N/A Completed N=44 Randomized Single-blind Treatment

Services to Enhance Social Functioning in Adults With Autism Spectrum Disorders

Autism Spectrum Disorder · Autistic Disorder · Asperger Syndrome · Pervasive Developmental Disorder

Source: ClinicalTrials.gov NCT04788537 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Mar 2025

Primary outcomePrimary: Reduction in Social Responsiveness Scale, Second Edition (SRS-2) - Adult (Relative/Other Report) — 68.67; 70.41; 66.08; 72.33 Scaled Score — p=.006

Summary

The purpose of this study is to test a novel, three-part cognitive behavioral treatment strategy to improve social functioning in adults with autism spectrum disorder. The treatment, named TUNE In (Training to Understand and Navigate Emotions and Interactions), includes components to address the many behavioral domains involved in social functioning, including social motivation, social anxiety, social cognition, social skills, and generalization of the skills to community settings. The Investigators will test the efficacy of TUNE In to improve social functioning in adults with autism spectrum disorder (ASD), using a randomized controlled trial using the SRS-2 as the primary outcome measure.

Outcome Measures

Outcome	Result	p-value
PRIMARY Reduction in Social Responsiveness Scale, Second Edition (SRS-2) - Adult (Relative/Other Report)	68.67; 70.41; 66.08; 72.33	.006 sig

Eligibility Criteria

Inclusion Criteria

diagnosis of autism spectrum disorder

Exclusion Criteria

intellectual disability
severe mood or psychotic symptoms experienced in the past 4 weeks
severe self-injurious or aggressive behavior
severe extrapyramidal motor or sedating side effects of medications
concomitant participation in another social skills treatment program.

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Data sourced from ClinicalTrials.gov (NCT04788537). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.