N/A N=10 An Open Single-centre Investigation Evaluating Efficacy in Second Degree Partial Thickness Burns Using a Silicone Contact Layer Containing Silver.
Wound Healing
Primary: Number of Participants With Wound Healing — 10 participants
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Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 1 N=30 StrataGraft® Skin Tissue as an Alternative to Autografting Deep Partial-Thickness Burns
Skin Wound · Burns · Trauma-related Wound
Primary: Number of Participants With Wound Closure of the Treatment Sites at Three Months — 29; 29 Participants
Phase 3 N=71 StrataGraft® Skin Tissue in the Promotion of Autologous Skin Regeneration of Complex Skin Defects Due to Thermal Burns That Contain Intact Dermal Elements
Burn, Thermal
Primary: Percent Area of Treatment Sites Requiring Autografting by Month 3 — 4.33; 102.10 percentage of treatment sites — p=<0.0001
N/A N=45 A Clinical Investigation to Evaluate Efficacy of Mepitel Ag in Partial Thickness Second Degree Burns
Burns · Wound Healing
Primary: Number of Subjects Healed at Day 14. — 35 participants
Phase 4 N=20 Comparison of Wound Bed Establishment in Facial Burns
Burns
Primary: Time to Wound Epithelialization — 37.4; 37.6 days — p=.0853
N/A N=8 An Investigation to Evaluate a New Donor Site Dressing in Surgical Burn Patients
Donor Site Complication
Primary: Percentage of Participants Who Had > 95 % Epithelialization at Day 10 — 0 percentage of participants
N/A N=14 Assessment of Safety and Effectiveness of Biodegradable Temporizing Matrix in the Treatment of Deep Burn Skin Injuries
Burns
Primary: BTM 'Take' Rate — 95.22 percentage of BTM take per subject
N/A N=30 ReCell® Combined With Meshed Skin Graft in the Treatment of Acute Burn Injuries
Burns
Primary: Number of Participants With Confirmed Treatment Area Closure of RECELL-treated Wounds Compared to Control (Non-inferiority) — 24; 22; 2; 4 Participants
N/A N=101 A Multicenter Comparative Study of the ReCell Device and Autologous Split-thickness Meshed Skin Graft in the Treatment of Acute Burn Injuries
Burns
Primary: Incidence of RECELL-treated Area Closure Compared to Control at 4 Weeks (Non-inferiority) — 82; 87; 82; 83 Participants
Phase 3 N=34 Effect of EGF With Silver Sulfadiazine Cream Compared With Silver Zinc Sulfadiazine Cream for Treatment of Burn Wound
Deep Partial Thickness Burn
Primary: Time of Healing by Monitoring Duration (Days) at the Beginning of Treatment and the Day of Completely Epithelialization (Complete Epithelialization Means no Open Wound…
N/A N=18 Fractional Ablative Laser Treatment for Skin Grafts
Burn Scar · Skin Graft Scar
Primary: Contracture of Scar Surface Area (Percentage of Original Area) — 97; 97 percentage
N/A N=32 Split Thickness Donor Site Healing With MIST Study
Burns · Trauma · Venous Ulcers
Primary: Rate of Wound Healing — 12.1; 21.3 Days
N/A N=15 Evaluation of Antimicrobial Soft Silicone, Silver Containing, Foam Dressing, Mepilex Border Ag, in Second Degree Burns
Burns
Primary: Evaluate the Experience of Using Mepilex Border Ag ( a Silver Dressing) in Normal Clinical Practice — 9 burns healed
Phase 3 N=1 StrataGraft Safety, Tolerability and Efficacy in Pediatric Subjects
Skin Wound · Burns · Trauma-related Wound
Primary: Percentage of Participants Who Achieved Confirmed Complete Closure of StrataGraft Treatment Sites Without Autograft Within 12 Weeks of StrataGraft Application — 100…
N/A N=34 Study of Cellutome System for Treatment of Individual Lesions in EB Pts
