Phase 4 N=100 Single Shot Versus OnQ Pump in Extremity Fractures
Pain · Fracture
Primary: Change in Score on Visual Analog Scale (VAS) — 3.28; 1.47; 3.62; 3.91 score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=720 Comparing the Efficacy of Oral Opioids for Outpatient Acute Pain Management After ED Discharge Discharge
Analgesia After ED Discharge for Extremity Injuries
Primary: Difference in Pain Intensity Score Before and After Last Dose. — 7.6; 7.6; 7.9; 7.9 units on a scale
Phase 4 N=416 Comparative Efficacy of 4 Oral Analgesics
Pain
Primary: Between Group Difference in Change in Numerical Rating Scale (NRS) Pain Scores — 4.4; 3.5; 3.9; 4.3 units on a scale
Phase 3 N=78 4-drug Nerve Block Versus Plain Local Anesthetic for Knee and Hip Arthroplasty Analgesia in Veterans
Pain
Primary: Short-Form McGill Pain Questionnaire (Version 2) Total Score Difference From Baseline — -1.85; -0.05 score on a scale — p=0.003
Phase 4 N=90 Analgesia After Total Knee Arthroplasty: Peri-Articular Injection Versus Epidural + Femoral Nerve Blockade
Readiness to Discharge
Primary: The Primary Outcome is Time Until a Patient is "Ready for Discharge." — 3.2; 3.2 days
Phase 4 N=60 A Comparison of Proprietary Formulations of Oral Ketamine + Aspirin and Oral Ketamine Alone for Musculoskeletal Pain
Pain
Primary: Change in Pain Score at 60 Minutes — 2.18; 4.01 units on a scale
Phase 3 N=90 Pain Reduction With Intranasal Medications for Extremity Injuries
Pain · Traumatic Limb Injury
Primary: Difference From Baseline in Visual Analog Scale Pain Score — -30.6; -31.9 score on a scale
Phase 4 N=64 Ultrasound Guided Pain Control Versus Standard Treatment in Emergency Department HIP Fracture Patients
Hip Fracture
Primary: Pain Score at 30 Minutes — 1.94; 2.05; 5.13 units on a scale — p=<.0001
N/A N=90 Analgesia After Total Hip Arthroplasty: Peri-Articular Injection Versus Epidural Patient Controlled Analgesia (PCA)
Osteoarthritis
Primary: Time Until Patient is Ready for Discharge — 2.4; 2.3 days
N/A N=501 Oral Analgesic Utilization for CHildhood Musculoskeletal Injuries
Musculoskeletal Injury
Primary: Pain Intensity - Percentage of Children Who Achieved VAS < 30 mm — 33.0; 29.3; 29.9 Percentage of participants — p=0.81
N/A N=711 Efficiency And Quality In Post-Surgical Pain Therapy After Discharge
Opioid Use · Opioid Dependence · Opioid Misuse
Primary: Cumulative Weekly Opioid Intake After Discharge — 30; 30; 20; 10 Morphine milligram equivalents
Phase 4 N=102 Efficacy of Peri-Incisional Multimodal Drug Injection Following Operative Management of Femur Fractures
Pain, Postoperative · Femur Fracture
Primary: Visual Analog Scale Pain Assessment — 5.0; 5.0; 1.6; 3.2 units on a scale
Phase 4 N=100 Efficacy of Multimodal Periarticular Injections in Operatively Treated Ankle Fractures
Pain, Postoperative · Ankle Fractures
Primary: Change in Post-operative Visual Analog Pain Scores (VAS) — 42; 52; 41; 50 0 to 100 score on a scale
Phase 4 N=100 A Multimodal Analgesia Protocol Adapted for Ambulatory Surgery
Opioid Use
Primary: Amount of Pain Experienced — 28; 35 Score on a scale
Phase 4 N=180 Minimal Opioid Use After Total Hip Replacement (THR)
Osteoarthritis, Hip
Primary: Opioid Use — 30; 22.5; 15 Oral Morphine Equivalent (mg)
N/A N=108 Duration of Analgesia After Popliteal Fossa Nerve Blockade: Effects of Dexamethasone and Buprenorphine
