Phase 2 N=100 Brief Intervention in At-Risk First-time Mothers
Substance Use
Primary: Alcohol Use — 1.37; 0.92 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=140 Young Parents Program, Project Connect
Adolescents · 18 and Under When Child Was Born for Mothers · 25 and Under When Child Was Born for Fathers
Primary: Rapid Repeat Pregnancy — 8; 16 Participants — p=.037
N/A N=302 Communication and Coping for Mothers of Adolescents With Type 1 Diabetes
Type 1 Diabetes Mellitus
Primary: Glycemic Control (A1C) — 8.4; 8.5 Percentage of glycated hemoglobin
N/A N=164 Tools For Teen Moms: Reducing Infant Obesity Risk
Adolescent Mothers · Infant Obesity
Primary: Change in Infant Growth — -0.46; -0.44; -0.33; -0.46 Weight for age Z-score
Phase 4 N=96 Postpartum Etonogestrel Implant for Adolescents
Adolescence · Contraception · Postpartum
Primary: Continuation at 1 Year — 21; 30 participants
N/A N=37 Reducing Adolescent Pregnancy in the Emergency Department
Contraception · Adolescent Behavior · Emergency Department
Primary: Adolescent Feasibility of Intervention — 4.5; 4.7 score on a scale
N/A N=48 Improving Future Thinking Among Mothers to Reduce Harsh Parenting and Improve Child Outcomes
Behavioral Health
Primary: Change in Monetary Choice Questionnaire — -3.86; -4.13; -4.33 score on a scale — p=.191
N/A N=135 Reducing Adolescent Pregnancy
Pregnancy in Adolescence · Counseling · Contraception Behavior
Primary: Intention to Initiate Contraception — 59 Participants
N/A N=146 Reducing Teen Pregnancy in the Emergency Department
Reproductive Behavior · Sexual Behavior · Adolescent Behavior
Primary: Potential Efficacy: Effective Contraception Initiation Rates [Time Frame: Enrollment, 12 Weeks Post-enrollment (2 Weeks Post Close of Intervention)] — 14; 14 Participants
Phase 3 N=81 Immediate Versus Delayed Insertion of Implanon in Postpartum Adolescents
Contraceptive Usage
Primary: Number of Participants With Contraceptive Implant Continuation at Six Months Postpartum — 15; 7 Participants
N/A N=240 An Intervention to Reduce Risk Factors for Adolescent Pregnancy
Behavioral Changes
Primary: Sexual/Reproductive Health Behaviors — 24; 17 Participants
N/A N=102 Optimizing Pregnancy and Treatment Interventions for Moms 2.0
Pregnancy, High Risk · Opioid-Related Disorders · Pregnancy Related
Primary: Opioid Use Disorder (OUD) and Other Substance Use Disorder (SUD) Treatment Linkage/Retention — -1.5; -8.8 Percentage of days
N/A N=15 (YMP) Young Moms Program
Chronic Toxic Stress · Developmental/ Behavioral Regression in Young Children
Primary: Protective Factors Survey Score — 104.7; 98 score on a scale
Phase 2 N=107 Interactive Motivational Media for Perinatal Drug Abuse - 3
Substance-Related Disorders
Primary: Number of Participants With Drug Use at 3 Months — 49; 48 participants
N/A N=574 Healthy Mothers-Healthy Children Nutrition
Overweight and Obesity · Adiposity · Nutrient; Excess
Primary: Change in Mother's Height From Baseline (Time 1) to Time 2 — -0.00977; 0.000505 Centimeters
N/A N=630 Maternal Adversity, Vulnerability and Neurodevelopment
Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse) · Infant Development · Infant Behavior
Primary: Child's Cognitive Development Measured Using the Bayley Scales of Infant Development II. — 524; 508; 458; 422 Participants
Phase 3 N=302 The MOM Program: 5 Year Follow-up Study of a Home Visiting Program at The Children's Hospital of Philadelphia
Child Development
Primary: Wechsler Preschool and Primary Scale of Intelligence, Third Edition (WPPSI-III) — 86.5; 87.4 Scores on a scale — p=0.59
N/A N=426 A Randomized Controlled Trial to Improve Mother-Infant Synchrony Among Women With Childhood Adversity
Parent-Child Relations · Maternal Behavior · Infant Behavior
Primary: Mother-Infant Synchrony, Gaze and Affect — 113.89; 106.72; 28.2; 16.1 seconds of synchrony
N/A N=344 New Haven MOMS Partnership
Depression · Stress
Primary: Total Outpatient Mental Health or Substance Abuse Visits — 1.03; 1.21 visits — p=0.172
N/A N=42 Helping Moms to be Healthy After Baby
Weight Loss · Diet Modification · Obesity
Primary: Feasibility of Recruitment — 22; 19 participants
N/A N=252 Collaborative Perinatal Mental Health and Parenting Support in Primary Care
Parenting · Mother-child Relations
Primary: Change in Parent Sensitivity in Teaching — 36.73; 35.32 score on a scale — p=.026
N/A N=200 Intervention to Improve Developmental and Health Outcomes for Female Adolescents
Independent Child Migration
Primary: Intention to Migrate — 1.72; 1.15; 1.42; 1.28 Score on a scale — p=0.05
N/A N=99 SmokefreeMOM: Reaching Pregnant Smokers With Health Information Via Text Messaging
Pregnancy · Smoking Cessation
Primary: Smoking Abstinence — 4; 8 participants
N/A N=119 Improving Reproductive Health for Women in Opioid Medication-Assisted Treatment (OMAT)
Contraception
Primary: Family Planning Visit and Long-acting Reversible Contraception Use at Three and Six Month Follow-up by Condition. — 2; 7; 2; 7 Participants
N/A N=24 Parent-Adolescent Training on Neurofeedback and Synchrony
Testing Protocol With Healthy Individuals for Feasibility
Primary: Neurofeedback Rating Scale — 5.7 units on a scale
N/A N=74 Prenatal Breast Pump Education of Mothers and Their Support Person
Preterm Birth · Breast Feeding
Primary: Onset of Lactogenesis Stage II Through Volume Attainment — 84.8; 81 hours — p=0.985
N/A N=212 A Risky Sex Prevention Intervention for Middle School Age Minority Girls
HIV · Risky Sex Prevention
Primary: Adolescent Sexual Activity Index — 1.39; 1.45; 2.12; 1.90 score on a scale — p=0.62
N/A N=122 Adolescents With Substance Use Disorders Transitioníng From Residential Treatment to the Community
Substance Use · Adolescent Behavior
Primary: Change in Proportion of Days Used Outside of Controlled Environment — .27; .35; .35; .32 proportion of days used — p=.12
N/A N=3 Mindful Moms in Recovery
Opioid-use Disorder
Primary: Number of Participants Who Self-reported Retention in Medication Treatment for Opioid Use Disorder — 2 participants who reported 'yes' to MOUD
N/A N=20,670 Association Between Mother and Child Weight Gain: Statistical Methods With Validation
Obesity, Childhood
Primary: Obesity of the Child (in the Mother-child Pair) During the First 5 Years of the Child's Life — 1845 Participants