Phase 4 N=1,658 Benign Prostatic Hyperplasia (BPH) Screening Tool Case Finding Study in Subjects >=50 Years
Prostatic Hyperplasia
Primary: Number of Men With Confirmed Diagnosis of BPH — 386; 437 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=21 Prostate Artery Embolization (PAE) for Lower Urinary Tract Symptoms (LUTS) Due to Benign Prostatic Hyperplasia (BPH)
Benign Prostatic Hyperplasia
Primary: Number of Adverse Events Reported — 7 adverse events
Phase 3 N=420 Cetrorelix Pamoate in Patients With Symptomatic Benign Prostatic Hypertrophy (BPH)
Benign Prostatic Hypertrophy
Primary: International Prostate Symptom Score (IPSS) — -6.2; -5.1; -5.7 Units on a scale — p=0.371
N/A N=45 Prostatic Artery Embolization (PAE) for Treatment of Benign Prostatic Hyperplasia (BPH)
Benign Prostatic Hyperplasia (BPH)
Primary: The Primary Objective is to Evaluate the Safety of Prostate Artery Embolization (PAE) for the Treatment of Lower Urinary Tract Symptoms (LUTS) Attributed to Benign…
Phase 3 N=97 A Study in Benign Prostatic Hyperplasia
Benign Prostatic Hyperplasia
Primary: Change From Baseline to 8-Week Endpoint in Arterial Resistive Index (RI) in the Prostate Transition Zone — -0.01; 0.00 ratio — p=0.121
N/A N=28 Prostatic Artery Embolization (PAE) for Treatment of Signs and Symptoms of Benign Prostatic Hyperplasia (BPH) Using Bead Block Microspheres
Benign Prostatic Hyperplasia (BPH)
Primary: Number of Reported Treatment-related Adverse Events (AE) as Assessed by NCI CTCAE Grading Scale . — 6; 10; 0; 0 events — p=0.05
Phase 2 N=15 Prostate Embolization for Benign Prostatic Hyperplasia
Benign Prostatic Hyperplasia
Primary: Number of Participants With Bladder or Rectal Injury — 0 Participants
Phase 3 N=4,844 Benign Prostatic Hyperplasia Trial With Dutasteride And Tamsulosin Combination Treatment
Prostatic Hyperplasia
Primary: Number of Events of Acute Urinary Retention (AUR) or Benign Prostatic Hyperplasia (BPH)-Related Prostatic Surgery at the Indicated Time Periods. — 29; 27; 40; 14 events…
Phase 3 N=511 A Study of Tadalafil in Men With Benign Prostatic Hyperplasia
Benign Prostatic Hyperplasia (BPH)
Primary: Change From Baseline in Total International Prostate Symptom Score (IPSS) at 12 Weeks — -4.2; -6.3; -5.7 units on a scale — p=0.001
N/A N=10 MRI Guided Transrectal Prostate Laser Ablation for Benign Prostatic Hypertrophy (BPH)
BPH · Prostate Hyperplasia · Urinary Frequency/Urgency
Primary: International Prostate Symptom Score (IPSS) Change — -17.5 units on a scale
N/A N=80 BPH-6: Comparison of the UroLift System to TURP for Benign Prostatic Hyperplasia
Benign Prostatic Hyperplasia
Primary: Responder Analysis: A Subject is a Responder at the 12 Month Follow-up Time Point if All 6 Thresholds of the BPH-6 Endpoint Are Met — 52; 20 % Responders of Participants
N/A N=248,393 Benign Prostatic Hypertrophy Treatment Patterns & Outcomes: Marketscan
Prostatic Hyperplasia
Primary: Number of Participants by Treatment Cohort With and Without a Benign Prostatic Hypertrophy (BPH) Diagnosis — 122307; 9456; 3293; 3674 participants
Phase 3 N=1,058 Study of Tadalafil Once-a Day for 12 Weeks in Men With Signs and Symptoms of Benign Prostatic Hyperplasia
Benign Prostatic Hyperplasia
Primary: Change From Baseline to 12 Week Endpoint in International Prostate Symptom Score (IPSS): Primary Analysis — 17.08; 17.30; -2.25; -4.92 units on a scale — p=<0.001
Phase 2 N=92 Transperineal Intraprostatic Injection of PRX302 Under Ultrasound Guidance for Management of Prostatic Hyperplasia
Benign Prostatic Hyperplasia
Primary: Change in International Prostate Symptom Scale (IPSS) of Lower Urinary Tract Symptoms From Baseline to 3 Months (Total Score at 3 Months Minus Total Score at Baseline)…
Phase 2 N=21 Effectiveness of onaBoNT-A vs Oral Tamsulosin in Men With BPH and LUTS
Benign Prostatic Hyperplasia · Lower Urinary Track Symptoms
Primary: American Urologic Association Symptom Score (AUASS) — 18.66; 14.16 score on a scale
