N/A N=20 Dental Appliance for Parkinson's Disease
Parkinson Disease
Primary: Changes in Gait Velocity — 1.10; 1.15 m/s
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=170 Evaluating the Effect of Tooth Cleaning Devices on Oral Health
Dental Plaque
Primary: Residual Protein Concentration — 33.5; 28; 20.4; 20.2 ug/mL
N/A N=42 Efficacy of Plaque Removal of a Novel Brushing Device
Dental Plaque
Primary: Change From Baseline in Dental Plaque Removal Efficacy Using Turesky Modification of the Quigley-Hein Plaque Index — 0.29; 0.6 units on a scale
Phase 4 N=49 A Clinical Study to Evaluate the Efficacy of a Range of Dental/Denture Products for Improved Oral Health in Partial Denture Wearers
Gingivitis
Primary: Mean Bleeding Index (BI) at Week 12 — 0.45; 0.76 Score on a scale — p=<0.0001
N/A N=140 A Study to Determine the Effects of Adding an Experimental Device With Mouthrinse to Oral Care Regimen
Gingivitis
Primary: Interproximal Mean Plaque Index at Week 4 — 2.674; 2.213; 2.005 Units on a scale — p=<0.001
N/A N=348 Dental Support Device in the Second Stage of Labor
Labor
Primary: Dilation Duration of Second Stage of Labor Time — 82; 90 minutes
N/A N=53 Use of Two Dissolvable Therapeutics Under Removable Partial Dentures
Edentulous Jaw · Edentulous Mouth
Primary: Change From Baseline in Patient Comfort for as Assessed by Numerical Scale. — 0.99; 1.16 units on a scale
Phase 3 N=105 Clinical Study to Examine Brushing on Dental Implants
Gingival Diseases
Primary: Mombelli Plaque Index (mPI) for Natural Teeth — 1.96; 1.82 units on a scale — p=0.05
N/A N=100 Reducing Care-Resistant Behaviors During Oral Hygiene in Persons With Dementia
Care-resistant Behavior · Dementia
Primary: Care-Resistant Behavior — 4.84; 6.3; 4.42; 4.91 units on a scale — p=0.1433
N/A N=414 Oral Hygiene in Assisted Living
Aging · Long-Term Care
Primary: Plaque Index Score for Long-Term Care (PI-LTC) - Baseline-Aim2 — 1.6; 1.6 score on a scale — p=0.77
N/A N=50 Curved Soft-Picks on Plaque Accumulation on Patients With Gingivitis
Gingivitis
Primary: Change in Interproximal Plaque by Modification of the Quigley-Hein Plaque Index at 14 Days — 0.03; -0.07 score on a scale
N/A N=58 In Home Assessment of Three Anti-Snoring Devices, a Cross Over Study
Snoring
Primary: Bed Partners' Rating of Sleep Disturbance Due to Partner Snoring — 5.0; 3.8; 4.4 units on a scale — p=<.001
Phase 2 N=39 Dental Plaque Removal Ability of Prototype Power Toothbrush Versus a Manual Toothbrush in Healthy Participants
Dental Plaque
Primary: Change in Whole Mouth Rustogi Modified Navy Plaque Index (RMNPI) Score From Pre-Brushing to Post-Brushing (When Prototype Power Toothbrush [PTB] Was Used in 'Gumline'…
N/A N=19 Frequency of Denture Cleanser Use and Denture Cleanliness
Denture Cleansers
Primary: Change From Baseline in Aerobic Bacteria Microbial Count on Day 7 — -1.78; -1.20 log10(CFU[colony forming unit]/disc+1) — p=0.0144
N/A N=60 Care Partner Assisted Intervention to Improve Oral Health of Individuals With Mild Dementia
Mild Dementia
Primary: Plaque Index — 0.55; 0.41; 0.48 Proportion of sites with plaque deposits — p=0.939
N/A N=38 Assessing Effects of a Denture Gel on Gum Abrasions
