Clinical Trial Search

Primary: Change From Baseline in the Pervasive Developmental Disorder-Behavioral Inventory (PDDBI) - Autism Composite Score — -4.5; -6.4 units on a scale — p=0.5

Primary: Pediatric Anxiety Rating Scale (Measures the Severity of Anxiety Symptoms) — 16.33; 17.62; 11.58; 16.05 units on a scale

Primary: Pediatric Anxiety Rating Scale. — 11.62; 14.04 units on a scale — p=.04

Primary: Clinical Global Impressions-Improvement — 1.8 units on a scale

Primary: Change in Score on Conners Adults Attention Deficit Hyperactivity Disorder (ADHD) Rating Scale — 68.6; 71.8; 53.4; 57 T-score

Primary: Change From Baseline in Anxiety Severity on the Pediatric Anxiety Rating Scale After 16 Weeks of Treatment. — 3.43; 3.47; 3.28; 2.13 units on a scale

Primary: Social Responsiveness Scale (SRS) — 16.5; 89.06; 14.5; 79.8 Points

Primary: Change in Ohio Autism Clinical Impressions Scale - Improvement (OACIS-I) Average Score From Baseline — 0.28; 0.28; 0.28; 0.33 score on a scale

Primary: Change From Baseline in Aberrant Behavior Checklist-Irritability at 12 Weeks — 7.6; -0.6 units on a scale

Primary: Total Brain Volume — 1634.1; 1409.8; 1236.7; 1401.9 cubic centimeters

Primary: Percent Change of ABC - Irritability Subscale Score — -44.5 percent change in scores

Primary: Change in ASD Symptoms Social Responsiveness Scale 2 (SRS-2) Scale. — -30.6 scores on a scale

Primary: A Number of Participants With Non-serious and Serious Adverse Events 24 Hrs Post-transfusion — 0; 0; 0; 0 participants

Primary: Change in Language (Total Standard Score, Range 40 - 160) — 79.62; 79.66; 80.45; 80.59 units on a scale

Primary: Change From Baseline in Parent Rated Social Responsiveness Scale (SRS) Scores During Treatment. — 9.73; 3.18 units on a scale — p=0.0275

Primary: Change From Screening/Baseline in Social Responsiveness Scale (SRS) at 4 Weeks, 10 Weeks, 18 Weeks and 22 Weeks — -7.79; -14.76; -1.38; -14.48 units on a scale

Primary: Mean Conners' Teacher ADHD Index T Score by Dose — 72.8; 63.1; 63.6; 61.5 Units on a scale (T-scores) — p==.001

Primary: Pediatric Anxiety Rating Scale — 7.79; 15.06 units on a scale

Primary: Autism Diagnostic Observation Schedule, 2nd Edition (ADOS2) — -1.6; -0.4 units on a scale — p=0.0028

Primary: Resting State Functional Connectivity (rsFC) Salience Network (Anterior Cingulate Cortex (ACC) and Insula Versus Visual Cortex) — 0.338; 0.400; 0.428; 0.522 z-scores…

Primary: Spatial Attention Baseline — 80.3; 43.0 Percent Correct

Primary: Baseline and Week 8scores on Children's Yale-Brown Obsessive Compulsive Scale - Pervasive Developmental Disorder Version — 12.7; 8.6 Scores on a scale

Primary: Pediatric Anxiety Rating Scale — 10.94; 13.93 units on a scale

Primary: Change in Mean Length of Utterance (MLU) — 0.5387; 0.2987 Morphemes per utterance — p=<0.555

Primary: Aberrant Behavior Checklist (ABC) - Parent Reported Change — -2.4 score on a scale — p=0.56

Primary: The Effects of rTMS on Reciprocal Social Awareness — 68; 79.667; 64.2; 74 total raw score (higher=worse)

Primary: Number of Confirmed Social Responsiveness Scale (SRS) Responders — 517; 351 participants

Primary: Number of Participants With Improvement on the Clinical Global Impression-Improvement (CGI-I) Scale — 3; 1 Participants

Primary: Change in Social Communication as Measured by the Vineland Adaptive Behavior Scales, Third Edition (VABS-3) — 3.13; 1.98 score on a scale — p=0.83

Primary: Social Responsiveness Scale-2 (SRS-2) Total Score at Baseline — 75.6; 72.6 T-score — p=0.331