Clinical Trial Search

Primary: Control Status of Patients With Rhinosinusitis — 19.5; 36.8; 43.7 percentage of participants

Primary: Change in Rhinosinusitis Disability Index (RSDI) Score — -8.000; -14.82 units on a scale — p=0.505

Primary: Change in Nasal Polyp Score — .9; .3 score on a scale

Primary: Change in Sino-Nasal Outcome Test Scores (SNOT-22) — 23.18; 17.7 score on a scale

Primary: Change in Sino-nasal Outcome Test-22 Score Between Baseline and 6 Weeks, Then 6 Weeks to 12 Weeks. — 59.3; 52.9; 45.4; 51.8 units on a scale

Primary: Quality of Life (QoL) Outcomes Between Adenoidectomy + Maxillary Sinus Irrigation With or Without the Use of Balloon Dilation or Maxillary Sinus Ostia. — 2.48; 2.5…

Primary: Change From Baseline (CFBL) in the 7-day Average Composite Score of 3 Cardinal Symptoms (3CS) in Participants Without Nasal Polyps. — -2.13; -2.06 score on a scale

Primary: Sinonasal Outcome Test (SNOT 20) — 50.33; 53.14; 37 Score out of total 100

Primary: Total Subjective Symptoms Visual Analog Scores (VAS) — 20.4; 20.7; 9.7; 8.9 score on a scale

Primary: Number of Patients Recommended for Sinus Surgery After 3 Weeks of Antibiotic Therapy — 7; 8; 0; 6 Participants

Primary: Subjects Who Developed Antibiotic Resistance Organisms — 0; 0; 1; 0 Participants

Primary: Change in Lund-Kennedy Endoscopic Scores — -8.0; -1.5; -6.9 score on a scale

Primary: Number of Participants in Compliance With Medical Recommendations — 20; 10 participants

Primary: Nasal Obstruction/Congestion Score — 2.36; 2.35; 1.56; 1.79 units on a scale — p=0.0074

Primary: Sino-nasal Outcome Test (SNOT-22) Over Time — 43.8; 42.9; 39.7; 38.5 score on a scale — p=0.819

Primary: Comparison of Change in Chronic Sinusitis Survey (CSS) Score at 24 Weeks Compared to Baseline — 41.9; 27.0 Scores on a scale

Primary: Change From Baseline (CFBL) in the 7-day Average Composite Score of 3 Cardinal Symptoms (3CS) in Participants Without Nasal Polyps — -2.73; -1.61 Change from Baseline in…

Primary: Change From Baseline in Symptoms as Measured by a Composite Score for Each Symptom of Nasal Congestion, Facial Pain or Pressure Sensation, and Nasal Discharge (Anterior…

Primary: Change of Inflammation of the Nasal Mucosa and Paranasal Sinus — 0; -0.8 score on a scale

Primary: Mean Reduction in SNOT-20 Scores — 1.8; 5.5 units on a scale — p=0.23

Primary: Pain Severity — 12.4; 8.5 units on a scale

Primary: Product-related Unexpected Serious Adverse Events — 0; 0; 0 Participants

Primary: Objective (a) the Effect on Polypoid Mucosal Thickening in the Anterior Ethmoid and Maxillary Sinuses as Measured on Sinus CT Scan. — -8.9; 4.2 % Change

Primary: Change From Baseline to Week 16 in Sino-Nasal Outcome Test (SNOT) 22 Total Score — -18.1; -18.3 score on a scale — p=0.9499

Primary: Change From Baseline in Total Nasal Polyp Score at Week 52 — -2.458; -0.380 Score — p=<.0001

Primary: Change of Inflammation of the Nasal Mucosa and Paranasal Sinus — -2; -0.8 units on a scale

Primary: Randomized Cohort: Difference in Patency Grade of FSO — 1.6; 1.5 score on a scale

Primary: Sinus Symptom Improvement — -1.59; -1.60; 0.88; 0.88 units on a scale — p=<0.001

Primary: Ratio to Baseline in Peripheral Blood Eosinophil Counts After 6 Months of Treatment — 0.06 ratio to baseline — p=< 0.001

Primary: Nasal Obstruction/Congestion Score — 3.62; 3.30; 2.31; 2.62 units on a scale — p=0.1365