30 closest matches · ranked by relevance
Glaucoma · Endothelial Cell Loss, Corneal
Primary: Endothelial Cell Count Change — 2; -1; 0; -4 % change compared to baseline
Corneal Endothelial Decompensation · Fuchs' Endothelial Dystrophy
Primary: Graft Failure — 32; 15 eyes
Myopia
Primary: Central Endothelial Cell Density (All Eyes) — 2654.0; 2639.0; 2633.0; 2551.0 cells/mm^2
Cornea Preservation Time · Endothelial Keratoplasty · Transplant Success
Primary: Number of Eyes With Corneal Graft Failure Within 3 Years of Surgery — 30; 49 Eyes — p=0.02
Corneal Edema Secondary to Corneal Endothelial Dystrophy
Primary: Best Spectacle Corrected Visual Acuity (BSCVA) — 1; 3; 7; 9 Participants
Age-Related Macular Degeneration · Retinal Vein Occlusion · Diabetic Macular Edema
Primary: Change From Baseline in Mean Endothelial Cell Density — -35.86 cells/millimeter squared
Fuchs Endothelial Dystrophy · Corneal Edema
Primary: Endothelial Cell Loss — 28; 36 percentage of endothelial cell loss — p=0.10
Corneal Endothelial Cell Loss · Ocular Pain · Ocular Inflammation
Primary: Change From Baseline in Central Corneal Endothelial Cell Counts — -243.4; -184.8; -260.3 cells/mm^2 — p=0.4529
Fuchs' Dystrophy · Corneal Edema
Primary: Intraocular Pressure — 11; 27 eyes
Ametropia
Primary: Endothelial Bleb Areas on Cornea: Session A- Open Eye — 0.1; 2.0; 0.2; 2.1 Percent Difference of Bleb Area
Fuchs' Endothelial Corneal Dystrophy
Primary: Central Corneal Endothelial Cell Density (ECD) at Week 12 — 530.86; 468.02; 228.05 cells/mm2 — p=0.0065
Persistent Corneal Epithelial Defect
Primary: Percentage of Patients Achieving Corneal Healing (<0.5 mm2 Lesion Size) of the Persistent Corneal Epithelial Defect at 4 Weeks — 5 Participants
Corneal Edema · Corneal Endothelial Dysfunction
Primary: Percentage of Participants Achieving ≥15-letter Improvement in Best-corrected Visual Acuity (BCVA) at Month 6 - Imputed Data — 14.3; 44.4; 10.5; 36.8 Percentage of…
Fuchs Endothelial Dystrophy
Primary: Change in Central Corneal Thickness — -23; -2 microns
Complications of Corneal Transplant
Primary: Endothelial Cell Loss Post EK for Donor Corneas Preserved in Life 4°C and Optisol GS Corneal Storage Media — 20; 18 % endothelial cell loss — p=< 0.05
Fuchs' Corneal Endothelial Dystrophy (FCED)
Primary: Incidence and Severity of Ocular TEAEs. — 3; 6; 1; 1 Participants
Corneal Endothelial Dystrophy · Corneal Edema
Primary: Immunologic Rejection — 0 Participants
Corneal Disease · Fuch's Dystrophy · Pseudophakic Corneal Edema
Primary: Graft Failure — 142; 82 participants
Corneal Epithelial Defect · Diabetic Retinopathy · Penetrating Keratoplasty
Primary: Patients With Corneal Epithelial Healing Time Within 14 Days — 78; 73 participants
Cataract
Primary: Cumulative Dissipated Energy (CDE) — 0.213; 1.718 unitless — p=<0.0001
Refractive Error · Dry Eye
Primary: Mean Number of Viable Epithelial Cells Collected Directly From the Ocular Surface After 2 Hours and 4 Hours of Wear, Phase 1 — 15; 20; 18; 22 cells
Corneal Ulcer · Leukoma
Primary: Incidence of Treatment-Emergent Adverse Events — 0 events
Primary Open Angle Glaucoma · Cataract
Primary: Percentage of Eyes With Sight-threatening Adverse Events (AEs) — 18.5; 0.0; 0.0; 0.0 percentage of eyes
Corneal Neovascularization · Corneal Graft Failure
Primary: Number of Participants With Graft Failure at Week 39 and 52 — 0; 1; 1; 1 Participants
Progressive Keratoconus
Primary: Difference Between Treatment Groups in the Change From Baseline to Month 6 in Kmax — -0.3; 0.6 Diopters — p=0.0004
Keratolysis
Primary: Time From Surgery to Device Loss or Replacement — 95; 34 median weeks from surgery to removal
White Blood Cells
Primary: Leukocyte Population — 583187; 420345; 738140 Leukocytes
Limbal Stem Cell Deficiency
Primary: Primary Safety Events of Interest — 1; 0; 0; 0 Participants
Corneal Neovascularization
Primary: Heart Rate — 68.7 Beats per Minutes
Normal Contact Lens Wear
Primary: HRT Corneal Scan — 85; 66; 49; 63 cells/mm^3