Clinical Trial Search

Primary: Binge (Loss-of-control) Eating Episode Frequency — 1.52; 6.05 episodes of behavior — p=.01

Primary: Weight Loss — 0; 0; -2.13; -2.15 percentage of weight loss

Primary: Feasibility - Usage Rating Profile - Intervention — 5.44; 5.53 score on a scale

Primary: Frequency and Severity of Suicidal Ideation Using the Columbia-suicide Severity Rating Scale (C-SSRS) — 515; 7; 3; 1 Participants

Primary: Frequency of Binge Eating in the Past 28 Days — 16.06; 14.48; 6.26; 7.40 days

Primary: Binge Eating Frequency (Continuous) — 0.8; 12.1 Eating events/28 days — p=.0002

Primary: Binge Eating Frequency (Continuous) — 4.4; 3.0 binge eating days (out of 28)

Primary: Frequency of Binge Eating Episodes — 0.8; 1.0 episodes/week

Primary: Binge Eating Frequency (Continuous) — 9.90; 7.63; 3.30; 1.97 binge-eating episodes per month — p=0.0001

Primary: Binge Eating (Remission) — 10; 8; 6; 6 participants — p=0.60

Primary: Change in Number of Binge Eating Episodes — .93; .76 binge eating episodes

Primary: Change in Eating Disorder Examination-Self-report Questionnaire (EDE-Q) — 3.18; 2.89; 2.81; 2.13 score on a scale

Primary: Change From Baseline to Week 12 in the Number of Binge Eating (BE) Days Per Week — -2.93; -2.93 BE days per week — p=0.9992

Primary: Recruitment Rate — 30 Participants

Primary: Change From Baseline in Log Transformed Binge Days Per Week at Week 11 — -1.23; -1.24; -1.49; -1.57 Log days — p=0.8825

Primary: Number of Subjects Who Reached Binge Eating Remission — 16; 65 participants

Primary: Change From Baseline in the Number of Binge Days Per Week at Visit 8 Which Spans Weeks 11/12 — -2.26; -3.92 Binge days per week — p=<0.001

Primary: Change From Baseline in the Number of Binge Days Per Week at Visit 8 (Weeks 11-12) — -2.51; -3.87 Binge days per week — p=<0.001

Primary: Change in Binge Eating Frequency — 6.4; 5.4 binge-eating episodes per month — p=.44

Primary: Change in Binge-Eating Frequency — -14; -17.00 episodes per past 28 days

Primary: Binge-Eating Frequency — 2.95; 2.33; 0.96 Binge-eating episodes (past 28 days)

Primary: Brain Activation Associated With P(Stop) — 0.02; 0.11; 0.04; 0.05 BOLD Signal

Primary: Binge Eating Frequency (Continuous) — 0.86; 3.25 binge eating days per month — p=.07

Primary: Change From Baseline in Number of Binge Eating Days Per Week — -3.44; -3.07; -3.01 binge eating days per week — p=0.1893

Primary: Number of Modified Intent-to-Treat Patients With Binge-eating Abstinence — 2; 1; 5; 4 Participants — p=0.36

Primary: Change From Baseline in Binge Eating Scale (BES) at 4 Weeks, 3 Months and 6 Months — 17.38; 15.45; 10.52; 13.52 units on a scale

Primary: Change in Binge Eating Sum Score — -0.60; 0.89 score on a scale

Primary: Blood Oxygen Level-dependent (BOLD) Functional Magnetic Resonance Imaging (fMRI) Response to Food-specific Stop-signal Task — -0.4; -0.3 percent signal change

Primary: Binge-Eating Relapse — 3; 5 Participants

Primary: Compliance With Study Requirements: Attendance at Treatment Sessions — 5; 3 participants