Phase 2 N=32 The Use of Heliox in Obstructive Sleep Apnea Syndrome
Obstructive Sleep Apnea Syndrome
Primary: Apnea Hypopnea Index — 42.71; 40.95 Apneas or hypopneas per hour sleep
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=40 2 Regimens of Lactulose for Colonoscopy Preparation in Adults
Colonoscopy Preparation
Primary: Efficacy of Lactulose as a Preparation for Colonoscopy. — 8.2; 7.2; 7.5; 8.4 units on a scale
Phase 2 N=136 A Study to Define the ECG Effects of Tizanidine Compared to Placebo and the Positive Control, Moxifloxacin, in Healthy Men and Women Using a Blinded ECG Evaluator: A Thorough ECG Trial
Spasticity
Primary: The Primary Endpoint Will be the Baseline-adjusted, Placebo-corrected Effect on QTc (ΔΔQTc) on Day 14. — -4.3; -0.5; -3.7; -2.0 milliseconds (msec)
Phase 2 N=300 Safety and Immunogenicity of a Single Dose of Intranasal Seasonal Trivalent Live-Attenuated Influenza Vaccine
Influenza
Primary: Number of Participants With Serious Adverse Events (SAEs), All-cause Hospitalizations, and Protocol-defined Wheezing Illness (PDWI) Episodes — 6; 0; 13; 16 participants
Phase 2 N=32 Exercise Intolerance in Renal Failure
Kidney Failure, Chronic
Primary: Change in Resting Muscle Sympathetic Nerve Activity (MSNA) — -7.5; 3.2 bursts/minute
Phase 2 N=100 How Pregnant Women and Their Babies Metabolize Ondansetron Compared to a Group of Non-pregnant Women
Postoperative Nausea
Primary: Volume of Distribution Estimated Pharmacokinetic Parameter — 27.9; NA Liters — p=<0.05
Phase 2 N=5 Ledipasvir/Sofosbuvir Fixed-Dose Combination in Adults With Nosocomial Genotype 1 HCV Infection
Hepatitis C
Primary: Percentage of Participants With Sustained Virologic Response (SVR) at 12 Weeks After Discontinuation of Therapy (SVR12) — 100.0 percentage of participants
Phase 2 N=142 Capecitabine vs. S-1 in Unresectable or Recurrent Breast Cancer
Breast Neoplasms
Primary: Progression Free Survival — 1.2; 1.3 years
Phase 2 N=173 Safety and Efficacy of Merlin (Ethanol and Glycolic Acid Mixture) for the Treatment of Cold Sores
Recurrent Herpes Labialis
Primary: Clinician Assessed Duration of Complete Healing of the Herpetic Episode — 129.6; 154.6 hours
Phase 2 N=61 Efficacy of Sofosbuvir With Ribavirin Administered Pre-Transplant in Preventing Hepatitis C Virus (HCV) Recurrence Post-Transplant
Hepatitis C · Hepatocellular Carcinoma
Primary: Percentage of Participants With Posttransplant Virologic Response (pTVR) at Posttransplant Week 12 — 75.0; 69.8 percentage of participants
Phase 2 N=30 Reclaim Deep Brain Stimulation Clinical Study for Treatment-Resistant Depression
Depression
Primary: Responders — 3; 2 participants — p==0.53
Phase 2 N=30 Influence of Hyaluronic Acid on Bacillus Calmette-Guérin Local Side Effects
Poisoning by BCG Vaccine
Primary: Visual Analogue Scale for Pain — 4.5; 4.9; 5.8; 4.2 units on a scale
Phase 2 N=12 Cangrelor Prasugrel Transition Study
Coronary Artery Disease
Primary: Extent of Preservation of Inhibitory Effect After Transition From Cangrelor to Prasugrel Compared With Effect Observed With Prasugrel Alone (Reference Timepoint) — 1.0…
Phase 2 N=15 FOLFOXIRI Plus Panitumumab Patients With Metastatic KRAS Wild-Type Colorectal Cancer With Liver Metastases Only
Colorectal Cancer
Primary: Overall Response Rate (ORR) — 75 percentage of evaluable participants
Phase 2 N=30 The Percutaneous Stem Cell Injection Delivery Effects on Neomyogenesis Pilot Study (The POSEIDON-Pilot Study)
Stem Cell Transplantation
Primary: Incidence of TE-SAE Define as Composite of Death, Non-fatal MI, Stroke, Hospitalization for Worsening Heart Failure, Cardiac Perforation, Pericardial Tamponade…