30 closest matches · ranked by relevance
Relief of Joint Pain
Primary: Percentage Change in Average Joint Pain in Women With Aromatase Inhibitor-associated Musculoskeletal Symptoms (AIMSS) Compared to Baseline as Measured by the Brief Pain…
Aromatase Inhibitor Induced Musculoskeletal Syndrome (AIMSS) · Breast Cancer
Primary: Oxylipin Levels — 10.2; 12.1; 12.3 pg/mL — p=0.684
Arthralgia · Breast Cancer
Primary: Absolute Change in Brief Pain Inventory (BPI) Worst Pain From Baseline to Week 15 — -2.4 units on a scale
Ductal Carcinoma in Situ · Estrogen Receptor-positive Breast Cancer · Progesterone Receptor-positive Breast Cancer
Primary: Number of Participants With Aromatase Inhibitor Associated Musculoskeletal Symptoms (AIMSS) — 22 Participants — p=<0.001
Early Breast Cancer
Primary: Number of Participants With New Events of Arthralgia — 37 Participants
Breast Cancer · Arthralgia · Obesity
Primary: Effect of Change in Body Mass Index on Change in Grip Strength With Aromatase Inhibitor Therapy — -0.15; 2.44 kg/m^2 — p=0.03
Breast Cancer
Primary: Change in Percentage of Total Fatty Acids for Each Polyunsaturated Fatty Acid (PUFA) Group From Start of Omega-3 Fatty Acid (O3-FA) Supplementation to 3 Months of O3-FA…
Muscle Pain · Joint Pain
Primary: Change in Musculoskeletal Symptom Sub-scale on the Breast Cancer Prevention Trial Symptom Scale — -0.2; -0.5 units on a scale — p=0.38
Arthralgia
Primary: Knee Cartilage Volume — 2042; 1971 mm³
Breast Cancer
Primary: Number of Participants With Worsening of Musculoskeletal Symptoms (MS) — 23; 18; 24; 18 participants
Arthralgia · Breast Cancer · Hot Flashes
Primary: Change in Item #3 (Average) of the Brief Pain Inventory (BPI) Average Pain From Baseline to Month 3 — -1.9; -2.0 score on a scale — p=0.4952
Breast Cancer
Primary: Number of Participants Discontinuing Due to Grade 2 or Higher Arthralgia-myalgia. — 25 Participants
Breast Cancer · Low Bone Mineral Density · Osteopenia
Primary: Lumbar Spine Bone Mineral Density Percent Change From Baseline at Month 12 — 4.8; -.7 Percent Change from Baseline — p=<0.0001
Hypogonadism · Severe Obesity
Primary: Percent Change in Muscle Strength as Assessed by Knee Extension and Knee Flexion — 12.6; 8.9; 12.8; 3.7 Percent change in muscle strength
Breast Cancer · Joint Pain
Primary: Change in WOMAC Score — 24.9 Score on a scale — p=0.004
Breast Cancer · Other Disorders of Bone Density and Structure
Primary: Mean Percentage Change in Lumbar Spine Bone Mineral Density From Baseline (Before Chemotherapy Commencement) to Month 12 of AI Therapy — -0.72 percentage of change
Breast Cancer · Osteoporosis · Osteopenia
Primary: Change in Intestinal Calcium Absorption Related to Aromatase Inhibitor Therapy — 16 percent calcium absorption
Breast Cancer
Primary: Percentage of Patients Who Experience 30% Reduction in Average Pain Score From Baseline to 8 Weeks Due to Duloxetine Therapy. — 72.4 percentage of participants
Breast Cancer · Pain · Arthralgia
Primary: Mean Pain50 Assessed at Baseline, 3 Months and 6 Months — 4.3; 4.2; 4.2 kg/cm^2
Breast Neoplasms
Primary: Part A Correlation of Day 29 Estradiol With BMI — 0.06 correlation coefficient
Short Stature
Primary: Predicted Adult Height at Year 3 — 167.8; 169.4 cm
Osteoporosis · Breast Cancer
Primary: Mean Percent Change in Total Volumetric Bone Mineral Density (BMD) Measured by High Resolution Peripheral Quantitative Computer Tomography (HR-PQCT) From Baseline to 24…
Hypogonadism
Primary: Change in Lean Body Mass — -2000; -1500 grams
Breast Neoplasms
Primary: Number of Participants With Factors Considered to Affect the Safety and/or Efficacy of Exemestane — 126; 324; 372; 68 participants
Bone Loss · Osteoporosis · Breast Cancer
Primary: BMD of Spine by DXA — 2.269; -1.735 percentage change
Breast Cancer
Primary: Number of Women With Reduced Breast Parenchymal Enhancement — 7 Number of participants
Breast Neoplasms
Primary: Time-to-Event — NA months
Breast Neoplasms
Primary: Time to Progression (TTP) - Expert Evaluation Committee Assessment — 13.8; 11.1 months
Arthralgia · Musculoskeletal Complications · Pain
Primary: Number of Early Breast Cancer Patients Prescribed Adjuvant Letrozole That Are Vitamin D Deficient and Who Experience Myalgias, Arthralgias and/or Joint Stiffness — 12; 1…
Breast Cancer
Primary: Number of Participants With Local Recurrence in Breast — 6 Participants