30 closest matches · ranked by relevance
Comparison of Octaplas LG and Octaplas SD
Primary: Recovery of the Coagulation Factors I, II, V, VII, VIII, IX, X, and XI — 8.11; 9.12; 7.08; 6.68 Percentage change
Liver Surgery · Liver Dysfunction · Coagulopathy
Primary: Number of Participants With Adverse Drug Reactions (e.g., Allergic Reactions, TEs, TEEs (Thromboembolic Events) and Hyperfibrinolytic Events) — 5; 0; 0; 0 participants
Adverse Effects in the Therapeutic Use of Plasma Substitutes
Primary: Monitoring of Adverse Drug Reactions Caused by the Octaplas™Used for Plasma Exchange. — 0; 5; 3; 8 event
Reversal of Anticoagulant Treatment
Primary: INR Response — 74; 31 Participants
Significant Bleeding Risk
Primary: Hemostatic Efficacy Rating by IEAB — 41; 50; 58; 47 Participants
Congenital Fibrinogen Deficiency · Afibrinogenemia
Primary: Ratio of Octafibrin/FIBRYGA® to Haemocomplettan® P/RiaSTAP(TM) for Fibrinogen Activity Normalized Area Under the Curve Unstandardized — 1.196 ratio
Healthy Volunteers
Primary: Number of Participants With Platelet Units Containing an Acceptable Residual WBC Level — 92; 93; 93; 1 Participants
Freeze Dried Plasma in Healthy Volunteers
Primary: Safety of Single Infusions of FDP at Increasing Fixed Doses in Normal Healthy Subjects by Evaluating Vital Signs and Laboratory Tests — 4; 4; 4; 4 Participants
Immune Thrombocytopenic Purpura
Primary: Percentage of Participants With a Clinical Response — 80.0 Percentage of participants
Healthy Volunteers
Primary: Number of Participants With Platelet Units Containing an Acceptable Residual WBC Level — 93; 93; 93; 0 Participants
Chronic Kidney Disease
Primary: Comparison of Urea Removal Under Conditions of Routine Hemodialysis. — 1.64; 1.61; 1.42; 1.40 ratio
Bleeding Disorder · Hypofibrinogenemia; Acquired
Primary: Intra-operative Blood Loss — 1380.7; 1660.13 mL — p=<0.001
Hematologic Diseases · Secondary Immune Deficiency
Primary: Infusion Time of Multigam IV 5% and Multigam IV 10% — 4.92; 2.29 hour — p=<0.0001
Granulocyte/ Polymorphonuclear Cells
Primary: Granulocyte/PMN Cell Collection Efficiency — 54.7; 52.4; 41.9; 44.7 percent cells processed
Chronic Kidney Failure
Primary: Ease of Use: Priming Blood Side — 139; 13; 13; 80 Number of Dialyzers
Bleeding Cardiac Surgery Patients
Primary: Number of Patients Requiring Additional Hemostatic Intervention — 166; 125; 47; 82 Participants — p=<0.0001
Hypofibrinogenemia · Bleeding
Primary: Total Number of RBCs Used Over Admission — 5.8; 6.7 RBC Units
Acute Coagulopathy
Primary: 28 Day In-hospital Mortality — 20; 11 participants — p=0.04
Primary and Secondary Immunodeficiency and Other Conditions Requiring Regular Administration of Octagam 5% or 10% IVIG
Primary: Adverse Drug Reactions — 17; 37; 0; 1 Participants
Pediatric HD · Bleeding
Primary: A Composite of the Number of Any Allogeneic Blood Products (RBCs, Plasma, Platelets, Cryoprecipitate) Transfused From Administration of the Study Medication Until 48…
Operation Site Bleed
Primary: The Primary Objective of This Investigation is to Gather Information to Support the Effectiveness of Thrombi-Gel as Compared to a Gelatin Sponge (Gelfoam) Plus Thrombin…
Cataracts
Primary: Percent Loss of Endothelial Cells — 9.48; 15.66; 23.69; 25.70 Percent Loss
Cardiac Surgery · Cardiopulmonary Bypass
Primary: Calculated Blood Loss at 3rd Post Operative Day (POD) — 19.9; 15.9 ml/kg
Healthy
Primary: Arthrex Angel System for PRP Concentration — 61.73; 60.86 CD45+ cells/uL
Hemophilia A
Primary: Area Under the Plasma Concentration Versus Time Curve (AUC) From 0 to 48 Hours. One-Stage Activated Partial Thromboplastin Time (aPTT) -Based Assay Performed at Central…
Volume Deficiency of the Midface
Primary: Assess and Compare Tissue Aggregation and Visualization of Hyaluronic Acid Fillers by Investigator Using Ultrasound — 10; 1; 7; 9 Participants
Complications of Corneal Transplant
Primary: Endothelial Cell Loss Post EK for Donor Corneas Preserved in Life 4°C and Optisol GS Corneal Storage Media — 20; 18 % endothelial cell loss — p=< 0.05
Bleeding · Blood Loss, Surgical · Cardiovascular Surgical Procedures
Primary: Chest Tube Output — 1022; 937 mL — p=0.84
Apheresis Related Hypotension
Primary: Rate of Significant Hypotensive Adverse Events — .035; .051 % of significant hypotensive AEs
Cirrhosis · Coagulopathy
Primary: Intra-operative Blood Loss — 2000; 3000 milliliters