N/A N=599 Dialysis Catheter Comparative Clinical Trial
End Stage Renal Disease
Primary: First Catheter Induced Complication — 78; 77 percentage of participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=223 A Study of Tenecteplase for Restoration of Function in Dysfunctional Hemodialysis (HD) Catheters
Dysfunctional Hemodialysis Catheters
Primary: Percentage of Participants Who Had Treatment Success With Respect to Blood Flow Rate (BFR) at Visit 1 — 34.1 Percentage of participants
Phase 3 N=150 A Study of Tenecteplase for Restoration of Function in Dysfunctional Hemodialysis Catheters
Dysfunctional Hemodialysis Catheters
Primary: Percentage of Subjects Who Had Treatment Success With Respect to Blood Flow Rate (BFR) at Visit 1 — 21.6; 5.3 percentage of success — p=0.0044
N/A N=26 Catheter System Feasibility Clinical Trial
Renal Insufficiency, Chronic
Primary: Number of Participants With Sufficient Patency for Clinical Access — 20 Participants
N/A N=80 Comparison of Tesio and LifeCath Twin Permanent Dialysis Catheters
Hemodialysis
Primary: Blood Flow Rate at First Use After Insertion — 277; 383 mL/min
N/A N=100 VectorFlow Tunneled Dialysis Catheter (TDC) Versus Palindrome TDC
Renal Failure Chronic Requiring Hemodialysis · Chronic Renal Insufficiency
Primary: Primary Patency - Intervention-free Interval (Measured in Weeks) — 89.1; 95.5; 79.4; 87.2 percentage of primary patency
N/A N=164 Arteriovenous Fistula Cannulation Practices and Dialysis Adequacy
Arteriovenous Fistula · Hemodialysis · Dialysis Adequacy
Primary: Number of Fistula Needle Direction — 72; 92 Participants
N/A N=33 Ease of Use and Blood Clotting for the Gambro Polyflux HD-C4 Big Dialyzer
Chronic Kidney Failure
Primary: Ease of Use: Priming Blood Side — 139; 13; 13; 80 Number of Dialyzers
N/A N=53 Chlorhexidine Dressings for Hemodialysis Catheter Exit Site Care: Comparative Study
Hemodialysis Catheter Infection
Primary: Bacteraemia Rate — 2; 1 episodes — p=1.00
Phase 3 N=246 A Study of Tenecteplase for Restoration of Function in Dysfunctional Central Venous Catheters
Dysfunctional Central Venous Access Catheters
Primary: Percentage of Patients Who Had Cumulative Restoration Rates of Central Venous Catheter (CVC) Function Following a Single Administration of Tenecteplase — 72.0 percentage…
Phase 3 N=100 A Study of Tenecteplase for Restoration of Function in Dysfunctional Central Venous Catheters
Dysfunctional Central Venous Access Catheters
Primary: Percentage of Patients Who Had Restoration of Central Venous Catheter (CVC) Function Following a Single Administration of Study Drug — 23.4; 60.0 percentage of…
N/A N=338 A Prospective Study of Airless Tubing in an Inpatient Acute Hemodialysis Unit in Hospitalized Patients
End Stage Renal Failure on Dialysis · Complication of Dialysis · Blood Coagulation Disorders
Primary: Clotting of Extracorporeal Dialysis Circuit — 30; 33 Clotting events — p=0.79
N/A N=212 Midlines and Thrombophlebitis
Catheter Infection · Catheter Thrombosis · Catheter Complications
Primary: Upper Extremity CR-UEVT — 7; 11 Participants
N/A N=10 Coronal Mode Ultrasound Guided Hemodialysis Cannulation: Comparison With Standard Cannulation Technique
Arteriovenous Fistula, Cannulation
Primary: Infiltration Due to Dialysis Access Cannulation — 5; 7 infiltration events
N/A N=14 Buttonhole Versus Step Ladder Cannulation in High Dose Hemodialysis
Renal Failure
Primary: Feasibility of Participant Recruitment and Site Coordination — 8; 6 Participants
N/A N=72 Hemodialysis Reliable Outflow (HeRO) Vascular Access Patency Study
Renal Failure Chronic Requiring Hemodialysis
