N/A N=8 Peripheral Sensory Input in Central Post Stroke Pain (CPSP)
Central Post Stroke Pain
Primary: Reduction in Spontaneous Pain Intensity After a Peripheral Nerve Block. — 6.5; 0.0 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=65 An Implantable Spinal Cord Stimulation Pain Management System
Chronic Pain · Pain, Intractable · Pain
Primary: Change in Visual Analog Scale (VAS) Score From Baseline to 2 Week Post Initial Fitting. — 35 participants with > 50% VAS improvement
N/A N=575 Persistent Pain After CS Delivery
Persistent Pain After Delivery
Primary: Persistent Pain-PERCEIVED STRESS Scores Stratified by the Rate of Recovery — 11.4; 12.9; 15.4 units on a scale — p=<0.01
Phase 4 N=280 Pain Response Evaluation of a Combined Intervention to Cope Effectively
Chronic Pain
Primary: Brief Pain Inventory (BPI) Total Pain Severity — 6.1; 5.7; 5.8 score on a scale
Phase 2 N=149 Chronic Pain Master Protocol (CPMP): A Study of LY3016859 in Participants With Chronic Low Back Pain
Chronic Low-back Pain
Primary: Change From Baseline for Average Pain Intensity as Measured by the NRS — -1.57; -2.09 score on a scale
N/A N=44 Suicide Prevention for Patients With Chronic Pain
Suicide · Chronic Pain
Primary: Social Problem-solving Inventory - Patient Report — 8.12; 3.64 score on a scale
N/A N=850 Pain Program for Active Coping & Training
Chronic Non-malignant Pain
Primary: Pain Impact Assessed Using the 4-Item Version of Brief Pain Inventory-Short Form ("PEGS") — 6.485; 6.645; 5.486; 6.210 score on a scale
N/A N=440 Acupuncture for Chronic Prostatitis/Chronic Pelvic Pain Syndrome
Chronic Prostatitis With Chronic Pelvic Pain Syndrome
Primary: Proportion of Responders at the End of 8-week — 60.6; 36.8 percentage of participants
N/A N=158 Central Nervous System Amplification in Lumbar Failed Back Surgery Syndrome
Chronic Pain
Primary: Clinical Pain Severity - 50% Reduction Responders vs Nonresponders — -83; 0 percentage of change
Phase 2 N=153 Chronic Pain Master Protocol (CPMP): A Study of LY3556050 in Participants With Chronic Low Back Pain
Chronic Low-back Pain
Primary: Change From Baseline for Average Pain Intensity as Measured by the Numeric Rating Scale (NRS) — -1.69; -1.77 score on a scale
Phase 2 N=159 Chronic Pain Master Protocol (CPMP): A Study of LY3526318 in Participants With Chronic Low Back Pain
Chronic Low-back Pain
Primary: Change From Baseline for Average Pain Intensity as Measured by the Numeric Rating Scale (NRS) at Week 4 — -1.28; -0.90 score on a scale
Phase 4 N=353 Chronic Pain Risk Associated With Menstrual Period Pain
Cystitis, Interstitial · Dysmenorrhea · Migraine Disorders
Primary: Change in Participant Bladder Pain Sensitivity From Baseline. — 38.2; 37.0; 41.2; 47.9 score on a scale — p=.02
Phase 2 N=138 A Chronic Pain Master Protocol (CPMP): A Study of LY3857210 in Participants With Chronic Low Back Pain
Chronic Low-back Pain
Primary: Change From Baseline for Average Pain Intensity as Measured by the Numeric Rating Scale (NRS) — -1.24; -1.63 score on a scale
N/A N=217 An Evaluation of MBSR and CBT for Veterans With Chronic Pain
Chronic Pain · Pain
Primary: Pain Interference Subscale of Brief Pain Inventory (BPI) — 4.7; 4.8; 4.9; 4.4 score on a scale
N/A N=137 Chronic Pain OneSheet Clinical Trial
Chronic Pain
Primary: Pain and Function Goal-setting — 0.0081; 0.0016; 0.0364; 0.0283 Proportion of patient visits — p=<0.05
