N/A N=8 Peripheral Sensory Input in Central Post Stroke Pain (CPSP)
Central Post Stroke Pain
Primary: Reduction in Spontaneous Pain Intensity After a Peripheral Nerve Block. — 6.5; 0.0 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=220 Efficacy Of Pregabalin In Subjects With Post-Stroke Central Neuropathic Pain
Central Neuropathic Pain
Primary: Mean Pain Score at Endpoint as Measured by Daily Pain Rating Scale (DPRS) — 4.8; 5.0 scores on scale — p=0.578
Phase 1 N=9 TMS and Exercise for Post-stroke Pain
Chronic Post-stroke Headache
Primary: Change in Modified Rankin Scale From Baseline to Follow-up 30 Days After Last Intervention — 0; 1 units on a scale — p=0.896
N/A N=96 Multimodal Treatment for Hemiplegic Shoulder Pain
Stroke · Shoulder Pain
Primary: Brief Pain Inventory (BPI)- Short Form (SF) Question 3 (BPI-SF3) - Mean Change From Baseline — 7.1; 7.4; 8.1; -2.8 units on a scale
N/A N=28 Electrical Stimulation for the Treatment of Post-Stroke Shoulder Pain
Shoulder Pain
Primary: Pain Intensity (Trial Stage) — 8.2; 6.1; 5.0; 2.1 score on a scale
N/A N=25 Electrical Stimulation for Hemiplegic Shoulder Pain
Stroke · Shoulder Pain
Primary: Brief Pain Inventory Short Form — 7.5; 7.6; 6.1; 6.8 units on a scale — p=0.04
N/A N=88 Electrical Stimulation for the Treatment of Chronic Post-Stroke Shoulder Pain Using the Smartpatch System
Post-stroke Shoulder Pain · Hemiplegic Shoulder Pain
Primary: Change From Baseline Shoulder Pain Intensity at End of Treatment (EOT) — 7.1; 6.6; 4.1; 4.1 scores on a scale
N/A N=16 Postoperative Peripheral Nerve Stimulation for Management of Post-amputation Pain
Phantom Limb Pain · Postoperative Pain · Neuroma
Primary: Average Phantom Limb Pain (PLP) Score — 4.1; 3.1; 2.2; 3.0 score on a scale
Phase 4 N=16 Pathophysiology of Post Amputation Pain
Amputation Stumps · Neuroma
Primary: Change in Pain — -0.3; -2; -1; 1.3 units on a scale
Phase 4 N=368 P4 (Pregabalin for Peripheral Posttraumatic Pain)
Neuralgia
Primary: Weekly Mean Pain Score at End of Treatment (Week 8) From Daily Pain Diary — 4.61; 5.23 score on a scale — p=0.010
Phase 2 N=16 An Implantable Microneuromodulator for the Treatment of Chronic Shoulder Pain in Chronic Post-Stroke Subjects
Shoulder Pain Chronic
Primary: Relief of Chronic Shoulder Pain — 0; 0 participants
N/A N=7 Percutaneous Peripheral Nerve Stimulation (Neuromodulation) for Postoperative Analgesia
Postoperative Pain
Primary: Change From Baseline of Surgical Site Pain Level (NRS) at Rest [Percentage of Baseline Pain] — 64; 100; 55; 69 percentage of baseline
N/A N=575 Persistent Pain After CS Delivery
Persistent Pain After Delivery
Primary: Persistent Pain-PERCEIVED STRESS Scores Stratified by the Rate of Recovery — 11.4; 12.9; 15.4 units on a scale — p=<0.01
N/A N=15 Post-stroke Pain taVNS
Stroke · Pain
Primary: Thermal Pain Threshold — 41.84; 42.51 Celsius
N/A N=23 Peripheral Nerve Stimulation for Shoulder Pain: Dose Response
Stroke · Shoulder Pain
Primary: Brief Pain Inventory (BPI)- Short Form (SF) Question 3 (BPI-SF3) — 5.6; 6; 5.67; 6.5 score on a scale
N/A N=33 Electrical Stimulation for the Treatment of Post-Amputation Pain Using the SPRINT System
Post-Amputation Pain · Phantom Limb Pain · Residual Limb Pain
