6,678 trials
Gaucher Disease
Primary: Change From Baseline in Lumbar Spine Bone Mineral Density (BMD) Z-Score up to End of Study (EOS) (Week 103) — 0.17 Z-score
Obesity · Insulin Resistance · Gonadal Dysfunction
Primary: Insulin Sensitivity — 8.559; 3.425; 3.756; 2.985 x10-4/min-1/mIU/mL
Coronary Artery Disease · Diabetes Mellitus
Primary: Platelet Reactivity Measured by Vasodilator Stimulated Phosphoprotein (VASP) Platelet Reactivity Index (PRI %) — 25; 32; 31; 38 PRI% — p=0.105
Tennis Elbow · Epicondylitis, Lateral Humeral
Primary: Treatment Success - Event Rates in Each Group — 15; 24; 59; 48 percentage of participants
Breast Reconstruction · Anesthesia · Transverse Abdominis Plane Block
Primary: Amount of Supplemental Postoperative Narcotic Analgesia in Oral Morphine Equivalents (OME) — 19.8; 23.6; 20.7; 25.2 mg morphine equivalents
Appendicitis
Primary: Pediatric Quality of Life Inventory (PedsQL) Generic Core Scale - Parent — 91.3; 90.2 score on a scale
Type 1 Diabetes
Primary: Insulin Sensitivity by Hyperinsulinemic Euglycemic Clamp — 3.27; 3.46 mg/kg/min
Endoscopy · Insufflation
Primary: Change in Abdominal Distension — 0.9; 0.5; 1.1; 0.9 cm
End Stage Renal Disease
Primary: Time for Complete Infusion of 4.5 mL Triferic AVNU Pre-Dialyzer — 1.7 hours
Degenerative Disc Disease · Trauma (Including Fractures) · Spondylolisthesis
Primary: Radiological Assessment : Fusion Status — 20 participants
Coronary Artery Bypass Graft and/or Aortic Valve Replacement Surgery
Primary: Time to Extubation — 126.0; 219.0 minutes
Psoriasis
Primary: Percentage of Participants Who Achieved a ≥ 4-point Reduction From Baseline in Dermatology Life Quality Index (DLQI) at Week 16 — 41.3; 73.3 percentage of participants…
Hyperphosphatemia
Primary: Phosphorus Levels — 5.3; 5.6; 5.4; 6 mg/dL
Gout · Chronic Kidney Diseases
Primary: Percentage of Participants Experiencing ≥ 1 Gout Flare During Phase 3 — 135; 165 Participants — p=<0.001
Opioid Dependence
Primary: # of Participants Retained on Any Form of Community Buprenorphine (Not Randomzied tx) at Week 8 — 18; 9 Participants