Patients Undergoing Ankle Surgery
Primary: Time it Takes for Nerve Block to Wear Off — 30.4; 45.1; 32.2; 45.6 hours
N/A N=636 Effectiveness and Feasibility of Patient Controlled Analgesia in the ED
Pain
Primary: Rate of Change in Pain Intensity Per Hour — 1.3; 0.3 Score on a scale per hour — p=<0.001
Phase 2 N=600 Comparing Five Oral Analgesics for Treatment of Acute Pain in the Emergency Department (ED)
Musculoskeletal Pain
Primary: Change in Pain From Before Medication Administered (Baseline) to One-hour Post-baseline — 3.0; 3.0; 3.4; 3.1 Units on a scale — p=0.69
Phase 4 N=323 A Randomized Study of Three Medication Regimens for Acute Low Back Pain
Acute Low Back Pain
Primary: Change in Functional Disability as Measured by the Roland Morris Disability Questionnaire — 5; 4; 7 units on a scale
Phase 4 N=190 Effects of a Surgical Site Injection on Pain Scores and Narcotic Use After Orthopaedic Trauma Surgery
Pertrochanteric Fracture
Primary: Amount (mg) of Narcotics (Oral Morphine mg Equivalents) Used — 16; 10 morphine milligram equivalents (MME)
N/A N=211 Safety and Efficacy of Patient Controlled Analgesia in the Emergency Department
Pain
Primary: Short Term Efficacy: Change in Pain Intensity as Assessed by Patient Self Report on Numerical Rating Scale — 3.8; 4.0; 3.6 Units on a scale — p=0.82
Phase 4 N=99 Assessing the Efficacy of IV Ibuprofen for Treatment of Pain in Orthopedic Trauma Patients
Pain
Primary: Efficacy of IV Ibuprofen in Orthropedic Trauma Patients — 74.9; 97.8 morphine equivalent dosage, mg
Phase 4 N=225 Adult Oral Ibuprofen Study for ED Pain Patients
Pain, Acute
Primary: Pain Reduction at 60 Minutes From Baseline of the 3 Oral Ibuprofen Groups — -2.12; -1.85; -1.96 units on a scale
Phase 4 N=14 Anesthesia for Pain After Ankle Fracture Surgery
Chronic Pain · Ankle Fracture Surgery · Regional Anesthesia
Primary: Pain Score at 12 Months - Experimental Group vs. Control Group — 36.33; 44.00 units on a scale — p=0.1269
N/A N=54 Analgesic Efficacy After Umbilical Hernia Repair in Children
Umbilical Hernia
Primary: The Amount of Intravenous and Oral Opioids Used by Patients Who Receive a Rectus Sheath Nerve Block and Those Who Receive Local Infiltration of the Surgical Site for…
Phase 2 N=38 Ultrasound-guided Femoral Nerve Blocks in Elderly Patients With Hip Fractures
Femoral Neck Fractures · Hip Fractures
Primary: Number of Participants Reporting at Least One NRS Rating — 18; 18 Participants
N/A N=106 QL vs PENG for Analgesia After Hip Arthroplasty
Block · Hip Replacement · Postoperative Pain
Primary: Postoperative Cumulative Opioid Consumption — 12.7; 9.9; 29.4; 23.2 morphine milligram equivalents
Phase 4 N=167 Postoperative Pain Management in Patients Undergoing Intramedullary Nail Fixation After Tibia and Femoral Fractures
Femur Fracture · Tibial Fractures
Primary: 12hrs VAS Pain Scores — 7.6; 7.9; 7.3; 7.2 score on a scale — p=0.215
Phase 4 N=60 Ketamine For Acute Treatment of Pain in Emergency Department
Pain
Primary: Change From Baseline of Pain as Described by Numeric Rating Scale (NRS) [Minimum:0, Maximum 10] at 15 Minutes — 3.5; 6.0 units on a scale
Phase 4 N=41 Dexmedotomidine for Acute Pain Control in Patients With Multiple Rib FracturesRandomized Controlled Trial
Rib Fractures · Pain, Acute
Primary: Evaluation of Pain — 4; 4 score on a scale