Clinical Trial Search

Primary: Number of Participants With Adverse Events (AEs) — 6 Participants

Primary: The Percentage of Participants With Adverse Events (AEs), Coded to the Medical Dictionary for Regulatory Activities - System Organ Class Eye Disorders, as Determined by…

Primary: Mean Change From Baseline in Corneometry Value at Each Post-treatment Timepoint — 23.1; 23.3; 7.8; 0.1 Arbitrary units — p=<0.0001

Primary: No-Show Rate — 11.9; 11.1; 10.5; 12.1 percentage of appointments no showed — p=0.145

Primary: Presence of Post Operative Cognitive Dysfunction (POCD) — 15 Participants

Primary: Proportion of Transdermal Derived Glomerular Filtration Rate (tGFR) Values Within 30% of the nGFR Plasma-derived Indexed Glomerular Filtration Rate (nGFR) Values — 0.96…

Primary: Overall Response Rate (ORR) Per Independent Review Committee (IRC) in Main Cohort — 54.5 Percentage of participants

Primary: Renal Failure Event Defined as Greater Than or Equal to 40% Decline in Estimated Glomerular Filtration Rate (eGFR) or Occurrence of End Stage Renal Disease (ESRD) — 9.7…

Primary: Percentage of Participants With Local Reactions Within 7 Days After Administration of Study Intervention — 0.0; 0.0; 0.0; 2.3 Percentage of participants

Primary: Correlation Between the Change From Baseline in VMR Measured With FVA System at Month 3 and the Change From Baseline in the CFS at Month 3. — -0.7028 Spearman's…

Primary: Change From Baseline at Week 12 in Ocular Pain Severity Visual Analog Scale (VAS) — -23.7; -21.7; -25.3 Scores on a scale — p=0.930

Primary: Mean Change in Pupil Diameter — 3.73; 6.46 millimeters

Primary: Serious Adverse Events — 1; 0; 1; 0 Participants

Primary: Completion of TBI Treatment — 45 Participants

Primary: Change From Baseline in Parent Mental Health and Well-being (Parent Report) — .7442; .7523; .6484; .5571 score on a scale — p=.548