Primary: Proportion of Group 1 (Treatment) and Group 2 (Control) Subjects That Achieved ≥ 50% Reduction in All Qualifying Areas of Pain in the First 4 Weeks of Treatment — 7; 2…
Phase 3 N=65 An Implantable Spinal Cord Stimulation Pain Management System
Chronic Pain · Pain, Intractable · Pain
Primary: Change in Visual Analog Scale (VAS) Score From Baseline to 2 Week Post Initial Fitting. — 35 participants with > 50% VAS improvement
N/A N=4 Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment of Post-Stroke Spasticity
Spasticity
Primary: Change From Baseline Contralesional Corticospinal Excitability — 67.88; -37.23 microVolts
N/A N=4 Epidural Spinal Cord Stimulation for Sensory Restoration and Phantom Limb Pain in Upper-Limb Amputees
Phantom Limb
Primary: Stimulation Thresholds to a Variety of Stimulus Parameters — 2.13 milliamps
N/A N=22 Combined Brain and Peripheral Nerve Stimulation for Stroke
Stroke
Primary: Active Range of Motion of Wrist Extension in the Paretic Side — 37.8; 38; 37.2; 38 degrees
N/A N=44 Suicide Prevention for Patients With Chronic Pain
Suicide · Chronic Pain
Primary: Social Problem-solving Inventory - Patient Report — 8.12; 3.64 score on a scale
Phase 3 N=140 Evaluation in the Treatment of Neuropathic Pain Post Breast Surgery
Breast Cancer Patient
Primary: Change in Neuropathic Pain Score at 2 Months (Numeric Rating Scale 0-10) — 4.1; 4.6 units on a scale
Phase 3 N=103 An Open-Label Long-Term Study Of Pregabalin For The Treatment Of Central Neuropathic Pain
Spinal Cord Diseases · Spinal Cord Injuries · Neuralgia
Primary: Number of Participants With Peripheral Edema — 5; 9; 2; 0 Participants
Phase 2 N=28 Subacromial Corticosteroid Injection for Hemiplegic Shoulder Pain
Shoulder Pain
Primary: BPI 12 (Brief Pain Inventory, Question 12) Pain Questionnaire — -1.7; -2.2; -4.7 units on a scale — p=0.16
N/A N=96 Altering Activation Patterns Post-stroke
Stroke · Muscle Spasticity · Hemiparesis
Primary: Change in Mean Completion Time for Graded Wolf Motor Function Test (GWMFT) — -3.66; -0.51; -4.00; -3.89 Seconds
N/A N=65 Ultrasound-Guided Percutaneous Peripheral Nerve Stimulation: A Department of Defense Funded Multicenter Pilot Study
Rotator Cuff Repair · Anterior Cruciate Ligament Reconstruction · Ankle Arthrodesis or Arthroplasty
Primary: Opioid Consumption During First Postoperative Week — 5.0; 47.5 mg
N/A N=27 Spinal Cord Stimulation in Patients With Post-Laminectomy Syndrome in Testing Phase
Laminectomy · Post-laminectomy Syndrome · Spinal Cord Syndrome
Primary: Comparing Visual Analogue Scale (VAS) — 9.3; 8.6; 5.7; 4.9 score on a scale — p=0.112
N/A N=4 Finding an Optimal Latency for Paired Associative Stimulation in People With Chronic Stroke
Stroke
Primary: Change in Cortical Excitability Using Single TMS Pulses — -.07667; 0.11; -.05667; .1233 Log10(microvolts)
Phase 3 N=542 Placebo-controlled Safety and Efficacy Study of Pregabalin in Subjects With Post-traumatic Peripheral Neuropathic Pain
Neuropathic Pain
Primary: Baseline Mean Pain Score — 6.41; 6.54 units on a scale
N/A N=38 Project Relief: Developing Brain Stimulation as a Treatment for Chronic Pain
Chronic Pain · Chronic Lower Back Pain · Back Pain
Primary: Changes in Patient Reported Pain and Discomfort — 47; 13; -30; -18 percent change from baseline