Phase 4 N=61 Preoperative Pain Control in Gastric Bypass Surgery Patients
Post-operative Pain
Primary: Post-operative Pain Medication Requirements — 13.76; 17.32; 40.89; 46.63 MME — p=0.10
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=20 CNS Study of Patients Switching From Tacrolimus to Envarsus
Renal Transplant Patients
Primary: Change in Quality of Life — 2.7; 1.35; 0.2 score on a scale
Phase 4 N=25 Comparison of Insulin Degludec With Insulin Glargine U100 for Adults With Type 1 Diabetes Crossing Multiple Time Zones.
Diabetes Mellitus, Type 1
Primary: Continuous Glucose Monitoring - Time in Range (70-140 mg/dl) — 36.3; 45.6; 37.2; 43.9 percentage of Time in Range 70-140mg/dL — p=<0.05
Phase 4 N=85 Advancing Personalized Antidepressant Treatment Using PET/MRI
Depression
Primary: Change From Baseline in Hamilton Depression Rating Scale at 8 Weeks — 11.81; 9.41 score on a scale
Phase 4 N=220 Losartan Effects on Emphysema Progression
Emphysema
Primary: Change in Mean pct950 — 1.35; 0.66 percentage of voxels — p=0.133
Phase 4 N=141 DPE Technique in Labor Epidural for Morbidly Obese Women
Morbid Obesity · Labor Pain
Primary: Number of Participants Who Required Asymmetric Block, Top-up Interventions, Catheter Adjustments, Replacement of Epidural Catheter, or Failure of Block Requiring…
Phase 4 N=68 Onabotulinumtoxin Type A Reconstitution With Preserved Versus Preservative-free Saline in Chronic Migraine.
Chronic Migraine, Headache
Primary: Verbal Pain Scale — 5.3; 3.3 score on a scale
Phase 4 N=198 A Comparison of NSAIDs for Acute, Non-radicular Low Back Pain.
Back Pain Without Radiation · Low Back Pain
Primary: Change From Baseline to Day 5 in Functional Impairment — 11.9; 9.4; 10.9 score on a scale
Phase 4 N=22 Pramlintide (Symlin) for the Treatment of Hypoglycemia Following Gastric Bypass Surgery
Hypoglycemia · Evidence of Previous Gastric Surgery
Primary: Plasma Glucose Levels in Response to Mixed Meal Testing - Area Under the Curve for Plasma Glucose — 2828; 2893 mg*min/dL — p=0.90
Phase 4 N=50 Study of Brentuximab Vedotin in Participants With Relapsed or Refractory Systemic Anaplastic Large Cell Lymphoma
Lymphoma
Primary: Objective Response Rate (ORR) — 64 percentage of participants
Phase 4 N=50 Evaluation of Calcineurin-inhibitor Reduction With Conversion at 2 Months to Everolimus/Reduced Tacrolimus in Renal Transplant Recipients Following Campath® Induction
Renal Transplant
Primary: Renal Function — 65.70 mL/min/1.73 m2
Phase 4 N=44 Post-cesarean Analgesia With Epidural Morphine Following Epidural 2-chloroprocaine
Physiological Effect of Drugs · Morphine · Analgesics
Primary: Total Amount of Opioid Used — 15; 0 milligrams
Phase 4 N=1,370 Rectal Indomethacin to Prevent Post ESWL-pancreatitis
Pancreatitis
Primary: the Incidence of Post-ESWL Pancreatitis — 60; 84 Participants
Phase 4 N=619 Optimizing Outcomes of Treatment-Resistant Depression in Older Adults
Treatment Resistant Depression · Major Depressive Disorder · Treatment-Refractory Depression
Primary: Psychological Well-Being — 34.7; 35.0; 34.8; 33.1 t-score — p=0.010
Phase 4 N=60 Pharmacokinetics of Preoperative Vancomycin
Surgical Site Infection · Vancomycin
Primary: Pharmacokinetics Analysis: V˅c — 2.56; 1.14 L