Phase 2 N=181 Effect of LIK066 on Body Weight in Patients With Elevated Body Mass Index
Elevated Body Mass Index
Primary: Part 1: Percent Change in Body Weight From Baseline to Week 12 — -5.51; 0.19; -6.55; 0.29 percent change — p=<0.001
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=18 Effect of Weight and/or Obesity on Ethambutol Drug Concentrations
Obesity · Tuberculosis
Primary: Total Clearance of Ethambutol — 80.8 L/h
N/A N=30 Study of Impact of Behavioral Intervention- Exercise, Nutrition, Education- on Body Mass Index (BMI)
Obesity
Primary: Change in BMI (Body Mass Index) — -0.74; 1.33; -0.18; 0.98 kg/m^2 — p=0.03
Phase 4 N=32 Oral Contraceptives and Body Mass Index
Body Weight · Contraceptive Usage
Primary: LNG Steady State at Baseline and Then Post-randomization — 3.82; 3.13; 3.01; 3.58 ng/mL
N/A N=645 Brief Motivational Interviewing to Reduce Child Body Mass Index
Childhood Obesity
Primary: Child BMI Percentile — 90.31; 88.1; 87.1 BMI Percentile
N/A N=5,392 Impact of Body Weight on the Immediate Health of the Pediatric Population
Childhood Obesity
Primary: Diagnosis of Infectious Disease — 900; 1067 Participants — p=.026
N/A N=18 The Effects of Chiropractic in a Population With High Central Adiposity
Abdominal Obesity
Primary: Proportion of Potential Participants Who Are Eligible. — 0.95 Proportion
Phase 3 N=50 Safety and Efficacy of Adjustable Gastric Band Operations for Patients With Body Mass Index (BMI) Between 30-40 kg/m2
Obesity
Primary: To Determine Percent of Excess Weight Loss (%EWL) After Laparoscopic Adjustable Gastric Banding Surgery — 51.74 percentage of excess weight loss
N/A N=76 Pediatric Quality of Life Among Population With Body Mass Index (BMI) Greater Than or Equal to 85%
Pediatric Obesity
Primary: Change in Child Self-report Health Related Quality of Life Scores After Intervention: Total, Physical and Psychosocial (Presented in This Order) — 7.8; -0.9; 9.1; -0.3…
N/A N=30 Effects of Body Mass Index on the Hyperemic Response to Regadenoson
Obesity · Endothelial Dysfunction · Decreased Vascular Flow
Primary: Myocardial Perfusion Reserve Measured by Quantitative Perfusion MRI (Ratio of Myocardial Blood Flow During Stress Over Myocardial Blood Flow at Rest) — 2.25; 2.44 ratio…
N/A N=47 Healthy Bodies, Healthy Kids
Child Mental Disorders · Obesity · Metabolic Syndrome
Primary: DEXA-measured Adiposity — 0.76; -0.43; -2.79 kilograms — p=0.01
Phase 2 N=18 PEEP as Rescue Therapy for Asthmatics With Elevated BMI
Asthma
Primary: Central and Peripheral Elastance — 391; 461; 587; 334 cmH2O/L
N/A N=29 Clinical Effectiveness of Body Fat Distribution Imaging in Real-World Practice: The BODY-REAL Study
Overweight and Obesity · PreDiabetes · Type 2 Diabetes
Primary: Change in BMI — 0.43; 0; 4.4; 0 kg/m2 — p=0.2
N/A N=8,584 Low Indexes of Metabolism - Information to Teams (LIMIT)
Weight Loss · Thinness · Malnutrition
Primary: Death From Any Cause — 285; 245 Participants
N/A N=50 Bariatric Surgery for Morbid Obesity
Obesity · Morbid Obesity
Primary: Size of Adipocytes — 73.4; 99.0; 103.0 µm
N/A N=281 Maternal-Offspring Metabolics:Family Intervention Trial
Pregnancy · Weight Gain
Primary: Gestational Weight Gain (GWG) — 12; 10 kg — p=0.01
Phase 1 N=22 PED NEONAT 20-000599 Fetal Body Composition
IUGR · Gestational Diabetes · Pregnancy Related
Primary: Maternal Visceral Adipose Tissue Volume — 97593; 169626; 96787 mm3
N/A N=46 Targeting Body Image Among Women of Higher Body Weight
Obesity · Overweight · Body Image
Primary: EDE-Q Weight and Shape Concern — 3; 6; 0; 3 Participants
N/A N=72 Determinants of Gestational Weight Gain in Obese Pregnant Women
Energy Intake · Energy Expenditure
Primary: Energy Intake — 2908; 2698; 2581 kilocalories per day
N/A N=271 Weight Discrimination and Poor Cardiovascular Health
Obesity
Primary: Negative Affect — 1.43; 1.29 score on a scale — p=.007
N/A N=57 Insulin-sensitive Obesity: Lessons From Longitudinal Data
Insulin Sensitivity/Resistance · Obesity
Primary: Insulin Sensitivity — 0.0105; -0.0076; 0.0041 micro mol/min/Kg/mU/L/year
N/A N=441 Choosing Healthy Options in College Environments and Settings
Obesity
Primary: Change in Body Mass Index (BMI) — 26.2; 26.0 kg/m2 — p=0.707
Phase 4 N=371 Body Weight Effects on Glucophage's Efficacy in Chinese Diagnosed T2DM Patients
Type 2 Diabetes Mellitus
Primary: Mean Change From Baseline at Week 16 (95% Confidence Interval) in Glycosated Hemoglobin A1c (HbA1c) (Last Observation Carried Forward) - Full Analysis Set (FAS) — -1.95…
N/A N=150 Generation of Prediction Equations for BIA of the Elderly
Healthy Elderly
Primary: Total Body Water — 1.85 liter
N/A N=102 Metformin in Overweight Type 2 Diabetes Mellitus
Obesity · Type 2 Diabetes Mellitus
Primary: Change in Weight From Baseline at 12 Months or More — -8.37 Kg — p=<0.05
N/A N=105 Behavioral Weight Loss and Stigma Reduction
Obesity
Primary: Percent Weight Change at Week 72 — -7.16; -5.19 percent weight change — p=0.14
Phase 2 N=22 Fecal Microbiota Transplantation for the Treatment of Obesity
Obesity
Primary: Adverse Event Frequency — 11; 11; 1; 0 Participants
Phase 2 N=20 Study to Evaluate ARD-101 in Adults With Obesity
Obesity
Primary: Relative Change in Body Weight (%) — -0.33; 0.38 Percentage of body weight change
N/A N=10 Measurement of Body Fat in Infants
Brown Adipose Tissue · Body Composition
Primary: Whole Body Fat Mass — 20.8 percentage of fat mass
N/A N=24 Growth Hormone as a Determinant of Weight Regulation
Obesity
Primary: 24 Hour Average Plasma Growth Hormone Concentration — 0.4; 1.2; 4.1 ng/mL