Clinical Trial Search

Primary: Peripheral Vestibular Function (Vestibulo-ocular Reflex/Semicircular Canal): Caloric Weakness — 8.8; 14.7; 12.3; 7.1 percentage of caloric weakness

Primary: Requirement of Oxymetalozine Rescue for Ear Pain During Hyperbaric Therapy Compression — 8; 11 Participants

Primary: Number of Participants Undergoing Acoustic Reflectance — 410; 410 participants — p=<0.05

Primary: Number of Serious Adverse Events — 0 Serious Adverse Event

Primary: Eustachian Tube Dysfunction (ETD) Symptom Visual Analog Scale (VAS) - Total Score — 59.6 score on a scale

Primary: Hearing Handicap Inventory for Adults (HHIA) — 26.20; 37.34; 19.21 Scale score — p=.05

Primary: Number of Blast-exposed Veterans With Abnormal Abilities in One or More Behavioral Tests of Central Auditory Processing — 99.1; 95.2; 96.6; 97.5 units on a scale

Primary: Audiological Test Results — 10.8; 6.6 decibels Hearing Level

Primary: Vestibular "Endolymphatic Hydrops (EH)" — 0; 4; 2 participants

Primary: Change in Static Subjective Visual Vertical (SVV) — 0.69; 0.58; 0.69; 0.89 degrees — p=0.97

Primary: Percentage of Ears Treated Successfully With the TTDS in the Absence of Acute Intraprocedural Adverse Events. — 94.6 percentage of ears

Primary: Latency Between mLVP and mTVP Signals — 127.26 Time in milliseconds

Primary: Changes in the Intracuff Pressure — 3 cmH2O

Primary: Procedural Success: — 103; 91 Participants

Primary: Number of Patients With Tympanic Membrane Closure Following Treatment — 23; 10 Participants

Primary: Primary Efficacy Analysis: Number of Randomized Subjects With Tympanogram Normalization at 6 Weeks — 73; 10 Participants

Primary: Number and Type of Contacts With Health Care Providers — 45; 14; 5; 3 Participants

Primary: Fraction of Middle Ear (ME) Pressure Equilibrated (FGE) — 0.17; 0.24; 0.19; 0.23 ratio — p==0.93

Primary: Change in Middle Ear Effusion Over Four Weeks Following an Episode of Acute Otitis Media — 26; 16; 12; 22 Ears — p=0.02

Primary: Competence Score From the Psychosocial Impact of Assistive Devices Scale (PIADS) — 0.56; .37; .62; .41 units on a scale — p=0.527

Primary: Proportion of Subjects Who Achieved Anesthesia Effectiveness Per Investigator Assessment — 89.9 percentage of subjects

Primary: Change in Inflammation Surface Area. — 100; 100; 43; 135 percentage of the baseline surface

Primary: Skin Irritation — 0.22; 0.20; 0.13; 0.11 score on a scale

Primary: Number of Subjects With Complete Normalization of Abnormal Tympanometry, Regardless of Additional Treatment — 7; 12 participants — p=0.18

Primary: Device Success — 21 devices

Primary: Safety of Tympanostomy Tube (TT) Delivery System — 0.0 percentage of ears

Primary: Percentage of Ears in Which an Ear Tube Was Successfully Delivered Across the Tympanic Membrane — 393 Ears

Primary: Tinnitus Functional Index — 69.9; 68.2; 47.8; 66.8 units on a scale — p=<.0001

Primary: Blast Explosive Waves Experienced During the Training — 4.11; 4.29; 4.20; 4.0 number of blasts

Primary: Otoscopic Examination: Auricle and Meatus — 1 ears