N/A N=59 Benefit of Lumbar Bracing for Chronic Low Back Pain Due to Degenerative Disc Disease
Degenerative Disc Disease · Lumbar Spondylosis · Low Back Pain
Primary: Pain Diary — 6.71; 5 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=100 Evaluation of the Benefits for Overall Health Following Cochlear Implant Treatment in the Elderly Population
Hearing Loss
Primary: Change in Health Related Quality of Life Following Cochlear Implant Treatment — 0.14; 0.22; 0.08 units on a scale
Phase 1 N=99 A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of KRP-A218 in Healthy Subjects
Healthy
Primary: Part A: Number of Participants With Adverse Events — 4; 3; 4; 3 participants
Phase 3 N=20 Evaluating the Efficacy of Dextromethorphan/Quinidine in Treating Irritability in Huntington's Disease
Huntington Disease · Irritability
Primary: Irritability as Assessed by The Irritability Scale. — 27.5 score on a scale
N/A N=494 Examining Validity and Reliability of the Shared Decision Making Process Survey in Adults With Depression
Depression
Primary: Shared Decision Making Process Score — 2.35; 2.51 score on a scale — p=0.092
N/A N=37 Amyloidopathy, Cholinopathy, Dopamine Responsiveness and Freezing of Gait in PD
Parkinson's Disease
Primary: L-DOPA Insensitivity — 5 Participants — p=0.00468
Phase 2 N=20 SGLT2 Inhibition in Older Obese Adults With Pre-diabetes
Aging
Primary: AGE-RAGE Measurement in Plasma — -172; -86 pg/mL
N/A N=18 Noise Reduction Preferences in Teenagers and Pre-teens
Hearing Loss
Primary: Subjective Rating of Listening Effort Questionnaire — 44.73; 44.5; 41.53; 35.86 units on a scale — p=0.007
Phase 2 N=52 Contralaterally Controlled Functional Electrical Stimulation Plus Video Games for Hand Therapy After Stroke
Upper Extremity Hemiplegia · Stroke
Primary: Box and Block Test Score — 10.6; 11.0; 11.2; 12.4 blocks
Phase 1 N=36 Effect of Stimulant Drugs on Social Perception
Healthy · MDMA ('Ecstasy')
Primary: Responses to Affective Touch — -1.24; 0.12; 0.19; 0.25 units on a scale
N/A N=301 Dose the Saline Reduce the Mucus Production When Water Exchange Colonoscopy is Used?
Colon Mucous · Colonoscopy
Primary: Left Colon Mucus Score — 0.2; 1.4; 0.5; 0.7 score on a scale
Phase 3 N=24 Safety and Efficacy of Intravenous OAV101 (AVXS-101) in Pediatric Patients With Spinal Muscular Atrophy (SMA)
Spinal Muscular Atrophy
Primary: Number of Participants With Treatment Emergent Adverse Events (AEs) and Serious Adverse Events (SAEs) by Weight Bracket — 7; 8; 9; 24 Participants
Phase 2 N=200 Trial on the Safety and Efficacy of MLS-101 in Patients With Uncontrolled Hypertension
Hypertension, Renal
Primary: Change From Baseline in Office-measured Systolic Blood Pressure (SBP) at Study Week 8 Compared to Placebo — -4.10; -11.3; -11.07; -5.63 mmHg
Phase 4 N=308 Efficacy, Safety, and Tolerability Study of Apremilast to Treat Early Oligoarticular Psoriatic Arthritis.
Arthritis, Psoriatic
Primary: Percentage of Participants Who Achieved a Clinical State of Minimal Disease Activity (MDA-Joints) Response at Week 16 — 16.0; 33.9 percentage of participants — p=0.0008
N/A N=401 Online Trial Examining Validity of the Shared Decision Making Process Survey With Video Vignettes
Colorectal Cancer · High Cholesterol
Primary: Shared Decision Making Process Score — 2.62; 1.82; 2.55; 2.06 score on a scale — p=0.21