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Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.

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30 closest matches · ranked by relevance

Phase 2 N=1,009 A Single-Arm, Open-Label, Multicenter Clinical Trial With Nivolumab (BMS-936558) for Subjects With Histologically Confirmed Stage III (Unresectable) or Stage IV Melanoma Progressing Post Prior Treatment Containing an Anti-CTLA4 Monoclonal Antibody (CheckMate 172)

Melanoma
Primary: the Incidence of Highgrade (CTCAE v4.0 Grade 3 or Higher), Treatment Related,Select Adverse Events. — 16; 0; 30; 0 Number of Participants
Bristol-Myers Squibb Results Feb 2020 58.8% serious AE View details

Phase 2 N=25 Denosumab + PD-1 in Subjects With Stage III/ IV Melanoma

Melanoma Stage Iii · Melanoma Stage Iv · Melanoma
Primary: The Antitumor Effect of Denosumab Alone as Represented by the Change in Recent Thymic Emigrant Cells in Peripheral Blood — 2.69; 2.42; 2.55; 1.92 number of cell per…
UNC Lineberger Comprehensive Cancer Center Results Aug 2024 52.0% serious AE View details

Phase 2 N=17 LCCC 1128: Open Label Phase II Trial of the BRAF Inhibitor (Dabrafenib) and the MEK Inhibitor (Trametinib) in Unresectable Stage III and Stage IV BRAF Mutant Melanoma; Correlation of Resistance With the Kinome and Functional Mutations

Stage III Melanoma · Stage IV Melanoma · Unresectable Melanoma
Primary: Change in Kinase Expression — -20.87259; -19.64376; -16.41738; -12.5401 Sum Log 2 Fold Change Kinase Expression
UNC Lineberger Comprehensive Cancer Center Results Sep 2020 64.7% serious AE View details

Phase 1 N=39 Immunotherapy of Stage III/IV Melanoma Patients

Melanoma
Primary: Change From Baseline in Mean Number of Adverse Events (Serious and Non Serious Events) — 13.40; 18.40; 23.80; 19.60 Number of adverse events
Centre Hospitalier Universitaire Vaudois Results Jun 2020 20.5% serious AE View details