Clinical Trial Search

Primary: Comparison of Log Change of Skin Flora Relative to Pre-treatment (Baseline) in Each of 3 Sampling Sites at a Defined Post-treatment Sampling Time. — -2.19; -1.85; -2.42…

Primary: Relative 16S Abundance - Control Soap — 100; 74; 84; 100 Percentage of Baseline

Primary: Relative Staphylococcus Aureus Abundance — 0.13; 12.2 ratio to baseline S. aureus abundance

Primary: Percent Responder Rates of Bacterial Reduction on the Abdomen and Groin Sites — 80; 75; 86; 65 % of Treated Sites

Primary: Measurement of Skin Flora Recovery Post-prep Application — 1.39; 1.15; 1.97; 1.82 log10 CFU/cm^2 — p=0.13

Primary: Bacterial Colony Forming Units Present on Hand Prints After Time Spent in Common Areas — 2.17; 1.81 log(10) transformed CFU

Primary: Antimicrobial Activity of the Investigational Products Compared to Control. — 3.85; 3.91; 3.87; 3.84 log10 CFU/cm^2

Primary: Percent Responder Rates (%) of Bacterial Reduction on the Abdomen and Groin — 93; 86; 50; 25 Percent of Sites

Primary: Relative GAS Survival — 100; 75; 90 percentage overall bacterial abundance

Primary: Change in Number of Unique Bacterial Isolates From Pre-skin Preparation to Post-CABG - Sternal Site — -1.34; -1.31 isolates — p=0.655

Primary: Number of Participants With Bacterial Growth Before and After Photodynamic Treatment and After Skin Antisepsis — 10; 10; 3; NA Participants

Primary: Measurement of Skin Flora Recovery Post-prep Application Relative to Baseline — 0.91; 2.81; 0.59; 2.96 Log10 CFU/cm^2 — p=<0.0001

Primary: Bacterial Reduction — 4.83; 4.78; 2.23 log10 CFU/cm^2

Primary: Responder Rates (%) of Sites Identified for Bacterial Reduction on the Abdomen and Groin — 78; 84; 54; 56 Percent of sites

Primary: Change in Bacterial Microflora in the Inguinal Area — -3.86; -4.34; -3.65; -3.80 log10 CFU

Primary: Responder Rate — 159; 165; 163; 5 Participants — p=<0.0001

Primary: CLR-transformed Abundance of Any Significant Taxa — 3.29; -2.49; -1.59; -2.75 Relative Abundance

Primary: Change From Baseline in Skin Health, Visual Skin Score (VSS) at 14 Days — 0.1; 0.4 units on a scale

Primary: Number of Subjects With Plasma Levels of Chlorexidine Following Systemic Exposure After a Single Topical Application of CHG. — 0; 0; 0 Participants

Primary: Treatment-associated Change in S. Aureus Colonization During a Typical 10-hour Work Day — -99.8; -13.5 Percent change in colonization — p=<0.01

Primary: Responder Rate — 178; 167; 175; 0 Participants

Primary: Change in Bacterial Microflora on the Inguinal Area — -3.7; -3.1; -3.5 log10 CFU

Primary: Change in the Abundance of Staphylococcus Aureus in the Nose After Decolonization — -781 fg/uL

Primary: Bacterial Reduction — 4.04; 4.01; 1.60 log10 cfu/cm^2

Primary: Change in the Release of Skin Flora From the Hands From Baseline to 5 Minutes After Disinfection by Surgical Scrubbing (Time Frame- "Baseline and 5 Minutes"). — 3.96…

Primary: Number of Positive vs Negative Culture's Based on Skin Prep Method — 6; 6; 12; 11 Participants

Primary: Microbial Community Richness - Baseline (Day 0) — 56.5862069; 32.13043478; 43.72413793; 34.03703704 Number of bacterial taxa — p=0.071225

Primary: Number of Patients With a Positive Propionibacteria Swabs on Day of Surgery After At-Home Washes With Benzoyl Peroxide or Chlorhexidine Gluconate — 25; 24; 14; 11…

Primary: Objective Erythema Assessment Using Clinical Grading Analog Scale — 0.8; 0.83; 0.75; 0.29 score on a scale

Primary: Evaluate the Residual Effect of Chlorhexidine 2% / Isopropyl Alcohol 70% Administered Topically — 24; 48; 24 (CFU/cm2) — p=<0.05