N/A N=5,117 Periodontal Disease Prevention Study
Periodontitis
Primary: Percentage of Participants With Tooth Loss Over 16 Year Period — 16.4; 13.8; 22.1; 16.9 percentage of participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=49 Compare Anti-inflammatory Dentifrices
Gingivitis
Primary: Gingival Index (GI) — 1.04; 1.01 units on a scale — p=<0.05
Phase 3 N=983 Prevention of Adult Caries Study (PACS)
Caries, Dental
Primary: Total Net D12FS Caries Increment (Total of Non-cavitated Lesions (D1), Cavitated Lesions (D2) and Sound Surfaces (S)) — 2.43; 2.68 weighted increment units/13 months…
N/A N=32 Risk Factors for Implant Bone Loss in Patients With Diabetes Mellitus
Diabetes
Primary: Radiographic Bone Level — 2.69; 2.54 mm
N/A N=3,345 Comparative Effectiveness of Treatments to Prevent Dental Caries
Dental Caries
Primary: Number of Participants With Arrested Dental Caries, Assessed Using a Clinical Oral Examination — 48; 53 Participants
N/A N=48 Gingival Bleeding and Von Willebrand Disease Typ 2 and 3
Gingival Bleeding · Von Willebrand Diseases
Primary: Bleeding on Probing (BOP) — 14.5; 12.3 percentage of sites
N/A N=282 Assessment of Caries Diagnosis and Caries Treatment in Dental PBRN Japan
Dental Caries
Primary: Percentage of Participants Who Indicate Surgical Intervention — 74 percentage of the dentists
N/A N=61 Trial of Toothpaste to Reduce Plaque and Inflammation
Plaque · Inflammation
Primary: Change in Oral Plaque — -1.05; -0.03 log(percentage) — p=0.001
N/A N=7,418 Comparative Effectiveness of School-based Caries Prevention
Dental Caries · Quality of Life
Primary: Proportion of Subjects With All Caries Arrested — 108; 101 Participants
N/A N=12 Dental Office Prevention Strategies for Children
Dental Plaque
Primary: Dental Plaque Levels Measures on Scale of 0-2 — 0.391 units on a scale
Phase 4 N=43 Alterations of GCF Levels of Sclerostin and DKK-1 in Postmenopausal Osteoporosis
Osteoporosis, Postmenopausal · Periodontitis
Primary: Sost Values for 6th Month — 1389.177; 1085.405; 1596.585; 2131.87 ng/ml — p=<0.01
Phase 3 N=19 Investigation of Dental Plaque and Gingival Index
Dental Plaque
Primary: Gingival Margin Plaque Index — 15.4; 12.81 Units on a scale — p=0.05
Phase 3 N=44 Antibiotic Study for Dental Implants
Periodontitis
Primary: Overall PD Reduction — 1.25; 0.66 mm
N/A N=288 Oral Health Educational Methods in Adolescence
Adolescent Behavior
Primary: Knowledge Score — 11; 13; 11; 13 score on a scale — p=0.001
Phase 4 N=57 The Efficacy of Stabilized Chlorine Dioxide Rinse as a Chemical Adjuvant for Treatment of Per-implant Mucositis
Peri-implant Mucositis
Primary: Global Probing Depth — 2.37; 2.64 mm — p=0.28
N/A N=151 Clinical Management of Anxiety and Access to Health Care
Dental Anxiety
Primary: Change in Modified Dental Anxiety Scale — 19.5; 19.6; 15.4; 17.6 units on a scale — p=<0.05
N/A N=51 Kidney and Periodontal Disease Study
Chronic Kidney Disease · Periodontal Disease
Primary: Number of Participants Completing Study Protocol — 17; 34; 14; 30 Participants
N/A N=32 Induced Gingivitis & Intra-oral Imaging
Plaque Induced Gingivitis
Primary: Change From Baseline Gingivitis at Day 14 as Measured by Non-invasive Microimaging and Gingival Index. — 0.6; 0.15 units on a scale
Phase 3 N=323 Preventing and Arresting Dental Root Surface Caries in Community-dwelling Older Adults
Dental Caries
Primary: Number of New Tooth Root Caries Lesions — 1.1; 0.43; 0.56 new carious root surfaces
Phase 3 N=60 Anticaries Effect of Xylitol,Probiotic and Chlorhexidine Mouth Rinses Among Individuals at High Risk
Cariostatic Agents · Mouthwashes
Primary: Change in Streptococcus Mutans Levels in Dental Plaque — 3.11; 0.93; 1.91; 2.23 log10CFU/g — p=0.123
Phase 3 N=23 Clinical Study to Evaluate Dental Plaque
Gingival Diseases
Primary: Dental Plaque Index — 2.48; 2.42 Units on a scale — p=0.05
Phase 2 N=38 Short-term Effect of 2% Atorvastatin Dentifrice in Periodontal Status.
Chronic Periodontitis
Primary: Change in Periodontal Inflammation Surface Area (PISA) — 638.16; 288.72 square millimeters
Phase 3 N=39 Collection of Gingival Crevicular Fluid From Periodontitis Patients
Gingival Diseases
Primary: Metabolite Associated With Inflammation (Cadaverine) — 1.119186; 0.92077 ion count — p=<0.05
N/A N=57 Silver Diamine Fluoride and Papain-Based Gel for Management of MIH-affected Molar in Paediatric Patients
Molar Incisor Hypomineralization · Dental Caries · Hypomineralization of Enamel
Primary: Clinical Outcome Based on Success After Intervention on MIH Affected Molar at 6 Months — 17; 18; 17 number of Successful MIH affected molars
N/A N=50 Nobio Clinical Study - Demineralization Prevention With a New Antibacterial Restorative Composite
Dental Caries · Denture, Partial, Removable
Primary: Mineral Loss ΔZ — 235; 774 vol% * μm]
Phase 2 N=108 Effects of Probiotics on Oral Health
Periodontal Health · Dental Plaque Accumulation
Primary: Gingival Health — 0.46; 0.18 units on a scale — p=0.015
N/A N=90 A Comparative Study of Electric Toothbrushes for the Efficacy Plaque Removal and the Effect on Plaque Accumulation and Gingivitis.
Dental Plaque Induced Gingivitis · Dental Plaque
Primary: Plaque Index — 1.07; 1.19; 1.31; 1.11 units on a scale — p=0.1561
Phase 3 N=33 The Effect of Periodontal Treatment and the Use of Dentifrice on Glycaemic Control in Diabetics
Periodontal Disease
Primary: HbA1c Levels in Blood — 9.47; 10.27 Percentage — p=0.05
Phase 4 N=49 A Clinical Study to Evaluate the Efficacy of a Range of Dental/Denture Products for Improved Oral Health in Partial Denture Wearers
Gingivitis
Primary: Mean Bleeding Index (BI) at Week 12 — 0.45; 0.76 Score on a scale — p=<0.0001
Phase 1 N=20 Fluoride Retention in the Mouth of Older Adults
Hyposalivation
Primary: Fluoride Concentration in Dental Biofilm Fluid at Baseline — 0.24; 0.22 parts per million (ppm) of fluoride — p=0.8412