N/A N=575 Persistent Pain After CS Delivery
Persistent Pain After Delivery
Primary: Persistent Pain-PERCEIVED STRESS Scores Stratified by the Rate of Recovery — 11.4; 12.9; 15.4 units on a scale — p=<0.01
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=16 Postoperative Peripheral Nerve Stimulation for Management of Post-amputation Pain
Phantom Limb Pain · Postoperative Pain · Neuroma
Primary: Average Phantom Limb Pain (PLP) Score — 4.1; 3.1; 2.2; 3.0 score on a scale
N/A N=8 Peripheral Sensory Input in Central Post Stroke Pain (CPSP)
Central Post Stroke Pain
Primary: Reduction in Spontaneous Pain Intensity After a Peripheral Nerve Block. — 6.5; 0.0 units on a scale
N/A N=7 Percutaneous Peripheral Nerve Stimulation (Neuromodulation) for Postoperative Analgesia
Postoperative Pain
Primary: Change From Baseline of Surgical Site Pain Level (NRS) at Rest [Percentage of Baseline Pain] — 64; 100; 55; 69 percentage of baseline
N/A N=55 Pain and Function After Orthopedic Surgery
Chronic Pain
Primary: Self-reported Pain Intensity — 3 units on a scale
N/A N=54 Pre-op Cognitive Behavior Therapy to Decrease Chronic Post-Surgical Pain in TKA
Chronic Post-Surgical Pain
Primary: Preoperative Chronic Pain Severity — 4.6; 4.4 units on a scale
N/A N=86 Pregabalin for the Treatment of Pain After Posterior Spinal Fusions
Lumbar Spinal Fusions
Primary: Patient Controlled Analgesia (PCA) Hydromorphone Usage — 44; 39 mL
Phase 3 N=140 Evaluation in the Treatment of Neuropathic Pain Post Breast Surgery
Breast Cancer Patient
Primary: Change in Neuropathic Pain Score at 2 Months (Numeric Rating Scale 0-10) — 4.1; 4.6 units on a scale
N/A N=69 High Pain Intervention in Cesarean Sections
Other Chronic Postoperative Pain
Primary: Severity of Acute Pain — 46; 31 mm — p=0.05
N/A N=26 Surgical Treatment of Post-surgical Mastectomy Pain Utilizing the Regenerative Peripheral Nerve Interface
Post-Mastectomy Chronic Pain Syndrome
Primary: Change in Pain Level — 6.9; 0.6; 4.4; 2.5 score on a scale
N/A N=122 Percutaneous Auricular Neuromodulation for Postoperative Analgesia
Postoperative Pain, Acute
Primary: AVERAGE Pain Measured With the Numeric Rating Scale First 5 Postoperative Days — 1; 3 units on a scale
N/A N=65 Ultrasound-Guided Percutaneous Peripheral Nerve Stimulation: A Department of Defense Funded Multicenter Pilot Study
Rotator Cuff Repair · Anterior Cruciate Ligament Reconstruction · Ankle Arthrodesis or Arthroplasty
Primary: Opioid Consumption During First Postoperative Week — 5.0; 47.5 mg
N/A N=423 Neuropathic Pain After Orchidectomy and Sex Reassignment Surgery
Neuropathic Pain · Phantom Pain · Sex Reassignment Surgery
Primary: Incidence of Phantom Pain — 6; 0 Participants — p=0.013
Phase 3 N=65 An Implantable Spinal Cord Stimulation Pain Management System
Chronic Pain · Pain, Intractable · Pain
Primary: Change in Visual Analog Scale (VAS) Score From Baseline to 2 Week Post Initial Fitting. — 35 participants with > 50% VAS improvement
N/A N=311 Risk Factors and Mechanisms for Persistent Postsurgical Pain After Total Knee Replacement
Persistent Postsurgical Pain
Primary: Number of Subjects With Post-Operative Persistent Pain (PPP) — 211; 34 Participants
N/A N=5 NSS-Bridge Device for Post-Cesarean Delivery Pain
Acute Pain · Cesarean Delivery
Primary: Opioid Consumption — 31 milligrams of oxycodone
N/A N=63 NSS-2 BRIDGE Device in Post-Operative Pain Management
Acute Pain · Surgery · Abdominal Cancer
Primary: Opioid Consumption — 24; 38; 24; 27 oral morphine mg equivalents (OME)
N/A N=150 Lidocaine and Prevention of Chronic Pain
Surgery
Primary: Number of Participants With Chronic Persistent Pain 3 Months After Surgery as Determined by Character Severity (Yes/no). — 2; 6 participants — p=.19
Phase 4 N=15 Pregabalin and Post-thoracotomy Pain
Chronic Pain
Primary: The Primary Outcome Measure for the Final Study Will be the Incidence of CPTPS at 2 Months.
Phase 4 N=343 PAIN - Postoperative Analgesia INvestigation
Postoperative Pain
Primary: Postoperative Pain as Assessed by a Numeric Pain Scale (NPS) — 5.05; 5.02 units on a scale — p=0.934
N/A N=99 Cryoanalgesia to Prevent Acute and Chronic Pain Following Surgery: A Randomized, Double-Masked, Sham-Controlled Study
Mastectomy · Upper Limb Amputation Below Elbow · Upper Limb Amputation Above Elbow
Primary: Average Pain (Mastectomy Subjects Only) — 0.0; 3.0 score on a scale
N/A N=158 Central Nervous System Amplification in Lumbar Failed Back Surgery Syndrome
Chronic Pain
Primary: Clinical Pain Severity - 50% Reduction Responders vs Nonresponders — -83; 0 percentage of change
N/A N=64 Remote Ischemic PreConditioning Effect on Postsurgical Pain
Pain
Primary: Comparison of Pain Intensity and Unpleasantness Postoperatively — 4.82; 4.83; 4.05; 4.81 units on a scale
N/A N=179 Persistent Postoperative Pain and Joint Stiffness After Total Knee Arthroplasty Performed for Osteoarthritis
Pain · Joint Stiffness
Primary: Presence of Persistent Postoperative Pain Using the Numeric Rating Scale (NRS) — 10 Participants
Phase 2 N=240 Prospective, Randomized Controlled Trial on Perioperative Pregabalin to Reduce Late-onset CRPS After TKA
CRPS
Primary: Epidural Medication Consumption Rate — 6.40; 5.77 mL/h — p=0.003
N/A N=299 Evaluation of Spine Surgery Analgesic Pathway
Posterior Spine Surgery
Primary: Quality of Recovery — 109; 109 units on a scale — p=0.92
N/A N=44 Suicide Prevention for Patients With Chronic Pain
Suicide · Chronic Pain
Primary: Social Problem-solving Inventory - Patient Report — 8.12; 3.64 score on a scale
Phase 3 N=425 Surgical Pain After Inguinal Hernia Repair (SPAIHR)
Pain, Postoperative · Hernia, Inguinal
Primary: Modified Brief Pain Inventory-Short Form (mBPI-sf): Worst Pain 24 Hours Post Surgery — 5.2; 5.4; 4.7; 5.4 scores on scale — p=0.0668
Phase 2 N=24 Oxidative Stress and Surgical Recovery
Surgical Recovery · Pain, Postoperative
Primary: Phosphorylation of STAT-3 in MDSC (Myeloid-derived Suppressor Cells) — 2.162; 2.025 STAT3 archsinh ratio — p=0.5490
N/A N=16 Clinical Analysis of Pain After Hysterectomy
Postoperative Pain
Primary: Type of Chronic Pain After Hysterectomy — 5; 4; 6; 1 participants