Phase 4 N=70 Platelet-rich Plasma vs. Hyaluronic Acid for Glenohumeral Osteoarthritis
Osteoarthritis · Shoulder Pain
Primary: Shoulder Pain and Disability Index (SPADI) Score — 50.3; 49 score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=5 Management of Acute Pulmonary Hypertensive Crisis in Children With Known Pulmonary Arterial Hypertension
Pulmonary Arterial Hypertension
Primary: Change in Systemic Vascular Resistance Index (SVRI) to Pulmonary Vascular Resistance Index (PVRI) Ratio (Rp:Rs Ratio) — 0.8; 0.75; 0.61; 0.73 Rp:Rs ratio — p=0.9
Phase 4 N=112 Liposomal Bupivacaine vs Dexamethasone ISB
Shoulder Pain
Primary: Numerical Rating Scale (NRS) Pain at Rest Over 72 Hours — 2.4; 3.4 score on a scale
Phase 4 N=20 Aczone Gel 7.5% in the Treatment of Acne Vulgaris in Patients With Skin of Color
Acne Vulgaris
Primary: Mean Change From Baseline to Week 12 in Global Acne Assessment Score (GAAS) — -0.86 score on a scale
Phase 4 N=180 Minimal Opioid Use After Total Hip Replacement (THR)
Osteoarthritis, Hip
Primary: Opioid Use — 30; 22.5; 15 Oral Morphine Equivalent (mg)
Phase 4 N=160 Multimodal Uterotonics at the Time of Cesarean Section in Laboring Patients
Uterine Atony With Hemorrhage
Primary: Number of Participants With Need for Additional Uterotonics (Methylergonovine, Carboprost, Misoprostol) — 80; 80 Participants
Phase 4 N=79 Liposomal Bupivacaine Interscalene Blocks for Rotator Cuff Repair
Acute Pain
Primary: Total Intraoperative Opioids Used — .1; .1; 30; 30 mg
Phase 4 N=20 Study of Pegloticase in Participants With Uncontrolled Gout Who Have Had a Kidney Transplant
Uncontrolled Gout · Kidney Transplant
Primary: Percentage of Serum Uric Acid (sUA) < 6 mg/dL Responders During Month 6 — 88.9 percentage of participants
Phase 4 N=100 Syphilis Self-testing to Expand Test Uptake Among Men Who Have Sex With Men (SST)
Syphilis
Primary: Syphilis Tests Undertaken — 29; 37 Participants
Phase 4 N=171 Study Assessing Deep Molecular Response in Adult Patients With CML in Chronic Phase Treated With Nilotinib Firstline.
Chronic Myeloid Leukemia
Primary: Percentage of Participants With Deep Molecular Response MR4.5 at 24 Months of Study Treatment — 35.3 Percentage of participants
Phase 4 N=52 Dupilumab Skin Barrier Function Study in Atopic Dermatitis
Atopic Dermatitis
Primary: Percent Change From Baseline in Transepidermal Water Loss After 5 Skin Tape Stripping (STS) on Lesional Skin (LS) in AD Patients at Week 16 — -54.6 percent change…
Phase 4 N=62 Standard-dose Versus High-dose Flu Vaccine in Solid Organ Transplant.
Influenza, Human · Transplantation Infection
Primary: Number of Patients With Local Site Reactions — 2; 2 Participants
Phase 4 N=97 Study of Pharmacogenomic-Guided Tacrolimus Dosing and Monitoring in Kidney Transplant Recipients
Renal Transplant
Primary: Proportion of Patients Reaching Target Tacrolimus Levels (8-10 ng/mL) on Day 3 After Kidney Transplantation — 0.2; 0.14 proportion of participants — p=0.58
Phase 4 N=158 XEN-45 Gel Stent Versus Trabeculectomy in Glaucoma: Gold-Standard Pathway Study (GPS)
Glaucoma
Primary: Percentage of Participants Achieving at Least 20% Intraocular Pressure (IOP) Reduction (Improvement) From Baseline at Month 12 With Prespecified Caveats — 62.1; 68.2…
Phase 4 N=190 Effects of a Surgical Site Injection on Pain Scores and Narcotic Use After Orthopaedic Trauma Surgery
Pertrochanteric Fracture
Primary: Amount (mg) of Narcotics (Oral Morphine mg Equivalents) Used — 16; 10 morphine milligram equivalents (MME)