Phase 2 N=117 Asacol Acute Diverticulitis(DIVA)Study
Diverticulitis
Primary: Global Symptom Score (GSS) at Week 12, Primary Efficacy Population — 7.3; 4.4; 5.9 Scores on a Scale — p=0.3781
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=107 Recurrence Following Nonoperative Management of 1st Episode of Hinchey II Diverticulitis
Diverticulitis
Primary: Primary Study Endpoint — 26; 2 Participants
Phase 3 N=590 Prevention of Recurrence of Diverticulitis
Diverticulitis
Primary: Percent of Subjects Without Recurrence of Diverticulitis — 62.2; 62.9; 52.7; 64.6 percentage of subjects — p=0.047
Phase 3 N=592 Prevention of Recurrence of Diverticulitis
Diverticulitis
Primary: Percent of Subjects Without Recurrence of Diverticulitis — 62.8; 59.2; 69.1; 67.6 percentage of subjects — p=0.778
Phase 3 N=332 PillCam™ Colon Capsule Endoscopy (PCCE) in the Visualization of the Colon
Colonic Diseases
Primary: Number of Participants With Successful Capsule Endoscopies or Standard Colonoscopies — 322; 326 participants
Phase 4 N=60 Lubiprostone, Colonic Motility and Sensation
Healthy
Primary: Colonic Compliance — 16.60; 16.50 mm Hg
N/A N=51 Evaluation of PillCam™ Colon 2 in Visualization of the Colon
Colonic Diseases · Bowel Diseases
Primary: Accuracy of Detection in Patients With Colonic Polyps - Sensitivity — 89; 100 percentage of sensiivity
Phase 2 N=192 Dose-ranging Efficacy of Polydextrose Supplement on Colonic Transit Time and Symptoms in Adults With Functional Constipation
Functional Constipation
Primary: Change in Colonic Transit Time From Baseline to Day 15 — -1.7; 4.0; 2.5; 2.6 Hours
N/A N=66 Laparoscopic Peritoneal Lavage vs Laparoscopic Sigmoidectomy in Perforated Acute Diverticulitis: a Multicenter Prospective Observational Study (STELLA Study)
Acute Diverticulitis
Primary: Short-term Morbidity — 8; 1 Participants
N/A N=804 Narrow-Band Imaging Versus Standard White Light for the Detection of Serrated Lesions in the Proximal Colon
Colon Cancer
Primary: Total Number of Serrated Lesions Proximal to the Sigmoid Colon — 204; 158; 95; 59 Serrated Lesions
N/A N=386 Efficacy of Segmental Examination Twice of the Proximal Colon on Adenoma Detection
Colonic Polyps
Primary: Difference of Adenoma Detection Rate in the Proximal Colon Among 2 Group. — 0.236; 0.331 proportion of participants
N/A N=2,379 Colorectal Polyp Clinical Decision Support Device Study
Polyp · Colorectal · Colonoscopy
Primary: Specificity and Sensitivity CDSD-unaided and CDSD-aided Endoscopist Predictions of Diminutive Polyp Histology — 90.8; 90.7; 64.7; 59.5 percentage of polyps
N/A N=26 Prevalence of Inflammatory Bowel Disease in Patients With Perianal Disease
Inflammatory Bowel Disease · Perianal Fistula · Perianal Abscess
Primary: Prevalence of Inflammation as Diagnosed by Capsule Endoscopy — 6 participants
N/A N=558 Clinical Study of Real Time Colorectal Polyp Diagnosis During Colonoscopy - the VALID Colonoscopy Study
Colorectal Neoplasm · Colonic Polyps
Primary: Rate of Accurate High Confidence Polyp Histology Predictions by the Endoscopist in the Two Groups. — 75.3; 63.1 Percent of accurate HC predictions
N/A N=7 A Colonic Tube to Improve Bowel Function in Spinal Cord Injury
Constipation · Fecal Incontinence · Spinal Cord Injury
Primary: Change in Bowel QoL — -4.17; -3.65 units on a scale
N/A N=262 Right Colon Polyp Miss Rates of Water Exchange and Carbon Dioxide Insufflation Colonoscopy
Right Colon Adenoma Miss Rate · Right Colon Hyperplastic Polyp Miss Rate
Primary: Percentage of Adenomas and Hyperplastic Polyps Missed During Initial Right Colon Examination — 18.0; 36.7 percentage of all missed polyps
N/A N=100 Cap-fitted Colonoscopy: a Randomized, Tandem Colonoscopy Study of Adenoma Miss Rates
Polyps
Primary: Number of Adenomas — 83; 89; 28; 44 First Colonoscopy number of adenomas
N/A N=7 Fluorescent Evaluation of Colorectal Anastamoses
Rectal Neoplasms · Colon Neoplasms · Diverticulitis
Primary: Evaluate the Vascular Supply of the Bowel Intra-operatively and Correlate This With Postoperative Complications Identified During Their Hospital Stay at One Week and One…
N/A N=269 Complete Histologic Resection of Adenomatous Polyps?
