N/A N=439 Preventing Alcohol Exposed Pregnancy Among Urban Native Young Women: Mobile CHOICES
Alcohol Exposed Pregnancy
Primary: Alcohol Use — 86; 82; 131; 137 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=48 Adapting and Testing a Behavioural Intervention to Prevent FASD and Adverse Infant Outcomes
Maternal Behavior · Alcohol Drinking · Fetal Conditions
Primary: Number of Participants With Negative Urinalysis for Alcohol Metabolite (EtG) — 44 Participants
Phase 1 N=48 Computer-delivered Screening and Brief Intervention for Alcohol Use in Pregnancy
Alcohol Abuse
Primary: Alcohol Use — 18; 14 participants
N/A N=167 The Trajectory of Fetal Alcohol Spectrum Disorders (FASD) Across the Life Span: Continuing Prevention and Longitudinal Epidemiology
Fetal Alcohol Spectrum Disorders
Primary: Change in the Alcohol Use Disorders Identification Test (AUDIT) Score Over Time — -5.8; -4.0 score on a scale
N/A N=185 Computerized Tool for Preventing Prenatal Drinking
Foetal Exposure During Pregnancy
Primary: Number of Participants Reporting Risky Alcohol Use — 99; 86; 60; 48 Participants
N/A N=60 Maternal Alcohol Reduction Intervention in South Africa [MaRISA]
Maternal; Alcohol Use, Affecting Fetus
Primary: Urine Ethylglucuronide (EtG) Testing — 0 Participants
Phase 2 N=60 Postnatal Choline Supplementation in Children With Prenatal Alcohol Exposure
Fetal Alcohol Spectrum Disorders · Fetal Alcohol Syndrome · Partial Fetal Alcohol Syndrome
Primary: Side Effects of Choline Bitartrate — 8; 10; 8; 9 participants
N/A N=134 Records for Alcohol Care Enhancement
Alcohol Use Disorder (AUD)
Primary: Percent of New Alcohol Use Disorder (AUD) Diagnosis Episodes That Meet Criteria for AUD Treatment Engagement Among Patients With a New AUD Diagnosis Who Are Empaneled to…
N/A N=132 Brief Intervention to Prevent Alcohol Socialization (BIPAS Alcohol)
Alcohol Drinking, Adolescent · Drinking Behavior · Drinking, Alcohol
Primary: Change in Mean Value of Parental Pro-sipping Beliefs Score — 0.13; 0.08 score on a scale
N/A N=60 Computer-delivered Screening & Brief Intervention for Marijuana Use in Pregnancy
Marijuana Use · Pregnancy
Primary: Number of Participants Abstinent From Marijuana for the 7 Days Prior to Delivery — 6; 7; 6; 3 Participants
N/A N=122 PrEP and Alcohol - Enhancing HIV Pre-Exposure Prophylaxis (PrEP)
Hazardous Alcohol Use
Primary: Intervention Feasibility: Intervention Uptake — 122 Participants
Phase 2 N=46 Choline Supplementation as a Neurodevelopmental Intervention in Fetal Alcohol Spectrum Disorders
Fetal Alcohol Spectrum Disorders
Primary: Elicited Imitation Memory Task - Short Delay Memory Measure: 6 Months — 0.252; 0.183 change in percentage correct
N/A N=20 Alcohol and Breast Cancer (ABC) Trial
ER+ Breast Cancer · Breast Cancer · Aromatase Inhibitors
Primary: Blood Levels of Total Estradiol Concentration — -0.50; -0.39 Log scale, pg/mL
N/A N=44 Cognitive Training and tDCS for Children With FASD
Fetal Alcohol Spectrum Disorders
Primary: BrainHQ Learning Rate — 867.6; 861.7 milliseconds
N/A N=37 Biobehavioral Pathways Underlying Alcohol Use and Health
Alcohol Use Disorder · Liver Diseases
Primary: Percentage of Screen Eligible Who Enroll — 28; 5 Participants
Phase 4 N=302 Alcohol Drinkers' Exposure to Preventive Therapy for TB (ADEPTT)
Tuberculosis · HIV/AIDS · Alcohol Abuse
Primary: Cumulative Incidence of Participants Experiencing a Grade 3/4 Hepatotoxicity — 8.3 percent
N/A N=12 The Effects of Alcohol Consumption on Central Adiposity
Alcohol Drinking · Weight Loss · Adiposity
Primary: Change in Central (Abdominal) Adiposity — -0.250; -0.071 kg — p=<0.231
N/A N=365 Protective Behavioral Strategies and Brief Alcohol Interventions
Alcohol Consumption
Primary: Drinks Per Week — 12.55; 9.57; 13.74 drinks per week
N/A N=66 BabySTEPs: Supportive Texts to Empower Parents
Alcohol Drinking
Primary: MRT Feasibility — 77.05 percentage of surveys completed
N/A N=1,053 Evaluations of Alcohol Warning Labels
Oral Cancer · Esophageal Cancer · Larynx Cancer
Primary: Dwell Time — 8.75; 8.47 seconds
Phase 2 N=32 Phase IIa Study of Fomepizole for Acetaldehyde Toxicity After Ethanol Exposure in Subjects With Altered Ethanol Metabolism
Aldehyde Dehydrogenase-2 (ALDH2) Deficiency
Primary: Number of Participants With Adverse Events (AEs), Serious AEs, and AEs Leading to Study Discontinuation — 13; 6; 8; 21 Participants
Phase 2 N=100 Brief Intervention in At-Risk First-time Mothers
Substance Use
Primary: Alcohol Use — 1.37; 0.92 units on a scale
N/A N=176 Technology-Based Intervention for Reducing Sexually Transmitted Infections and Substance Use During Pregnancy
Sexually Transmitted Infection · Alcohol Use Complicating the Puerperium · Alcohol Use Complicating Pregnancy, Unspecified Trimester
Primary: Unprotected Sexual Occasions (USOs) — 27.73; 41.50; 8.68; 14.70 USOs per participant — p=0.2964
N/A N=1,123 Impacts of Alcohol Warning Labels: An Online Experiment
Alcohol Drinking
Primary: Perceived Message Effectiveness — 2.66; 2.54; 2.52; 2.50 score on a scale — p=<0.001
Phase 3 N=100 Topiramate and Prolonged Exposure
PTSD and Alcohol Use Disorder
Primary: CAPS-5 Change — 36.720; 38.600; 21.006; 29.872 score on a scale
N/A N=202 Parental Research on Interventions for Social Media
Underage Drinking
Primary: Acceptability (Parent)- Program Usefulness — 42 Participants
Phase 2 N=119 Integrated Alcohol Disorder and PTSD Treatment
PTSD · Alcoholism
Primary: Clinician Administered PTSD Scale (CAPS) — 43.2; 42.1; 25.8; 32.9 score on a scale — p=.002
Phase 2 N=200 Oxytocin, Alcohol Craving, and Intimate Partner Aggression
Alcohol Use
Primary: Change in Alcohol Craving — 0.90; 1.21 score on a scale
Phase 2 N=51 Medication Development in Alcoholism: Apremilast Versus Placebo
Alcohol Use Disorder
Primary: Craving to Drink — 33.84; 28.31 score on a scale — p=0.36
N/A N=98 Clinical Follow-up and Outcomes of Pregnancies Exposed to Ella
Emergency Contraception
Primary: Number of Participants Who Experienced Assessed Pregnancy Outcomes — 1; 0; 1; 0 Participants