Phase 4 N=500 Assessment of Safety Profile of MVA-BN Vaccine in the PALM-007 Study in DRC
Monkeypox
Primary: Frequency of SAEs After First Dose of MVA-BN Vaccine — 0 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=23 Characterizing Late-season Influenza Vaccine Responses to Compare the 2023 and 2024 Vaccine Formulations
Influenza A
Primary: Magnitude of Antibody Response After the Late-season 2023 Vaccine — 6; 6; 74; 27 HAI Titer
Phase 4 N=155 Baseline Oral Health Study: UnCoVer the Connections to General Health
Cardiovascular Diseases · Diabetes Type 2
Primary: Impact of Treatment on Change in Oral Health Measures — 0.186; 0.190 millimeters (probing depth difference) — p=0.957
Phase 4 N=35 Counseling Among Gender Diverse Adolescents Who Use Depot Medroxyprogesterone
Gender Dysphoria, Adolescent
Primary: Number of Participants Satisfied With Self-Administered DMPA at Initiation — 17 Participants
Phase 4 N=33 Study of B/F/TAF in Participants Switching From CAB + RPV to B/F/TAF for HIV-1 Infection (EMPOWER)
HIV-1-infection
Primary: Percentage of Participants Experiencing Treatment Emergent Grade 3 or 4 Drug-related Adverse Events Through Week 12 (Co-Primary Endpoint) — 0 percentage of participants
Phase 4 N=154 Intubation Conditions Achieved With Rapid Co-administration of Rocuronium and Propofol Versus Classical Induction
Anesthesia
Primary: The Total Time Between Laryngoscope Insertion Into Mouth and the Onset of Ventilation After Tracheal Intubation — 30.0; 33.0 seconds
Phase 4 N=78 Effect of Vitamin D as Adjuvant Therapy in Preterm Infants With Neonatal Sepsis
Neonatal Sepsis · Preterm Infants
Primary: Change From Baseline in the Modified Töllner Sepsis Scoring System After 7 Days — 7; 7; 8; 9 Score — p=<0.001
Phase 4 N=29 Lemborexant Shift Work Treatment Study
Shift-Work Related Sleep Disturbance
Primary: Daytime Total Sleep Time in Minutes Per Day Collected From the Consensus Sleep Diary — 362.7; 365.3 Minutes per day — p=0.884
Phase 4 N=1,000 A Study to Investigate Cardiac Troponin Levels After mRNA-1273.712 Vaccine in Participants 12 Through 30 Years of Age
Healthy Volunteers
Primary: Number of Participants With Elevated Cardiac Troponin I (cTnI) at Day 4 or Day 32 (3 Days After Injection 1 or Injection 2) — 1; 0 Participants
Phase 4 N=20 Anti-CGRP for Inflammation and Pain Modulation in Small Fiber Neuropathy/Fibromyalgia
Trigeminal Neuralgia · Glossopharyngeal Neuralgia
Primary: Change in Pain Score — -0.6224; -1.005; -0.8102; -1.079 score on a scale
Phase 4 N=50 BLOCKade of Calcium Channels and Beta Adrenergic Receptors for the Treatment of Hypertension in HFpEF
Heart Failure With Preserved Ejection Fraction · Hypertension
Primary: Difference in Home Systolic Blood Pressure — 130.7; 134.5 mm Hg — p=0.017
Phase 4 N=93 The Ultrasound Guided Pericapsular Nerve Group and Anterior Quadratus Lumborum Blocks in Hip Replacement Surgeries
Post Operative Analgesia
Primary: The Total Amount of Morphine Consumption — 6.0; 8.0; 12.0 mg of IV morphine — p=0.035
Phase 4 N=5,052 Duration of Dual Anti-Platelet Therapy (DUAL-ACS)
Acute Coronary Syndrome · Coronary Artery Disease
Primary: Time-to-event: All-cause Mortality — 447.337; 445.196 days
Phase 4 N=33 Efficacy of Intercostal CryoAnalgesia in Robotic Lung Resection
Pain, Postoperative · Lung Diseases
Primary: Change in Visual Analogue Scale (VAS) Pain Score — 4.94; 7.50; 4.57; 6.25 scores on a scale
Phase 4 N=13 Anti-Diabetic Medications to Fight PD and LBD
Lewy Body Dementia · Parkinson Disease
Primary: Change in Movement Disorder Society- Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Score — 3.0; -2.5; -2.5; 1.5 score on a scale — p=0.008