N/A N=28 Predictive of Biomarkers of Healing in Chronic Venous Ulceration of the Lower Limb
Varicose Ulcer
Primary: Identification of Biomarkers Predictive of Ulcer Healing. — 9 Number of biomarkers
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=39 Acellular Porcine Dermal Matrix Wound Dressing in the Management of Diabetic Foot Ulcers
Diabetic Foot Ulcers
Primary: Size of Index Wound Based on Calculations Wound Width x Length x Depth 2. Size of Index Wound Based on Calculations Wound Width x Length x Depth — 2.05; 3.33 mm^3
Phase 4 N=21 Wound Management for Sacral Pressure Ulcers With Necrotic Tissue
Pressure Ulcers
Primary: Percentage of Wounds Healed — 63.1; 6.1 percentage of wounds
N/A N=12 Feasibility Study of a Novel Device for Chronic Wounds
Ulcer · Wounds and Injuries
Primary: Ease of Use for Patients — 8; 10; 9 participants
N/A N=132 SNaP Wound Care System Versus Traditional NPWT Device for Treatment of Chronic Wounds
Ulcers · Wounds
Primary: Percent Change in Wound Area — -85.7; -94 percentage of baseline wound area
N/A N=43 Effect of Oasis® Wound Matrix on Stage III and IV Trunk Pressure Wounds Treated With Negative Pressure Wound Therapy
Open Wound Abdominal Wall · Wound Non Healing
Primary: Closure Rate of Non-healing Wounds — 45.79; 89.98 percentage of healing
N/A N=49 The Clinical Efficacy of Next Science Wound Gel (NXTSC) in the Healing of Chronic Wounds
Wound Infection
Primary: The Percentage of Patients Who Had a 50% or Greater Wound Size Volume Reduction After 4 Weeks of Treatment With the Next Science Wound Gel, as Compared to Wounds Treated…
Phase 3 N=68 Efficacy of the Combination of Isosorbide Dinitrate Spray and Chitosan in Diabetic Foot Ulcers
Diabetic Foot Ulcers
Primary: Biopsies — 2.46; 2.64; 2.56; 2.07 UI/dL
N/A N=145 The Effect of Natrox® Oxygen Wound Therapy on the Healing Rate of Chronic Diabetic Foot Ulcers
Diabetic Foot Ulcer · Surgical Wound
Primary: Number of Participants That Achieve Complete Wound Closure During the Twelve Week Study and the Percentage Change in Participant Ulcer Size at 12 Weeks From Baseline…
N/A N=203 AQUACEL® Ag+ Extra™ and Cutimed™ Sorbact® Dressing in the Management of Venous Leg Ulcers Over a 12-week Period
Venous Leg Ulcer · Diabetic Foot
Primary: Effectiveness of AQUACEL® Ag+ Extra™ and Cutimed® Sorbact® on Wound Management — 80; 60 Number of Wounds
N/A N=80 Treatment of Pressure Ulcers Using Biological Skin Substitutes
Pressure Sore
Primary: Percent Change in Wound Area — -78.5; -65.1 percentage change
N/A N=104 Treatment of Full-Thickness Wounds: NPWT Combined With Type-I Collagen Based Advanced Skin Substitute Versus NPWT Alone
Full Thickness Skin Defects · Ulcer
Primary: Percentage Change in Wound Area — 23.73; 15.21; 34.47; 22.52 percentage change
N/A N=40 Clinical Study to Compare 3 Multi-Layered Foam Dressings for the Management of Chronic Wounds
Chronic Wound · Venous Leg Ulcer · Diabetic Foot Ulcer
Primary: % of Participants With Equal or Better Rate of Dressing Durability — 100.0; 94.1; 69.2; 73.3 %participants — p=0.046
Phase 3 N=130 Transdermal Continuous Oxygen Therapy for Diabetic Foot Ulcers
Diabetic Foot Ulcers
Primary: Number of 100% Wound Closure — 55.74; 50.82 percentage of patients
N/A N=8 Evaluation of the Effectiveness of Daily Pulse Lavage Therapy in Chronic Wounds
Chronic Wounds