Primary: Percentage of Patients With Primary Patency — 48.2; 47.0; 30.6; 34.8 percentage of participants patent
Phase 3 N=806 Study Assessing Safety & Effectiveness of a Catheter Lock Solution in Dialysis Patients to Prevent Bloodstream Infection
Kidney Failure, Chronic · Catheter-Related Infections
Primary: Presence of a CAC-Adjudicated Catheter-Related Bloodstream Infection (CRBSI) in Subjects Receiving Hemodialysis for the Treatment of End Stage Renal Disease (ESRD)…
N/A N=46 Breaking Down Care Process and Patient-level Barriers to Arteriovenous Access Creation Prior to Hemodialysis Initiation
Chronic Kidney Disease · Chronic Kidney Disease Requiring Chronic Dialysis
Primary: Mean Scores of a Questionnaire Evaluating Patient Confidence in Navigating Vascular Access Care Pre- to Post-program Implementation — 8.0; 8.7 score on a scale — p=0.20
N/A N=33 HeRO Graft Compared to Permanent Catheters for End Stage Renal Disease (ESRD) Patients Receiving Hemodialysis
End Stage Renal Disease (ESRD)
Primary: Mortality — 18.8; 29.4 percentage of participants who died — p=0.48
N/A N=25 Catheter Placement for Hepatic Hydrothorax
Pleural Effusion
Primary: Feasibility of Using Indwelling Tunneled Pleural Catheters for the Management of Hepatic Hydrothorax — 25 Participants
N/A N=1,229 Product Evaluation for the Effectiveness of the ClearGuard™ HD End Cap
End Stage Renal Disease (ESRD)
Primary: Positive Blood Cultures (PBCs) Per 1,000 Central Venous Catheter (CVC)-Days — 0.26; 0.59 PBCs per 1,000 CVC-days
Phase 4 N=303 Prophylactic Antimicrobial Catheter Lock
Bacteremia
Primary: Rate of Device-related Bacteremia — 30; 11 Number of infections
N/A N=88 Blood Sampling Functionality of Extended Dwell Catheters
IV Catheter-Related Infection or Complication · Vascular Access Complication · Peripheral Venous Access
Primary: Blood Sampling Functionality — 70.19; 112.9 hours
N/A N=4 Phosphodiesterase Type 5 Inhibition to Improve Endothelial Function and Vascular Remodeling in Chronic Kidney Disease and End Stage Renal Disease Patients Requiring New Arteriovenous Fistula
Improve Endothelial Function and Decrease Vascular Stenosis
Primary: Change in Baseline and 2 Week FMD/VP Measurements Between Sildenafil Group and Placebo Group — 10.8; 8.6 Change in FMD%
N/A N=103 Percutaneous Less Invasive AV Fistula for Vascular Access in ESRD
End Stage Renal Disease · AV Fistula · Fistula
Primary: Maturation Success Rate at 90 Days — 92 Participants
Phase 3 N=285 Study Comparing Lutonix AV Drug Coated Balloon vs Standard Balloon for Treatment of Dysfunctional AV Fistulae
Arteriovenous Fistula
Primary: Percentage of Participants With Target Lesion Primary Patency (TLPP) at 6 Months Post Index Procedure — 71.4; 63 Percentage of Participants — p=0.0562
N/A N=149 Hub Cleansing to Prevent Hub Infection
Bacteremia
Primary: Number of Central Venous Catheter Hubs With Internal Contamination — 42; 18; 39; 14 contaminated hubs
N/A N=12 Molecule Removal and Ease of Use: A Comparison of Two Different Dialyzers
Chronic Kidney Disease
Primary: Comparison of Urea Removal Under Conditions of Routine Hemodialysis. — 1.64; 1.61; 1.42; 1.40 ratio
N/A N=15 Confirmatory Study to Assess the V Needle in End-Stage Renal Disease Patients During In-Clinic Hemodialysis
End Stage Renal Disease
Primary: Percentage of Successful Hemodialysis Sessions — 100; 98.9 percentage of successful sessions — p=.008
N/A N=165 Passive Disinfection Cap Compliance Study
Infection, Hospital
Primary: Disinfecting Barrier Cap Compliance — 98.43 percentage of connector with compliance