N/A
N=44
Services to Enhance Social Functioning in Adults With Autism Spectrum Disorders
Autism · Autism Spectrum Disorder · Autistic Disorder · Asperger Syndrome · Pervasive Developmental Disorder
Bottom Line
View on ClinicalTrials.gov: NCT04788537 ↗Enrolled (actual)
44
Serious AEs
0.0%
Results posted
Mar 2025
Primary outcome: Primary: Reduction in Social Responsiveness Scale, Second Edition (SRS-2) - Adult (Relative/Other Report) — 68.67; 70.41; 66.08; 72.33 Scaled Score — p=.006
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Training to Understand and Navigate Emotions and Interactions (TUNE In) (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- University of Pennsylvania
- Primary completion
- Jun 2023
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Reduction in Social Responsiveness Scale, Second Edition (SRS-2) - Adult (Relative/Other Report) |
68.67; 70.41; 66.08; 72.33 | .006 sig |
Summary
The purpose of this study is to test a novel, three-part cognitive behavioral treatment strategy to improve social functioning in adults with autism spectrum disorder.
The treatment, named TUNE In (Training to Understand and Navigate Emotions and Interactions), includes components to address the many behavioral domains involved in social functioning, including social motivation, social anxiety, social cognition, social skills, and generalization of the skills to community settings.
The Investigators will test the efficacy of TUNE In to improve social functioning in adults with autism spectrum disorder (ASD), using a randomized controlled trial using the SRS-2 as the primary outcome measure.
Eligibility Criteria
Inclusion Criteria
- diagnosis of autism spectrum disorder
Exclusion Criteria
- intellectual disability
- severe mood or psychotic symptoms experienced in the past 4 weeks
- severe self-injurious or aggressive behavior
- severe extrapyramidal motor or sedating side effects of medications
- concomitant participation in another social skills treatment program.
Data sourced from ClinicalTrials.gov (NCT04788537). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.