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Clinical Trial Search

Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.

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30 closest matches · ranked by relevance

Phase 2 N=30 Sirolimus for Autoimmune Disease of Blood Cells

Autoimmune Pancytopenia · Autoimmune Lymphoproliferative Syndrome (ALPS) · Evans Syndrome
Primary: Number of Participants With Grade 3 and 4 Toxicities of Administration of Oral Sirolimus — 1 participants
Children's Hospital of Philadelphia Results Dec 2017 3.3% serious AE View details

Phase 1 N=36 sPIF CLINICAL STUDY PROTOCOL IN AUTOIMMUNE HEPATITIS

Autoimmune Hepatitis
Primary: Safety/Tolerability Measured by Clinical Laboratory Tests, Metabolics, Cytokines, Anti-PIF Antibody, Periodic Physical Examination, Including Vital Signs Measurements…
Christopher O'Brien, MD Results Nov 2019 0.0% serious AE View details

Phase 2 N=47 Alemtuzumab to Treat Severe Aplastic Anemia

Severe Aplastic Anemia, Refractory · Severe Aplastic Anemia, Relapse
Primary: Number of Participants With Hematological Response at 6 Months — 0; 18 Participants
National Heart, Lung, and Blood Institute (NHLBI) Results Aug 2019 51.1% serious AE View details

Phase 2 N=23 Rituximab to Treat Severe Hemophilia A

Hemophilia A
Primary: Proportion of Subjects With Major Response, i.e. Inhibitor Level Falls to Less Than 5 BU/mL Between Weeks 6 to 22 and Remains Below 5 BU/mL at 5-7 Days Following…
Carelon Research Results Jun 2013 68.8% serious AE View details

Phase 1 N=13 Campath in Chronic GVHD

Chronic Graft-vs.-Host Disease
Primary: The Maximum Tolerated Dose (MTD) of a Four-week Course of Alemtuxumab in Chronic GVHD for Patients With an Incomplete Response to Steroids — 53 mg
Dana-Farber Cancer Institute Results Aug 2013 46.2% serious AE View details