Epidermolysis Bullosa
Primary: Percentage of Grafts Successfully Treated — 78 Percentage of grafts
Phase 4 N=74 Liposomal Bupivacaine Versus Lidocaine for Skin Graft Donor Site Pain
Pain, Postoperative · Burns
Primary: A Measurement of Post Operative Pain Involving Skin Graft Donor Site Using Visual Analog Scale (VAS) Ranging 0-10, at 8 Hours Post-operatively — 3.14; 3.68; 3.67 score…
N/A N=65 Exercise in Burn Survivors: Cooling Modalities
Burn Injury
Primary: Change in Core Temperature (°C) During Control Intervention — .578; .920; .622; .885 °C
N/A N=29 Fractionated Carbon Dioxide Laser and Burn Scar Contractures: Evaluation of Post-Treatment Scar Function and Appearance
Burn Scars
Primary: Scar Pigmentation, Baseline vs 15-months — 50.93; 49.59 units on a scale
N/A N=39 Acellular Porcine Dermal Matrix Wound Dressing in the Management of Diabetic Foot Ulcers
Diabetic Foot Ulcers
Primary: Size of Index Wound Based on Calculations Wound Width x Length x Depth 2. Size of Index Wound Based on Calculations Wound Width x Length x Depth — 2.05; 3.33 mm^3
Phase 4 N=34 Lidocaine For Treatment of Post-operative Pain From Donor Sites Following Burn Injury.
Pain
Primary: Pain Change — -3.8; -4.0 units on a scale — p=<0.05
Phase 4 N=36 Continuous Lidocaine Infusion for Management of Perioperative Burn Pain
Thermal Burns
Primary: Narcotic Consumption (Measured in mg/kg Narcotic Consumption) — 57.5; 67.75 mg/kg narcotic consumption
Phase 4 N=43 Open, Prosp, Rand. Invest. Evaluating Pain With Mepitel One vs.Bridal Veil and Staples on Split Thickness Skin Grafts
Deep Partial Thickness Burn · Full Thickness Burns
Primary: VAS Score for Pain Before Dressing Removal — 11.0; 4.0 units on a scale
N/A N=76 Continued Access to the Recell® Device for Treatment of Acute Burn Injuries
Burns
Primary: Percentage of Participants With Wound Healing — 95.3 percentage of participants
N/A N=52 Investigation of the Clinical Performance of Biatain Fiber Ag on Burns
Partial-thickness Burn
Primary: Percentage of Wounds Healed Within 14 Days — 83.7; 74.8; 70.6 percentage of wounds healed
N/A N=104 Treatment of Full-Thickness Wounds: NPWT Combined With Type-I Collagen Based Advanced Skin Substitute Versus NPWT Alone
Full Thickness Skin Defects · Ulcer
Primary: Percentage Change in Wound Area — 23.73; 15.21; 34.47; 22.52 percentage change
N/A N=12 CONTINUED ACCESS PROTOCOL: Demonstration of the Safety and Effectiveness of ReCell® Combined With Meshed Skin Graft for Reduction of Donor Area in the Treatment of Acute Burn Injuries
Burns
Primary: Number of Participants With Confirmed Treatment Area Closure of RECELL-treated Wounds Compared to Control (Non-inferiority) — 9; 9 Participants
N/A N=3 Indocyanine Green (ICG) and SPY Imaging for Assessment of Burn Healing
Burns
Primary: Perfusion of Burned Area — 200; 100; 205; 180 % perfusion compared to normal skin
N/A N=54 Effectiveness of Pressure Garment Therapy After Burns
Hypertrophic Scarring After Burn Injury
Primary: Pressure Under Compression Garment — 25; 6.4 mm Hg
N/A N=96 Comparison of Mepitel Ag vs Antibiotic Ointment Used With Soft Cast Technique for Treatment of Pediatric Burns
Burns
Primary: Change in Wound Appearance From Initial Injury Until Wound Healed — 43; 51 Burns
Phase 4 N=48 Santyl vs. Sharp Debridement of Diabetic Foot Wounds
Diabetic Foot Ulcers · Foot Wounds
Primary: Bates-Jensen Wound Assessment Score - Modified (BWAT-m) — 15.8; 13.8 units on a scale — p==0.208