Primary: Change in Bacterial Counts — 4460; -1030000 cfu/mL
N/A N=41 Developing Strategies for Effective Debridement in Patients for Venous Leg Ulcers
Venous Leg Ulcer
Primary: Change in the Genetic Profile After Debridement in the Intervention Group. — 1031 Number of Differentially Expressed Genes
N/A N=76 Effect of VarIthena on Wound Healing in Venous Leg Ulcers (VLU)
Venous Leg Ulcer
Primary: Change From Baseline in Wound Perimeter — 29.36; 43.64 mm
N/A N=11 Healing Rate of Leg Wounds Treated With Contact and Noncontact Ultrasound: The VIP Ultrasound Protocol
Chronic Ulcer of Lower Extremity
Primary: Total Wound Area — 7.93125; 7.93125; 1.3275; 8.80875 Squared centimiters
N/A N=40 Evaluation Of An Advanced Borderless Dressing
Pressure Ulcer · Leg Ulcer · Diabetic Foot Ulcer
Primary: Change in the Cardiff Wound Impact Schedule-Physical Symptoms of Daily Living (CWIS-PSDL) Scale Score From Baseline to the Week 6 Visit — 54.3; 54.0; 71.2; 56.3 score on…
N/A N=22 Efficacy of Laser Debridement on Pain and Bacterial Load in Chronic Wounds
Wound Open · Chronic Venous Hypertension (Idiopathic) With Ulcer · Diabetic Foot Ulcer
Primary: Pain With Debridement — 3.0; 4.8 units on a scale — p=0.003
N/A N=10 Treatment of Chronic and Non-Chronic Wounds in Patients With Recessive Dystrophic Epidermolysis Bullosa Using Helicoll Collagen Dressings Versus Standard of Care
Epidermolysis Bullosa Dystrophica · Epidermolysis Bullosa
Primary: Percentage of Wound Surface Area Change From Baseline to Week 8 — -63; -8.1 percentage of wound surface area
Phase 4 N=82 Study of Oasis Ultra in Diabetic Foot Ulcers
Diabetic Foot Ulcer
Primary: Percentage of Wounds Closed — 54; 32 percentage of wounds closed
N/A N=40 Trial of Versajet Compared With Conventional Treatment in Acute and Chronic Wounds
Surgical Wound Dehiscence
Primary: Difference in Time to Closure Between Wounds Surgically Excised With VERSAJET™ Hydrosurgery System and Those Surgically Excised Using Conventional Operating Room…
Phase 4 N=40 GrafixPL PRIME Evaluation Case Study
Diabetic Foot Ulcer
Primary: Number of Participants With Complete Closure of the Index Ulcer — 19 Participants
N/A N=150 Negative Pressure Wound Therapy as a Drug Delivery System
Diabetic Foot Ulcers
Primary: Number of Participants Who Achieved Complete Healing or Coverage of the Study Wound — 44; 45 Participants — p=0.87
Phase 4 N=39 Wound Fluid Protease Levels During Use of Novel Wound Dressing
Venous Stasis Ulcers
Primary: Matrix Metalloproteinase Level in Wound Fluid — 0.71; 0.88 mcg/ml
N/A N=30 Procellera and Negative Pressure Therapy for Acute Wounds
Wound
Primary: Wound Infection — 13; 12 participants
N/A N=23 Continuous Diffusion of Oxygen (CDO) Treatment for Healing of Diabetic Foot Ulcers
Foot Ulcer, Diabetic
Primary: Tissue Oxygenation as Measured by Hyperspectral Imaging — 63.58; 61.91; 76.33; 77.55 percent concentration of oxyhemoglobin
N/A N=73 Efficacy, Safety and Economic Benefits of Topical Wound Oxygen Therapy in the Treatment of Chronic Diabetic Foot Ulcers
Diabetic Foot Ulcer
Primary: Wound Closure Within 12 Weeks With the Use of Topical Wound Oxygen Therapy (TWO2) — 15; 5 Participants
Phase 2 N=5 Hidradenitis Suppurativa Wound Care
Hidradenitis Suppurativa (HS)
Primary: Percent Change in Wound Size — 57.2 percentage change in wound size