N/A N=1,212 Disrupt CAD III Post-Approval Study (PAS)
Coronary Artery Disease · Myocardial Infarction
Primary: All-cause Death Rate — 3 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=1,014 Clinical Evaluation of the CADence Device in Detection of Coronary Artery Diseases
Coronary Artery Disease
Primary: Sensitivity and Specificity of CADence to Detect Stenosis Relative to SPECT Performance, Using Either CT or Standard Angiogram as the Gold Standard — 78; 36 percent…
N/A N=431 Disrupt CAD III With the Shockwave Coronary IVL System
Coronary Artery Disease · Myocardial Infarction
Primary: Number of Participants Who Experienced Freedom From Major Adverse Cardiac Events (MACE) Within 30 Days Post-procedure — 92.2 percentage of participants
N/A N=101 Angiographic Comparison in an Observational Study of CADence (The AMBIENCE Study)
Coronary Artery Disease
Primary: Percent of Participants With Positive Agreement of CADence Device Under Normal Use Conditions as Compared to Coronary Angiograms as Accurate and Appropriate — 101; 31…
Phase 3 N=426 Gadobutrol/Gadavist-enhanced Cardiac Magnetic Resonance Imaging (CMRI) to Detect Coronary Artery Disease (CAD)
Coronary Artery Disease
Primary: Presence of a Myocardial Perfusion Defect Indicating Significant CAD Per Participant on Gadobutrol-enhanced CMRI (Based on RPS) - Primary Analysis of Sensitivity Based…
Phase 3 N=478 Gadobutrol / Gadavist-enhanced Cardiac Magnetic Resonance Imaging (CMRI) to Detect Coronary Artery Disease (CAD)
Coronary Artery Disease
Primary: Presence of a Myocardial Perfusion Defect Indicating Significant CAD Per Participant on Gadobutrol-enhanced CMRI - Primary Analysis of Sensitivity Based on Blinded…
N/A N=123 Cadence and Intensity in Children and Adolescents (CADENCE-KIDS)
Healthy
Primary: Cadence - Steps Per Minute — 128.4; 116.5; 106.6; 101.3 Cadence - Steps per Minute
N/A N=306 Data Acquisition for Optimization of Coronary Artery Disease (CAD) Algorithm
Coronary Artery Disease
Primary: The Area Under the Receiver Operating Characteristic Curve of the CAD-score to Separate CAD From Non-CAD Patients. — 73.4 percentage of 100
N/A N=1,410 Gastroenterology Artificial INtelligence System for Detecting Colorectal Polyps (The GAIN Study)
Colon Adenoma · Colon Polyp · Colon Lesion
Primary: Difference in Adenomas Per Colonoscopy (APC) — 0.60; 0.74 Resected adenomas — p=0.0002
Phase 2 N=129 AZD5718 Phase IIa Study to Evaluate Efficacy, Safety and Tolerability of Oral AZD5718 in Patients With Coronary Artery Disease (CAD).
Coronary Artery Disease
Primary: Change From Baseline in Creatinine-normalized u-LTE4 at Week 4 — 0.04; 0.09; 1.09 Ratio — p=<0.001
N/A N=739 CADDIE Trial - Computer Aided Diagnosis and Detection for Intelligent Endoscopy
Polyps · Adenoma Colon · Colorectal Polyp
Primary: To Evaluate Whether Using the CADDIE System Improves Endoscopist Detection of Adenomas During Colonoscopy. — 33.30; 25.20 ADR (% of participants)
N/A N=68 Clinical Performance of Chairside CAD/CAM Restorations
Dental Cements · Caries,Dental
Primary: Functional Long-term Properties Clinical Performance of Restorations (Onlays and Crowns) [Retention Scores] — 40; 40; 0; 0 Restorations
N/A N=30 Computer Assisted Instrument Guidance (CAIG) For Arterial Line Placement
Arterial and Midline Catheterization
Primary: Time Needed to Correctly Insert the Arterial or Midline Catheter. — 30.07; 44.76 Seconds
N/A N=105 Randomized Investigation of Chest Pain Diagnostic Strategies
Acute Coronary Syndrome · Chest Pain
Primary: The Composite of Revascularization, Re-hospitalization, and Recurrent Cardiac Testing Through 90 Days. — 7; 20 participants
N/A N=72 Disrupt CAD IV With the Shockwave Coronary IVL System
Coronary Artery Disease · Myocardial Infarction
Primary: Percentage of Participants Who Experienced Freedom From MACE Within 30 Days Post-procedure — 93.8 percentage of participants
N/A N=25 Breast Cup Immobilization Device II (GCC 1047)
Breast Cancer
Primary: Breast Cup Immobilization Device II (GCC 1047) Feasibility — 25 Participants
Phase 4 N=1,097 A Carotid Stenting Boston Scientific Surveillance Program
Carotid Artery Disease
Primary: Composite of Major Adverse Events (MAE) Defined as Center-reported and Clinical Events Committee (CEC) Adjudicated Death, Stroke, and Myocardial Infarction (MI) — 47…