Phase 2 N=114 Colon Staining Efficacy of Single Oral Doses of Methylene Blue MMX
Colon Staining in Preparation for Colonoscopy
Primary: Evaluation of Mucosal Staining Efficacy — 6.8; 2.3; 8.1; 7.0 scores on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=2,000 Improving Bowel Preparation for Colonoscopy With a Simple Educational Card
Colonic Polyps · Colonic Neoplasms
Primary: Boston Bowel Preparation Scale Score — 6; 6 units on a scale
Phase 3 N=136 Efficacy of Morning-only Bowel Preparation for Afternoon Colonoscopy.
Colon Cancer
Primary: Comparing All Morning Bowel Prep to Evening Bowel Prep for Patients Undergoing Afternoon Colonoscopies. (Using Ottawa Scale Scores, Range 0-14) Lower Score Indicates a…
Phase 2 N=147 Yoga and Bolus Lukewarm Saline as Rapid Colonoscopy Preparation
Colonic Neoplasms
Primary: Efficacy of Large Bowel Cleansing as Assessed by the Physician Performing the Colonoscopy — 18.69; 20.1 Score
N/A N=191 Split Dose Golytely With Amitiza Pretreatment Versus Split Dose Golytely Plus Placebo in Outpatient Colonoscopy
Bowel Preparation for Colonoscopy
Primary: The Overall Cleanliness of the Prep as Measured by the Ottawa Scale — 4.8; 6.2 Ottawa Score
Phase 4 N=158 Amitiza® Plus GoLYTELY® (PEG) Versus Placebo Plus GoLYTELY® for Outpatient Colonoscopy Preparation
Colonoscopy
Primary: Endoscopist Evaluation of Colon Cleanliness in the Lubiprostone Group vs the Placebo Group — 1.38; 1.24 score on a scale — p=0.05
N/A N=122 Optimization of the Bowel Preparation Regimen for the PillCam® COLON 2 Capsule Endoscopy Procedure
Colorectal Cancer Screening
Primary: Bowel Cleansing Level of Two Different Bowel Preparation Methods for PillCam® Colon Capsule Endoscopy (CCE) — 6.8; 16.7; 14.0; 14.6 percentage of particpants
Phase 3 N=300 Investigation of PICOPREP and PEG-ELS for Bowel Preparation for Colonoscopy
Colonoscopy
Primary: The Ottawa Scale Score of Patients Who Had Successfully Completed the Colonoscopy Examination After Having Completed the Study Bowel Preparation — 4.73; 4.91 units on a…
Phase 4 N=360 Efficacy and Safety of Standard Oral Colonoscopic Preparations With or Without Neostigmine Compared to Pulse-Irrigation Colonic Lavage
Spinal Cord Injury
Primary: Quality of Bowel Preparation — 3.4; 2.5; 3.6; 7.4 units on a scale
Phase 4 N=308 F38-27: An Evaluation of 2 Different Bowel Cleansing Preparations in Adult Subjects
Colonoscopy
Primary: Efficacy: Percentage of Patients With Successful Preparations Based on a 4 Point Scale — 77.6; 80.1 percent of participants — p=0.005
Phase 2 N=40 2 Regimens of Lactulose for Colonoscopy Preparation in Adults
Colonoscopy Preparation
Primary: Efficacy of Lactulose as a Preparation for Colonoscopy. — 8.2; 7.2; 7.5; 8.4 units on a scale
Phase 4 N=425 A Trial Comparing Split-Dose Miralax With Amitiza Pretreatment Versus Dulcolax Pretreatment Versus Golytely for Bowel Cleansing Prior to Colonoscopy
Colonoscopy
Primary: The Cleanliness of the Prep as Measured by the Ottawa Scale — 6.3; 6.8; 6.9; 5.1 Ottawa Scale
N/A N=4 Indocyanine Green Fluorescent Molecular Imaging of the Gastrointestinal Tract
High Risk Polyposis Syndrome · Distal Colonic Lesions · Colorectal Polyps
Primary: Number of Neoplastic Lesions Detected — 3 Lesions
Phase 4 N=600 Gatorade/Miralax With or Without Bisacodyl Versus NuLytely for Colonoscopy Preparation
Preparation for Colonoscopy
Primary: The Quality of the Colon Preparation Will be Graded Using the Boston Bowel Preparation Scale — 7.86; 8.05; 7.99 units on a scale
Phase 3 N=603 Investigation of PicoPrep Versus HalfLytely for Bowel Preparation for Colonoscopy - Day Before PicoPrep
Bowel Preparation
