65,437 trials
Sensitivity
Primary: Sensory Function — 46.7; 46.4; 46.1; 45.9 Degrees celsius — p=0.592
Human Immunodeficiency Virus
Primary: Proportion of Time on Medication Among Pregnant Women — 0.67; 0.66 proportion of days with medicaiton
HIV Infections · Kidney Diseases
Primary: Mean Glomerular Filtration Rate by Iohexol Clearance at Week 52 — 37.0; 40.1 mL/min/1.73 m²
Generalized Myasthenia Gravis
Primary: Percentage of Participants With Treatment-emergent Adverse Events (TEAEs) — 76.0; 78.6 percentage of participants
Human Immunodeficiency Virus · Obstructive Sleep Apnea
Primary: Reaction Time Measured Using the Psychomotor Vigilance Task — 346; 353; 348 ms
Hearing Loss · Ear Diseases · Hearing Disorders
Primary: Change in Consonant Nucleus-Consonant (CNC) Word Recognition Test (Implanted Ear Only) — 2.13; 61.14 percentage of recognized words
Musculoskeletal Pain
Primary: Percentage of Subjects With 30% or Greater Change in Pain Rating on the Visual Analog Scale (VAS) — 81.4 percentage of subjects
Wilson Disease
Primary: Maximum Observed Plasma Concentration (Cmax) Of Celecoxib With And Without The Coadministration Of ALXN1840 — 637.1; 567.4 ng/mL
Palliative Care
Primary: Change in Preparedness for Caregiving Scale Score — 0.3; 0.0 score on a scale
Cancer
Primary: Overall Response Rate (ORR) in the Anaplastic Thyroid Cancer (ATC) Cohort — 56; 56; 53; 53 Percentage of Participants
Cataract · Aphakia
Primary: Percentage of First Implanted Eyes Achieving Best-Corrected Distance Visual Acuity (BCDVA) of 0.3 Logarithm Minimum Angle of Resolution (logMAR) or Better at 1 Year…
Cigarette Smoking Behavior
Primary: Intention to Quit Smoking — 4.814; 4.844 Score on a scale
Type 1 Diabetes Mellitus
Primary: Low Blood Glucose Index (LBGI) — 1.4; 1.9 index score
Influenza A H3N2
Primary: Number of PCR-confirmed Influenza Infections — 17; 3 Participants
Healthy Participants
Primary: Area Under the Plasma Concentration-Time Profile From Time 0 Extrapolated to Infinite Time (AUCinf) for Ritlecitinib — 361.1; 370.1; 385.1 nanograms*hours/milliliter…