N/A N=9 Prostate Artery Embolization for the Treatment of Symptomatic Benign Prostatic Hyperplasia
Prostatic Hyperplasia, Benign · Enlarged Prostate With Lower Urinary Tract Symptoms
Primary: Number of Participants With Adverse Events — 3 Participants
Phase 4 N=232 The Long Term Effects of Alfuzosin(Xatral XL) in Lower Urinary Tract Symptoms(LUTS)/BPH Patients
BPH
Primary: Primary Outcome; International Prostate Symptom Score Changes Between 4 Groups Compared to Baseline After 12 mo Treatment — 13.0; 12.0; 10.6; 13.4 score — p=<0.05
Phase 3 N=528 Cetrorelix Pamoate IM Regimens in Patients With Symptomatic Benign Prostatic Hyperplasia (BPH)
Benign Prostatic Hypertrophy
Primary: IPSS Change From Baseline — -5.6 Units on a scale — p=<0.001
Phase 3 N=325 Study to Treat Patients Who Have Signs and Symptoms of Benign Prostatic Hyperplasia (BPH) With Tadalafil Daily
Benign Prostatic Hyperplasia
Primary: Change From Baseline to 12 Weeks, International Prostate Symptom Score (IPSS) — -5.6; -3.6 Units on a Scale — p=0.004
Phase 2 N=134 Botulinum Toxin Injection for the Management of BPH
Benign Prostatic Hyperplasia
Primary: Improvement in the AUA Symptom Score Index by 30% From Baseline Within the First 12 Weeks After Injection. — 46; 50 participants — p=<0.05
Phase 3 N=253 Dutasteride 0.5mg For The Treatment Of Chinese Patients With Benign Prostatic Hyperplasia (BPH)
Benign Prostatic Hyperplasia · Prostatic Hyperplasia
Primary: Percent Change From Baseline in the Prostate Volume at Month 6 — -17.00; -2.77 percent change in volume — p=<0.0001
Phase 3 N=610 Phase 3 Study of Tadalafil Once-Daily in Asian Men With Benign Prostatic Hyperplasia (BPH)
Benign Prostatic Hyperplasia
Primary: Change From Baseline in Total Score of International Prostate Symptom Score (IPSS) at 12 Weeks — -4.5; -6.0 units on a scale — p=<0.001
Phase 2 N=52 Explorative Study of Degarelix for Treatment of Benign Prostatic Hyperplasia.
BPH
Primary: Testosterone Area Below Baseline Interval — 21.0; 16.0; 54.6; 70.6 ng*days/mL
Phase 3 N=909 A Study of Tadalafil in Men With Benign Prostatic Hyperplasia (BPH) and Erectile Dysfunction (ED)
Benign Prostate Hyperplasia · Erectile Dysfunction
Primary: Change From Baseline in Total International Prostate Symptom Score (IPSS) at Week 12 — -4.08; -5.49; -4.92 units on a scale
Phase 2 N=200 Effects of Tadalafil Once a Day for 12 Weeks in Men With Signs and Symptoms of Benign Prostatic Hyperplasia
Benign Prostatic Hyperplasia
Primary: Change From Baseline to 12 Week Endpoint in Detrusor Pressure at Peak Urinary Flow Rate (PdetQmax) — 54.83; 56.87; 1.92; -2.95 centimeters of water (cm H20) — p=0.068
N/A N=197 Safety and Efficacy Study for the Treatment of BPH (Enlarged Prostate)
Benign Prostatic Hyperplasia · Lower Urinary Tract Symptom
Primary: Efficacy: Change From Baseline in the International Prostate Symptom Score (IPSS) at 3 Month Follow-Up — -11.2; -4.3 Cange in IPSS score
Phase 1 N=24 A Study of Tadalafil in Benign Prostatic Hyperplasia
Benign Prostatic Hyperplasia
Primary: Pharmacokinetics: Area Under the Concentration Curve (AUC) for Tadalafil and Metabolite IC710 — 1410; 1340; 2710; 3410 nanograms*hour/milliliter (ng*hr/mL)
Phase 2 N=404 A Trial of Degarelix in Men With Lower Urinary Tract Symptoms (LUTS) Associated With Benign Prostatic Hyperplasia (BPH)
Lower Urinary Tract Symptoms (LUTS)
Primary: Mean Change in International Prostate Symptom Score (IPSS) — -4.46; -5.65; -6.11; -5.88 percentage change from baseline — p=0.0911
Phase 3 N=461 A New Drug for Benign Prostatic Hyperplasia (BPH) Compared With Placebo
Benign Prostatic Hyperplasia (BPH)
Primary: International Prostate Symptom Score (IPSS) — 21.5; 21.4; -6.5; -3.6 Units on a 0 to 35 scale
Phase 3 N=612 Multinational Study to Evaluate Tadalafil in Asian Men With Signs and Symptoms of Benign Prostatic Hyperplasia
Benign Prostatic Hyperplasia
Primary: Change From Baseline in International Prostate Symptom Score (IPSS) at 12 Weeks — -3.0; -4.8; -4.7; -5.5 Units on a scale — p=0.003