Primary: Percentage of Participants Classified as Successes (Excellent and Good Ratings) According to the Aronchick Scale As Assessed by a Blinded Gastroenterologist — 83.0; 79.7…
Phase 3 N=500 Study 302: BLI4900 Versus an FDA-approved Comparator in Adult Subjects Prior to Colonoscopy
Colonoscopy
Primary: Proportion of Subjects With Successful Bowel Preparation — 212; 211 Participants — p=<0.001
Phase 2 N=32 Efficacy and Safety of Bisacodyl and Lactulose as a Preparation for Colonoscopy
Colonoscopy Preparation
Primary: Efficacy of Bisacodyl and Lactulose as a Preparation for Colonoscopy. — 5.7; 7.4; 7.8 units on a scale
Phase 3 N=637 A Phase III Study With FE 999169 Versus Niflec for Colon Cleansing
Colon Cleansing in Preparation for Colonoscopy
Primary: The Efficacy Rate Based on the Overall Colon Cleansing Effect as Assessed by the Independent Central Judging Committee Using the Japanese Colon Cleansing Scale — 97.7…
Phase 4 N=268 Effect of Simethicone on Screening Colonoscopy
Adenoma Colon
Primary: Adenoma Detection Rate — 43; 54 adenomas
Phase 4 N=136 Miralax (PEG 3350) vs. Golytely as Bowel Preparation for Screening Colonoscopy
Colon Cancer
Primary: Boston Prep Scale — 7.0; 7.2 units on a scale — p=.45
Phase 3 N=917 A Study Comparing the Sodium Picosulfate, Magnesium Oxide and Anhydrous Citric Acid Oral Solution With PREPOPIK® for Colon Cleansing in Preparation for Colonoscopy
Bowel Preparation
Primary: Percentage of Subjects Classified as a Responder Defined by "Excellent" or "Good" — 87.7; 81.5 Percentage of participants — p=0.0067
Phase 4 N=1,044 Polyethylene Glycol Versus Low Volume Solutions Prior to Colonoscopy
Colonoscopy
Primary: Quality of Bowel Preparation Using the Aronchick Scale ( Score 1+2) — 110; 145; 100; 134 Participants
Phase 4 N=2,239 Comparative Effectiveness of Split-Dose Colonoscopy Bowel Preparation Regimens
Colorectal Cancer
Primary: Colonoscopy Completion Rate — 591; 600 Participants
Phase 3 N=519 Study 301: BLI4900 Versus an FDA-approved Comparator in Adult Subjects Prior to Colonoscopy
Colonoscopy
Primary: Proportion of Subjects With Successful Bowel Preparation — 215; 212 Participants — p=<0.001
Phase 3 N=91 A Safety and Efficacy Study of a Bowel Cleansing Preparation (BLI800) in Pediatric Subjects Undergoing Colonoscopy
Colonoscopy
Primary: Number and Percentage of Subjects With Successful Bowel Cleansing — 25; 22; 19 Participants — p=0.003
Phase 3 N=608 Investigation of PicoPrep Versus HalfLytely for Bowel Preparation for Colonoscopy - Split Dose PicoPrep
Bowel Preparation
Primary: Percentage of Participants Classified as Successes (Excellent and Good Ratings) According to the Aronchick Scale As Assessed by a Blinded Gastroenterologist — 84.2; 74.4…
N/A N=229 Clinical Evaluation of Water Immersion Colonoscopy Insertion Technique
Colonoscopy · Digestive System · Endoscopy
Primary: Colonoscopy Success With Minimal Sedation — 57; 32 Participants
Phase 4 N=260 Improving Bowel Cleansing With a Smart Phone Application
Cathartics · Mobile Applications
Primary: Bowel Preparation Was Evaluated Using the Harefield Cleansing Scale (HCS). The Scale Was the Primary Outcome Measure — 17.05; 16.52 units on a scale
Phase 3 N=552 A Safety and Efficacy Comparison of BLI4700 Bowel Prep Versus an FDA-approved Comparator in Adults Prior to Colonoscopy
Colonoscopy
Primary: Number and Percentage of Subjects With Successful Bowel Cleansing — 257; 241 Participants — p=<0.001
N/A N=180 Efficacy and Acceptability of Low-Residue Diet Package (Enimaclin®) as Diet Control Before Colonoscopy
Dietary Modification
Primary: Overall Cleansing Level at Colonoscopy by Ottawa Bowel Preparation Scale — 2.58; 3.22; 2.97 units on a scale — p=0.435