Clinical Trial Search

Primary: Annualized LRNC Volume Change in Carotid Plaque Composition, as Assessed by MRI — -4.6; -15.1; -9.4 mm^3/year

Primary: Number of Subjects Who Completed All of the Ultrasound Examinations — 17; 37 Participants

Primary: Composite Cognitive Score — 45.5; 47.9 units on a scale

Primary: Uptake of [F-18] RGD-K5 by Carotid Plaque With PET/MRI Imaging in the Artery Believed to be the Cause of Transient Ischemic Attack (TIA) or Stroke Symptoms Compared to…

Primary: Number of Participants Stratified as Non-Index Culprit Lesion Related Major Adverse Cardiac Events (NC-MACE) or No NC-MACE and Association With maxLCBI4mm as a…

Primary: Change in Mean of Wall Volume of Internal Carotid Arteries — -3.52; -5.91 Other - mm^3 ( cubic millimeter )

Primary: Composite Score of Plaque Inflammation/Stability Gene Expression as Assayed by Ribonucleic Acid (RNA) Taqman Analysis — 1.36; 0.82 Cycle threshold (Ct) — p=0.811

Primary: Number of Participants Analyzed for Coronary Calcium Burden by AGS — 9; 11 Participants

Primary: Measurement Bias of Calcification Analyzed by vascuCAP™ Non-invasively Relative to Histopathology as Ground Truth. — -0.47; .07 mm2

Primary: Analysis of Bacterial Types in Plaques — 2.2; 0.58 percentage

Primary: Change in Montreal Cognitive Assessment (MoCA) Score — 0.56; 1.38; -0.75; 0.50 score on a scale

Primary: Comparison of Total Plaque Volume — 0.91 Pearson's correlation statistic

Primary: Change in Oral Plaque — -1.05; -0.03 log(percentage) — p=0.001

Primary: Change in Necrotic Core Volume — 0.07 mm^2

Primary: CT Angiography Plaque — 0.17; -1.53 percent change of low attenuation plaque

Primary: Carotid Procedure and Device Related Adverse Events to Determine Device Performance — 53; 10; 1; 2 Device related adverse events

Primary: Radical Peripapillary Capillaries Vessel Density — 55.95; 57.24 percentage of vessel

Primary: Absolute Change From Baseline in Minimum FCT — 21.5; 42.7 µm — p=0.015

Primary: Plaque Inflammation — 1.59; 1.63 SUV

Primary: Percent Cross-sectional Area of Macrophages in Plaque Tissue — 8.08; 8.19 Percent Area — p=0.97

Primary: Changes in Plaque Architecture and Composition Directly Measured by Magnetic Resonance Imaging (MRI) in the Aorta and Carotid Arteries — 7; 5 percentage of internal…

Primary: Change in Minimal Fibrous Cap Thickness (FCT) — 70.9; 97.7 µm

Primary: Kaplan-Meier Estimate of Freedom From the Composite of Any Death, Stroke and MI During the 30 Day Post Procedural Period (DSMI), Plus Fatal and Non-fatal Ipsilateral…

Primary: Percent Change From Baseline in Mean Wall Thickness — 4.245; 6.679 Percent Change

Primary: Incidence of Ipsilateral New White Lesions, by Patient — 12 Participants

Primary: Change in Noncalcified Coronary Artery Plaque Volume (NCPV) — -45 mm^3

Primary: Percent Reduction From Baseline in TBRmeanmax of the Qualifying Segment — 1.4; 5.8 Percent reduction — p=0.006

Primary: Any Periprocedural Stroke, Myocardial Infarction, or Death During a 30-day Peri-procedural Period, and Postprocedural Ipsilateral Stroke Thereafter, up to 4-years…

Primary: Number of Participants With First Occurrence of Any Component of the Composite of Major Adverse Cardiovascular Events (Cardiovascular [CV] Death, Non-fatal Myocardial…

Primary: Rate of Change in Mean Posterior-wall Carotid Intima-media Thickness (cIMT) — -0.006; 0.000 mm/year — p=0.220