N/A N=46 Computerized Cognitive Training in Breast Cancer Survivors
Breast Cancer · Cognitive Change · Cognitive Impairment
Primary: Client Satisfaction Questionnaire — 29.7; 27.9 score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=87 Physical Activity and Neuropsychological Outcomes in a Cancer Population
Cognitive Dysfunction · Breast Cancer Survivors
Primary: National Institutes of Health Toolbox - Cognition Domain- Oral Symbol Digit Test — 7; 3 units on a scale — p=<0.05
N/A N=12 Feasibility of the Memory and Attention Adaptation-Training Geriatrics Intervention in Older Cancer Survivors With Mild Cognitive Impairment
Cognitive Dysfunction
Primary: MAAT-G Feasibility Completion Rate — 10 Participants
N/A N=132 Online Treatment of Cognitive Impairment and Insomnia in Cancer Survivors
Cancer · Insomnia · Cognitive Impairment
Primary: The Functional Assessment of Cancer Therapy - Cognitive Function (FACT-Cog) Version 3 — 39.39; 38.79; 48.28; 44.71 score on a scale
N/A N=45 Metacognitive Strategy Training in Cancer-related Cognitive Impairment
Breast Cancer Female
Primary: Telehealth Usability Questionnaire (TUQ) — 6.38; 6.31 units on a scale
N/A N=47 The "Light for the Brain" Study
Hematopoietic Stem Cell Transplantation · Cognitive Impairments · Sleep
Primary: Cognitive Functioning (Neuropsychological Tests) — 0.24; 0.16; 0.43; 0.50 z-score
Phase 4 N=469 Learning Impairments Among Survivors of Childhood Cancer
Acute Lymphoblastic Leukemia · Brain Tumors
Primary: Brain White Matter Volume for Patients Versus Sibling Controls — 27; 30.3 percentage — p=<.0001
N/A N=72 Memory and Attention Adaptation Training-Geriatrics (MAAT-G) Phase II
Cancer-related Problem/Condition · Cognitive Impairment
Primary: Mean of the Functional Assessment of Cancer Therapy-Cognition (FACT-COG) — 155.8; 152.7 score on a scale
Phase 2 N=51 Memantine for Prevention of Cognitive Decline in Patients With Breast Cancer
Cognitive Decline · Chemo-brain
Primary: Change in Visual Working Memory - Delayed Matching to Sample Test — 16; 13; 16 Participants
N/A N=153 Exercise Program in Cancer and Cognition
Breast Cancer
Primary: Change in Cognitive Function — -0.05; 0.01; 0.21; 0.17 z-score
N/A N=40 Cognitive Behavioral Therapy (CBT)-Insomnia for Lung Cancer
Chronic Insomnia
Primary: Sleep Efficiency — 79.70; 85.21 percentage of sleep efficiency
N/A N=5 Memory and Attention Adaptation Training-Geriatrics (MAAT-G)
Cancer-related Problem/Condition · Cognitive Impairment
Primary: System Usability Scale (SUS) — 90.6 score on a scale
Phase 2 N=96 Cognitive Behavioral Therapy +/- Armodafinil for Insomnia and Fatigue Following Chemotherapy
Insomnia · Fatigue · Breast Cancer
Primary: Change in Insomnia Severity Index From Baseline to Post-intervention — -4.93; -6.36; 1.04; -1.43 units on a scale
Phase 2 N=97 The Effects of Physical Activity and Low-Dose Ibuprofen on Cognitive Function in Cancer Patients
Cancer-related Cognitive Difficulties
Primary: Memory Performance as Assessed by Computerized Cognitive Assessment - Mean Values by Arm — 75.2; 82.7; 83.6; 74.3 % correct — p=0.9168
N/A N=45 Computer Training Program for Younger Patients With a Brain Tumor Who Underwent Radiation Therapy
Brain Neoplasm · Recurrent Brain Neoplasm
Primary: Intervention Compliance — 0.39; 0.50 Proportion of Participants
N/A N=45 Electrophysiological Biomarkers of Chemotherapy-related Cognitive Impairment and Recovery