Gum Injury
Primary: Abrasion Assessment (Number) — 3.65; 4.11 number of abrasions
N/A N=26 Functionally-tailored Oral Care Intervention for Community-dwelling Older Adults With Dementia and Their Caregivers
Dementia · Cognitive Impairment
Primary: Person With Dementia: Oral Hygiene — 29.6; 37.3 percentage change in plaque scores
N/A N=16 Comparison of Two Gingival Displacement Procedures
Gingival Retraction Techniques
Primary: Percentage of Errors in Impressions Made for Indirect Restorations — 85.7; 33.3; 28.6; 44.4 percentage of impressions
N/A N=12 Dental Office Prevention Strategies for Children
Dental Plaque
Primary: Dental Plaque Levels Measures on Scale of 0-2 — 0.391 units on a scale
N/A N=290 Efficacy and Safety Study of Interproximal Cleaning Modalities on Oral Health
Gingivitis
Primary: Change From Baseline in Gingival Inflammation on a 4 Point Scale Using the Modified Gingival Index (MGI) at Day 14 — 0.10; 0.10; 0.10; 0.01 units on a scale
Phase 3 N=604 OTC Mouthpiece for Snoring
Snoring
Primary: Snoring Severity Scale — -4.1 units on a scale — p=< 0.0001
N/A N=30 Home Usability of a Nasal Lavage System in Children
Nasal Congestion · Respiratory Tract Infection · Sinusitis
Primary: Number of Participants Who Properly Used the Nasal Irrigator/Aspirator Device — 29 participants — p=0.0005
N/A N=45 Assessment of the Efficacy of the Aerodentis System
Orthodontic Treatment · Tooth Crowding · Orthodontics
Primary: Litter's Index (Change in Little's Index Mean Total Score From Baseline) — 5.7; 6.2; 0.6; 0.3 mm
N/A N=3,085 Decision Aids for the Management of Suspicious Occlusal Caries Lesions
Dental Caries
Primary: Number of Lesions That Received Invasive Treatment and the Number of Lesions Receiving Invasive Treatment That Extended Into Dentin — 603; 246; 213; 248 lesions
Phase 3 N=10 PMP-300E (Smart Watch): Portable Monitoring Device Study
Obstructive Sleep Apnea
Primary: AHI — 19.2; 19.3 events/hour — p=>0.05
N/A N=74 Home-Based Diagnosis and Management of Sleep-Related Breathing Disorders in Spinal Cord Injury
Obstructive Sleep Apnea · Hypercapnia · Spinal Cord Injury
Primary: Prevalence of Sleep-disordered Breathing in Spinal Cord-injured Adults — 40; 23; 11 participants
N/A N=31 Oral and Dermal Tolerability Clinical Study of an Experimental Denture Wipe
Denture Cleansers
Primary: Proportion of Participants Experiencing or Reporting Treatment Emergent (TE) Oral Adverse Events (AEs) on or Before 14 Days of Use — 0.039; 0.013 Proportion of…
Phase 3 N=25 Development of Clinical Method to Determination Triclosan Retention in Plaque Following Brushing.
Gingival Diseases
Primary: Plaque Index — 2.45; 2.22; 2.54; 2.56 Units on a scale — p=0.05
N/A N=62 Evaluation of Oral Hygiene Products in an In Situ Caries Model
Dental Caries
Primary: Percentage Surface Microhardness Recovery (%SMHR) of Placebo Dentifrice/Fluoride Rinse Compared to Placebo Dentifrice/No Rinse — 24.48; 8.09 % SMHR — p=<0.0001
N/A N=45 Efficacy of Three Toothpastes Using an in Situ Caries Model
Dental Caries
Primary: Percentage Surface Microhardness Recovery (SMHR) of Phyte (0% 0.425% and 0.85%) at 2 Weeks — 25.53; 26.81; 7.41; 28.88 % SMHR — p=0.7603