N/A N=60 Metatarsal Phalangeal Joint Deformity Progression - R01
Diabetes Mellitus (DM)
Primary: Change in Metatarsal Phalangeal Joint Angle (Degrees) in People With Diabetes From Baseline and at a 3-year Period — 0.8; -0.1 degrees
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=23 Weightbearing Assessment of Tarsal Instability
Adult-acquired Flatfoot Disorder (AAFD)
Primary: Change in Joint Motion Between Touch-down Bearing Navicular and Full-weight Bearing Navicular — 3.56; 4.36; -0.1666; -0.170 mm
N/A N=11 Do Rocker Bottom Shoes and Ankle-Foot Orthoses Reduce Pain and Improve Mobility for Ankle Osteoarthritis Patients
Ankle Osteoarthritis · Healthy Ankles
Primary: Daily Step Count (# Steps) — 3453; 2399; 3453; 2745 steps
N/A N=50 Agility LP Ankle Arthroplasty Outcomes
Rheumatoid Arthritis of Ankle · Osteoarthritis of Ankle · Traumatic Arthritis of Ankle
Primary: Assessment of Functional Outcomes Following Agility LP Ankle Replacement — 37.67; 37.07 Degrees
N/A N=273 Treatment Outcomes for Ankle Arthritis
Osteoarthritis
Primary: Musculoskeletal Functional Assessment (MFA) — -12.5; -15.0 units on a scale
N/A N=22 Iterative Design of Custom Dynamic Orthoses to Reduce Articular Contact Stress
Ankle Fractures · Post-traumatic Osteoarthritis · Osteoarthritis Ankle
Primary: Joint Contact Stress Time Exposure (Model Estimated) — 4.44; 3.97; 4.08; 4.25 MPa-s/gait cycle
N/A N=21 Cerebral Palsy: Ankle Foot Orthoses - Footwear Combinations
Cerebral Palsy (CP)
Primary: Change in Baseline Gait Profile Score (GPS) at 3 Months-individual Lower Extremity Joint Kinematics — 0.41; -0.48 units on a scale — p=0.36
N/A N=20 The Influence of Stability Boots on Gait Pattern in Healthy Adults
Rehabilitation After Ankle Injuries
Primary: ROM Ankle Joint — 31.4; 18.4; 21.2 degree
N/A N=107 Study of an Orthotic Designed to Equalize Leg Lengths for Patients With Injuries Managed in Walking Boots
Joint Pain · Trouble Balancing
Primary: Patient Reported Balance — 3.0; 2.1 units on a scale
Phase 3 N=30 Effects of CHONDRON (Autologous Chondrocytes) With Ankle Cartilage Defect
Articular Cartilage Defects of Ankle Joint
Primary: Average Change From Baseline in American Orthopedic Foot and Ankle Society(AOFAS) at 12 Months Post-surgery — 16.93 scores
N/A N=9 Computed Tomography for Evaluating Supination-external Rotation Type Ankle Fractures
Supination-external Rotation Ankle Fractures
Primary: Medial Clear Space Distance in the Ankle Joint — 1.41 mm
N/A N=9 Iterative Design of Custom Dynamic Orthoses
Adult ALL · Healthy
Primary: Joint Contact Stress-Time Exposure — 3.9; 3.5; 4.1; 2.7 MPa-s/gait cycle
N/A N=45 Ankle Robot to Reduce Foot Drop in Stroke
Stroke · Foot Drop
Primary: Gait Velocity During Self-selected Overground Walking — 0.48; 0.48; 0.54; 0.56 CM/SEC
N/A N=6 Gait in Children With Down Syndrome While Wearing Orthoses
Down Syndrome
Primary: Step Width — 10.4 cm
Phase 2 N=39 Bracing and Strengthening for Posterior Tibial Tendon Dysfunction
Posterior Tibial Tendon Dysfunction
Primary: Foot Function Index(FFI) — 16.0; 12.7; 8.1; 8.3 units on a scale
N/A N=50 Ankle Foot Orthosis Comparative Effect
Foot Injuries and Disorders
Primary: PROMIS Patient Reported Outcomes for Physical Function — 44.78; 45.02 score on a scale
Early Phase 1 N=11 Testing an Adjustable Ankle Orthosis During Walking in Cerebral Palsy
Cerebral Palsy
Primary: Change in Muscle Activity — -0.09 percent change based on mV/mV measures
N/A N=36 The Effect of Additional Neurodynamic Intervention in Patients With Chronic Ankle Instability
Ankle Sprains
Primary: Pressure Pain Threshold- Anterior Talofibular Ligament — 4.19; 3.98 kg/ cm²
N/A N=111 Brace Versus Casting in Pediatric Low Risk Ankle Fractures
Ankle Fracture
Primary: Functional Outcome as Measured by the Activities Scale for Kids at 4 Weeks From the Time of the Initial Injury — 85.3; 91.3 percentage of questions
N/A N=100 Associated Joint Pain With Controlled Ankle Movement (CAM) Walker Boot Wear
Pain · Ankle Injuries
Primary: The Presence and Severity of Secondary Site Pain — 31 Participants
N/A N=233 A Multicenter Randomized Trial Comparing Antiglide and Lateral Plate Fixation in Ankle Fractures
Ankle Injuries
Primary: Percentage of Nonpalpable Hardware — 71; 55; 64; 66 percentage of participants
N/A N=28 Ankle-foot Orthoses for Peripheral Artery Disease
Peripheral Artery Disease
Primary: Change in WIQ Distance Subscore — 22.7; -7.2 Scale units
N/A N=30 Shoe Lifts for Leg Length Inequality in Adults With Knee or Hip Symptoms
Leg Length Inequality · Osteoarthritis, Knee · Osteoarthritis, Hip
Primary: Change in Pain Intensity — -0.8; -2.9 units on a scale
N/A N=53 The Effect of Five-Toed Socks on Postural Control Among Active Individuals Who Have Chronic Ankle Instabilities
Ankle Sprain
Primary: The Primary Outcome Measurement for This Study Was to Determine Differences in Center of Pressure (COP) and Static Postural Control Patterns in Individuals With and…
Early Phase 1 N=9 Ankle Assistance and Resistance in Older Adults
Sarcopenia
Primary: Change in 6MWT — 48.3 m
N/A N=33 Improving Mobility in Peripheral Artery Disease Using an Ankle Foot Orthosis
Peripheral Artery Disease
Primary: Maximum Walking Time From the Gardner Graded Treadmill Protocol — 117.7; 197.5; 188; 339.9 Seconds
N/A N=56 AMPLEX Ankle Fusion and Hindfoot
Arthrodesis Surgery Involving the Hindfoot or Ankle
Primary: Proportion of Subjects Who Met All Five Criteria for Subject Performance Composite (SPC) Endpoint — 79.5; 35.3 percentage of subjects
N/A N=5 Assessing the DSR Ankle
Amputation · Limb Deficiencies
Primary: Minimum Foot Clearance — 4.07; 3.87 centimeters
N/A N=67 Outcomes of Compliance With Brace Wear in Clubfoot
Clubfoot
Primary: Wear Rate Percentage (Number of Hours Per Day Brace Was Worn Out of the Recommended 24 Hours) — 91.7; NA; NA; 86.8 percentage of time worn
N/A N=148 A Longitudinal Outcomes Study of the Subchondroplasty® Procedure in the Foot/Ankle
Insufficiency Fractures · Stress Fracture · Stress Fracture, Ankle, Foot and Toes
Primary: Foot Function Index-Revised (FFI-R) Short Form Score at 24 Months — 42.8; 43.0; 39.6 Percentage scale