Myelodysplastic Syndrome · Effects of Chemotherapy · Mild Cognitive Impairment
Primary: Change From Baseline Capture Task Performance at 1- and 3- Months — .103; -.039; .066; .067 change in proportional response time
Phase 2 N=62 Study of Donepezil in Female Breast Cancer Survivors With Cognitive Dysfunction
Anxiety Disorder · Breast Cancer · Cognition Disorders
Primary: Retention — 71.0; 80.7 percentage of participants
N/A N=110 Cognition and Psychotherapy in PTSD
Posttraumatic Stress Disorder (PTSD)
Primary: Change in PTSD Checklist (PCL-5) — 9.25; 11.94; 15.91 change in units on a scale
Phase 2 N=22 Nicotinic Treatment of Post-Chemotherapy Subjective Cognitive Impairment: A Pilot Study
Chemo Brain · Chemotherapy-related Cognitive Impairment · Chemo Fog
Primary: Change in the Functional Assessment of Cancer Therapy-Cognitive Function (FACT-Cog) PCI Scale — 7.00; 11.55; 16.80; 16.64 units on a scale — p==0.41
Phase 2 N=87 Low-Dose Ibuprofen in Improving Cognitive Impairment in Patients With Cancer
Cognitive Impairment · Malignant Neoplasm
Primary: Effects of Ibuprofen on Alleviating Chemotherapy-related Cognitive Impairment — 89.98; 91.08; 105.54; 107.75 score on a scale — p=0.7917
N/A N=139 Brief Behavioral Intervention for Insomnia During Chemotherapy
Breast Cancer · Insomnia
Primary: Insomnia Severity Index (ISI) — 13.73; 14.93; 11.28; 10.16 score on a scale
N/A N=392 Intervention Study of Depression in Breast Cancer Patients
Breast Cancer · Depression · Anxiety
Primary: Hamilton Depression Rating Scale (HAMD-17) — 11.52; 13.31; 11.01; 10.23 units on a scale
N/A N=33 Treatment for Executive Dysfunction in Adult Survivors of Childhood Acute Lymphoblastic Leukemia
Acute Lymphoblastic Leukemia
Primary: Feasibility of At Home tDCS Intervention — 25 Participants
N/A N=50 Problem Solving Skills Training in Adult Cancer Survivors: Bright IDEAS-AC
Colo-rectal Cancer
Primary: Mean Physical Health of Patient at Enrollment — 77.2; 82.7 score on a scale
N/A N=14 Managing Cancer and Living Meaningfully
Mood · Cancer Brain
Primary: Recruitment for CALM — 14; 14; 12 Participants
N/A N=57 Mindfulness and CBT for Sleep
Hematologic Malignancy
Primary: Feasibility as Measured by Number of Participants Accrued to Single-arm Pilot — 32 Participants
N/A N=321 Trial of Individual Psychosocial Interventions for Cancer Patients
Advanced Solid Tumor Diseases
Primary: Participant Meaning Making Scores Using the Life Attitude Profile-Revised (LAP-R) — 37.07; 38.28; 36.80; 42.22 scores on a scale
Phase 4 N=60 Characterizing and Predicting Drug Effects on Cognition
Cognitive Deficits
Primary: Change From Baseline in COWA Unique Word Count — -0.407725385; -0.425898667; -0.412534118; -0.108298333 Word Count
Phase 3 N=226 EGb761 in Maintaining Mental Clarity in Women Receiving Chemotherapy for Newly Diagnosed Breast Cancer
Breast Cancer · Neurotoxicity
Primary: The Level of Cognitive Dysfunction as Measured by the High Sensitivity Cognitive Screen (HSCS) Overall Score. — 12.2; 12.6; 3.9; 2.6 units on a scale*months — p=0.84
N/A N=200 Validation of the Freund Clock Drawing Test to Screen for Cognitive Dysfunction in Cancer Patients
Elderly Cancer Patients · Cognitive Impairment
Primary: Validation of the Freund Clock Drawing Test, and Its Predefined Cut-off of ≤ 4, as a Screening Tool to Identify Elderly Cancer Patients in Need of a More In-depth…