Adenomatous Polyps
Primary: Percent of Incompletely Resected Adenomatous Polyps — 10.1 percentage of incomplete resection
N/A N=2 Optical Frequency Domain Imaging for Assessing Colonic Polyps
Colonic Polyps
Primary: Feasibility and Sensitivity of OFDI Imaging in the Colon — 2; 1 Participants
Phase 4 N=360 Efficacy and Safety of Standard Oral Colonoscopic Preparations With or Without Neostigmine Compared to Pulse-Irrigation Colonic Lavage
Spinal Cord Injury
Primary: Quality of Bowel Preparation — 3.4; 2.5; 3.6; 7.4 units on a scale
N/A N=427 Use of a Distal Colonoscope Attachment to Increase Detection of Sessile Serrated Adenomas
Sessile Serrated Adenoma
Primary: Sessile Serrated Adenomas — 42; 59 colonoscopies
Phase 2 N=95 Testing Diet Intervention Versus Non-Diet Intervention for Management of Bowel Symptoms in Rectal Cancer Survivors
Rectal Carcinoma · Rectosigmoid Carcinoma
Primary: Bowel Function — 30.8; 29.5 MSK-BFI score on a scale (range 18-90)
N/A N=928 Safety of Endoscopic Resection of Large Colorectal Polyps: A Randomized Trial.
Colon Polyps
Primary: Number of Participants With Delayed Bleeding Complications — 16; 33 Participants
N/A N=32 Assessment of Colonic Epithelial Integrity With Mucosal Impedance
Inflammatory Bowel Diseases
Primary: Mucosal Impedance Values — 1139; 849; 891; 783 ohms
N/A N=7 Evaluation of an Endoscopic Suturing System for Tissue Apposition in Colonic Polypectomy
Polyps
Primary: Numbers of Participants With Successful Deployment of Tissue Apposition System (TAS) — 6 participants
N/A N=225 Advanced Metagenomic Analysis of Human Colonic Microbiota in Patients With Chronic GI Disorders
Irritable Bowel Syndrome · Colitis, Ulcerative · Crohn Disease
Primary: Colonic-Mucosa Associated Microbial Species Per Compiled Participants in 5 Different Arms — 40; 30; 23; 23 microbial species population
Phase 3 N=829 Efficacy and Safety of SPD476 in Maintaining Remission in Patients With Ulcerative Colitis
Ulcerative Colitis
Primary: Endoscopic Remission of Ulcerative Colitis (UC) at 6 Months — 83.7; 81.5 percent of participants
N/A N=100 Detection of Colonic Polyps Via a Large Scale Artificial Intelligence (AI) System
Colonic Polyp
Primary: Number of Additional Polyps Detected by the DEEP System in Real Time Colonoscopy — 0.89 Added polyps detected per colonoscopy
N/A N=884 Evaluation of Capsule Endoscopy With PillCam® COLON 2 in Visualization of the Colon
CRC Screening
Primary: Sensitivity and Specificity of PillCam Platform With the PillCam COLON 2 Capsule in Detecting Patients With Polyps ≥6 mm Where OC Considered as the Gold Standard…