Phase 2 N=240 Prospective, Randomized Controlled Trial on Perioperative Pregabalin to Reduce Late-onset CRPS After TKA
CRPS
Primary: Epidural Medication Consumption Rate — 6.40; 5.77 mL/h — p=0.003
N/A N=36 Virtual Reality Guided Imagery for Chronic Pain
Complex Regional Pain Syndromes · Back Pain
Primary: Number of Participants Who Are Recruited But Not Enrolled as Documented in Participant Log — 60 Participants
N/A N=30 Brief Cognitive Behavioral Therapy for Chronic Pain
Chronic Pain · Musculoskeletal Pain
Primary: West Haven-Yale Multidimensional Pain Inventory - Interference (WHYMPI-I) to Assess Change at Follow up — 3.43; 3.10 units on a scale — p=.486
N/A N=21 Transcranial Alternating Current Stimulation in Back Pain- Pilot Sudy
Chronic Low Back Pain
Primary: Change in Heart Rate Variability Before and After 40-minute Stimulation — 0.206; -0.01 ms^2 — p=.319
N/A N=78 Optimizing Psychosocial Treatment of Interstitial Cystitis/Bladder Pain Syndrome
Chronic Interstitial Cystitis · Bladder Pain Syndrome · Cystitis, Interstitial
Primary: Change in the Genitourinary Pain Index (GUPI) 2 Months — 6.6; 4.8 score on a scale
Phase 3 N=324 Efficacy & Safety Study of Pregabalin to Treat Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)
Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)
Primary: Decrease in the NIH-CPSI Total Score by at Least 6 Points — 103; 38 Participants
N/A N=105 NEPAL (Neuromodulatory Examination of Pain and Mobility Across the Lifespan)
Musculoskeletal Pain · Pain, Chronic
Primary: Short Physical Performance Battery (SPPB) — 10.95; 10.82; 11.75 score on a scale — p=0.0561
N/A N=74 Sleep Disordered Breathing and Chronic Pain
Sleep Apnea Syndromes
Primary: Number of Sleep Related Events Per Hour — 38.8; 17.4; 4.5; 7.6 events/hour — p=<0.001
N/A N=38 Project Relief: Developing Brain Stimulation as a Treatment for Chronic Pain
Chronic Pain · Chronic Lower Back Pain · Back Pain
Primary: Changes in Patient Reported Pain and Discomfort — 47; 13; -30; -18 percent change from baseline
N/A N=57 Chronic Pain Self-management for Older Adults With Cognitive Impairment: A Randomized Pilot Trial
Chronic Pain · Cognitive Impairment
Primary: Change in Pain Interference — -0.9; 0.2 units on a scale
N/A N=25 Cognitive-behavior Therapy for MS-Related Chronic Pain
Multiple Sclerosis
Primary: Pain Intensity — 5.31; 5.42 units on a scale — p=.911
Phase 2 N=17 An Open-Label Study of CC-10004 for Chronic Prostatitis/Chronic Pelvic Pain Syndrome
Prostatitis · Chronic Prostatitis With Chronic Pelvic Pain Syndrome
Primary: Global Response Assessment — 2 participants
Phase 4 N=72 Interstitial Cystitis: Examination of the Central Autonomic Network
Interstitial Cystitis/Painful Bladder Syndrome · Myofascial Pelvic Pain
Primary: Total Score on Genitourinary Pain Index (GUPI) Scale — 24.4; 22.2; 2.35; 29.25 score on a scale
N/A N=69 Novel Web-based, Self-directed Intervention for Chronic Pelvic Pain
Chronic Pelvic Pain · Endometriosis
Primary: Patient Reported Outcomes Measurement Information System (PROMIS) Pain Interference Short Form (SF) 4a Between Groups — 59.2; 63.4 t-scores — p=0.038
Phase 2 N=41 D-cycloserine in the Management of Chronic Low Back Pain
Low Back Pain · Pain
Primary: Change in Numeric Rating Scale (NRS-11) — -2.47; -1.55 units on a scale