65,437 trials
Marijuana Smoking
Primary: Validity of the Marijuana Purchase Task (MPT) — 63 percentage of participants — p=.00000004
Sleep Disturbance · Craving · Cortisol; Hypersecretion
Primary: Change in Total Sleep Time as Measured by Actigraphy and Sleep Logs Relative to Baseline Over the Course of 7 Days of Treatment With Suvorexant in Substance Use Disorder…
Contraception · Abortion, Therapeutic
Primary: Intention-to-treat Analysis of Etonogestrel Implant Use — 40; 19; 3; 3 Participants
Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM)
Primary: Percentage of Participants With Cardiac Fixation at the Radionuclide Bone Scintigraphy and/or Single Photon Emission Computed Tomography (SPECT): FAS1 — 32.0 Percentage…
Diabetes, Gestational
Primary: Change in Self-reported Physical Activity (Assessed by Pregnancy Physical Activity Questionnaire) From Baseline to Follow-up — 0.22; -0.70 MET hours per week
Immunocompromised · Immunosuppressed · Covid-19
Primary: Incidence Rate of Breakthrough Cases of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection — 0.89; 0.34 Events per 100 person-years
Asthma
Primary: Number of Symptom-Free Days in the Prior 2 Weeks — 9.5; 10.1 days
Pregnancy · Contraception
Primary: Part 1: Serum Medroxyprogesterone Acetate (MPA) Concentration at Day 1 — 0.36; 0.67 nanograms (ng)/milliliter (mL)
Coronary Artery Disease
Primary: Kaplan-Meier Estimate of 1-Year Target Lesion Failure (TLF) — 5.7 Percentage of events — p=<0.0001
Breast Cancer · Invasive Breast Carcinoma
Primary: Intervention Feasibility — 1; 3; 8; 6 Participants
Diabetes Mellitus · Diabetes Mellitus, Type 1 · Diabetes Mellitus, Type 2
Primary: Accuracy of CGM System Through 90 Days Post-Insertion (MARD for Paired CGM and Reference Glucose Measurements) — 9.6 percent
Covid19 · Severe Acute Respiratory Syndrome · SARS-CoV-2 Infection
Primary: Number of at Least Possibly Related Grade 3 Adverse Events (AE) and Serious Adverse Events (SAE) — 0; 1; 0; 0 adverse events
Diabetes Mellitus, Type 2
Primary: Incidence Rate of Expanded Major Adverse Cardiovascular Event (MACE) Composite Outcome - OT Analysis — 36.1; 35.9 Events per 1000 person-years
Acute Sore Throat
Primary: Reduction in Pain — 6.4; 6.2; 2.6; 6.0 score on a scale
Atrial Fibrillation
Primary: Safety Event Free Rate — 373 Participants