pancreatic Cancer · Stage III Pancreatic Cancer
Primary: Overall Survival (OS) — 7.3 months
Adenoid Cystic Carcinoma
Primary: Objective Response Rate (ORR) — 0 percentage of participants
Rheumatoid Arthritis
Primary: American College of Rheumatology 20% (ACR20) Response Rate at Week 12 — 45.1; 58.0; 60.0; 54.0 percentage of participants
Relapsed or Refractory Mantle Cell Lymphoma (MCL)
Primary: Objective Response Rate (CR + PR) — 46.7 percentage of participants
Gout · Moderate Renal Impairment
Primary: Percentage of Participants With Serum Urate <5.0 mg/dL at Month 3 — 0; 13.5; 35.9; 40.5 percentage of participants — p=<0.001
Cerebral Amyloid Angiopathy
Primary: Change From Baseline to Day 2 in Cerebrovascular Reactivity as Measured by the Slope (Amplitude Over Time to Peak) From Visual Task-evoked Functional Magnetic Resonance…
Rectal Cancer
Primary: Percentage of Pathologic Response Rate (pCR) With 95% Confidence Interval. — 26.6; 26.7 percentage of participants
Dengue · Dengue Fever · Dengue Hemorrhagic Fever
Primary: Percentage of Participants With Antibody Titer ≥ 10 1/Dil Against Each Dengue Virus Serotype Before and After Each Vaccination With Either Tetravalent Dengue Vaccine or…
Metastatic Breast Cancer
Primary: Objective Response Rate (ORR) — 30.8; 31.0; 55.6 percentage of participants