Clinical Trial Search

Primary: Annualized LRNC Volume Change in Carotid Plaque Composition, as Assessed by MRI — -4.6; -15.1; -9.4 mm^3/year

Primary: Composite Cognitive Score — 45.5; 47.9 units on a scale

Primary: Change in Montreal Cognitive Assessment (MoCA) Score — 0.56; 1.38; -0.75; 0.50 score on a scale

Primary: Measurement Bias of Calcification Analyzed by vascuCAP™ Non-invasively Relative to Histopathology as Ground Truth. — -0.47; .07 mm2

Primary: Number of Subjects Who Completed All of the Ultrasound Examinations — 17; 37 Participants

Primary: Radical Peripapillary Capillaries Vessel Density — 55.95; 57.24 percentage of vessel

Primary: Changing LDL Cholesterol — 100; 70 Mg/dl

Primary: Uptake of [F-18] RGD-K5 by Carotid Plaque With PET/MRI Imaging in the Artery Believed to be the Cause of Transient Ischemic Attack (TIA) or Stroke Symptoms Compared to…

Primary: Change in Mean of Wall Volume of Internal Carotid Arteries — -3.52; -5.91 Other - mm^3 ( cubic millimeter )

Primary: Composite Score of Plaque Inflammation/Stability Gene Expression as Assayed by Ribonucleic Acid (RNA) Taqman Analysis — 1.36; 0.82 Cycle threshold (Ct) — p=0.811

Primary: Evidence of Carotid Artery or Intracranial Artery Atherosclerosis Confirmed by Vascular Ultrasonography — 96; 1063; 826; 241 artery numbers

Primary: Ipsilateral Ischemic Stroke Before Carotid Endarterectomy — 33 participants

Primary: Kaplan-Meier Estimate of Freedom From the Composite of Any Death, Stroke and MI During the 30 Day Post Procedural Period (DSMI), Plus Fatal and Non-fatal Ipsilateral…

Primary: Percent Cross-sectional Area of Macrophages in Plaque Tissue — 8.08; 8.19 Percent Area — p=0.97

Primary: Table 1 Study Specific Characteristic Part One — 69.8; 59.8; 59.1; 72.7 Percentage of Participants — p=>0.05

Primary: Analysis of Bacterial Types in Plaques — 2.2; 0.58 percentage

Primary: Stroke or Death in the Territory of Qualifying Artery — 5 Participants — p=0.08

Primary: Carotid Procedure and Device Related Adverse Events to Determine Device Performance — 53; 10; 1; 2 Device related adverse events

Primary: Annualized Rate of Change in Mean of the Maximum (MeanMax) CIMT Measurements From Each of the 12 Carotid Artery Sites Based on All Scans Performed During the 104-Week…

Primary: Number of Participants Analyzed for Coronary Calcium Burden by AGS — 9; 11 Participants

Primary: Incidence of Ipsilateral New White Lesions, by Patient — 12 Participants

Primary: Percentage of Patients Having a Significant Change in Neuropsychometric Performance After Carotid Endarterectomy — 22; 4.5 percentage of participants

Primary: Change in Necrotic Core Volume — 0.07 mm^2

Primary: C-Reactive Protein (CRP) — 3.7; 4.6 mg/L

Primary: Number of Participants Who Experienced Major Adverse Events (MAE) at One Year — 11 Participants — p=<0.00001

Primary: The Composite of Cerebral Ischemic Stroke and Transient Ischemic Attack — 0; 0; 0; 1 Participants — p=0.462

Primary: CT Angiography Plaque — 0.17; -1.53 percent change of low attenuation plaque

Primary: Any Periprocedural Stroke, Myocardial Infarction, or Death During a 30-day Peri-procedural Period, and Postprocedural Ipsilateral Stroke Thereafter, up to 4-years…

Primary: Mean Coronary Wall Thickness — 2.0 mm

Primary: Percent Change in Cerebral Blood Flow (CBF) — 0; 25 percentage increase in CBF