N/A N=21 Cerebral Palsy: Ankle Foot Orthoses - Footwear Combinations
Cerebral Palsy (CP)
Primary: Change in Baseline Gait Profile Score (GPS) at 3 Months-individual Lower Extremity Joint Kinematics — 0.41; -0.48 units on a scale — p=0.36
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=39 Bracing and Strengthening for Posterior Tibial Tendon Dysfunction
Posterior Tibial Tendon Dysfunction
Primary: Foot Function Index(FFI) — 16.0; 12.7; 8.1; 8.3 units on a scale
N/A N=23 Weightbearing Assessment of Tarsal Instability
Adult-acquired Flatfoot Disorder (AAFD)
Primary: Change in Joint Motion Between Touch-down Bearing Navicular and Full-weight Bearing Navicular — 3.56; 4.36; -0.1666; -0.170 mm
N/A N=60 Metatarsal Phalangeal Joint Deformity Progression - R01
Diabetes Mellitus (DM)
Primary: Change in Metatarsal Phalangeal Joint Angle (Degrees) in People With Diabetes From Baseline and at a 3-year Period — 0.8; -0.1 degrees
N/A N=80 Polyurethane Foam on the Heel for Prevention in Children
Flat Foot · Pressure Ulcer
Primary: Heel Pressure Sores (Numbers of Participants With Heel Pressure Sores) — 17; 21 Participants
N/A N=12 Novel Dynamic Foot Abduction Bar for Treatment of Clubfoot
Clubfoot
Primary: Recruitment of Patients for a Prospective Trial Comparing Clubfoot Brace Types — 59; 17 Participants
N/A N=6 Gait in Children With Down Syndrome While Wearing Orthoses
Down Syndrome
Primary: Step Width — 10.4 cm
N/A N=85 Effectiveness of Core Stability Exercises on Foot Posture, Function and Limb Alignment in Flexible Flat Feet Patients
Flexible Flatfoot
Primary: Staheli Plantar Arch Index (SPAI) — -0.18; -0.03; -0.138; -0.036 Millimeters (mm) — p=<0.001
Phase 2 N=186 Dysport in Hallux Abducto Valgus (HAV) Phase IIa
Hallux Abducto Valgus
Primary: Least Square (LS) Mean Change From Baseline in the Daily Numeric Pain Rating Scale (NPRS) Score at Week 8 — -2.04; -1.71; -2.40 units on a scale — p=0.7669
N/A N=139 Duration of Brace Wear in Clubfoot Treatment - A Prospective Randomized Trial
Isolated Clubfoot
Primary: Kaplan-Meier Recurrence-Free Survival Probability for Clubfoot Affected Limbs — 0.81; 0.65 survival probability — p=0.03
N/A N=11 Do Rocker Bottom Shoes and Ankle-Foot Orthoses Reduce Pain and Improve Mobility for Ankle Osteoarthritis Patients
Ankle Osteoarthritis · Healthy Ankles
Primary: Daily Step Count (# Steps) — 3453; 2399; 3453; 2745 steps
N/A N=48 Prospective Subtalar, Double, or Triple Arthrodesis Study With CCS Screws
Post-traumatic Osteoarthritis, Unspecified Ankle and Foot · Localized, Primary Osteoarthritis of the Ankle and/or Foot
Primary: Number of Participants With Intraoperative Complications — 0 Participants
N/A N=56 AMPLEX Ankle Fusion and Hindfoot
Arthrodesis Surgery Involving the Hindfoot or Ankle
Primary: Proportion of Subjects Who Met All Five Criteria for Subject Performance Composite (SPC) Endpoint — 79.5; 35.3 percentage of subjects
N/A N=107 Study of an Orthotic Designed to Equalize Leg Lengths for Patients With Injuries Managed in Walking Boots
Joint Pain · Trouble Balancing
Primary: Patient Reported Balance — 3.0; 2.1 units on a scale
N/A N=67 Outcomes of Compliance With Brace Wear in Clubfoot
Clubfoot
Primary: Wear Rate Percentage (Number of Hours Per Day Brace Was Worn Out of the Recommended 24 Hours) — 91.7; NA; NA; 86.8 percentage of time worn
Phase 4 N=11 Assessment of Gait After Dysport Treatment
Equinovarus; Acquired
Primary: Self-Selected Velocity (SSV) — 0.41; .48; 0.48; 0.52 m/s
N/A N=57 Efficacy of Leg Casts With Heel Off-loaded in Children
Orthopedic Disorders
Primary: Pain Score on the "Numeric Rating Scale" or "Visual Rating Scale" or "Face, Legs Activity Cry Consolability" According to Age Group — 4.4; 3.9 units on a scale
Phase 3 N=216 Dysport® Pediatric Lower Limb Spasticity Follow-on Study
Cerebral Palsy · Muscle Spasticity · Children
Primary: Number of Subjects With Treatment Emergent Adverse Events (TEAEs) Reported in the Double Blind (DB) + Open Label (OL) Period. — 177; 5; 91; 151 participants
N/A N=50 Ankle Foot Orthosis Comparative Effect
Foot Injuries and Disorders
Primary: PROMIS Patient Reported Outcomes for Physical Function — 44.78; 45.02 score on a scale
Phase 3 N=120 Study of GSK1358820 In Patients With Post-Stroke Lower Limb Spasticity
Post-Stroke Spasticity · Cerebrovascular Accident
Primary: Area Under the Curve (AUC) for the Change From Baseline in Modified Ashworth Scale (MAS) Ankle Score to the End of the DB Phase (Week 12) — -8.513; -5.085 Score*week…
N/A N=45 Ankle Robot to Reduce Foot Drop in Stroke
Stroke · Foot Drop
Primary: Gait Velocity During Self-selected Overground Walking — 0.48; 0.48; 0.54; 0.56 CM/SEC
N/A N=495 WalkAide Compared to Ankle-Foot Orthosis (AFO) in Stroke Patients
Stroke
Primary: Gait Velocity — .682; .635 m/sec
N/A N=40 E-Stim and Achilles Tendon Repair Study
Achilles Tendon Rupture
Primary: Reduce Calf Muscle Atrophy — 859.8; 874.9; 1450.4; 1634.9 mm^2
N/A N=65 Validation of Plantar Orthoses for Abnormal Plantar Arch Using a New Non-invasive Clinical Imaging System
Flat Feet · High Arched Foot
Primary: Change From Baseline in Body's Postural Symmetry Index(SSIM Gray) at 2 Months — -0.031; 0.010 score on a scale
Phase 2 N=54 Endermotherapy for Children With Developmental Disabilities
Cerebral Palsy · Developmental Delay
Primary: Ankle Passive Range of Motion — 8.3; 10.4 degree
N/A N=22 Plantarflexion Reduces Urgency and Peak Detrusor Pressure in Patients With Detrusor Overactivity
Overactive Detrusor
Primary: Mean Peak Detrusor Pressures — 58; 31 cm H2O
Phase 2 N=20 Efficacy of Teriparatide in Diabetic Inactive Charcot Neuroarthropathy of Foot
Diabetic Neuropathic Arthropathy
Primary: SUV Max on PET/CT Scan at 12 Months — 26.1; 22.9 g/ml
N/A N=43 Comparison of Braces for Treatment of Sever's Disease
Sever's Disease
Primary: Changes in the Oxford Ankle Foot Questionnaire for Children (OxAFQ-C) Scores — 0.27; 0.22; 0.19; 0.18 score on a scale
Phase 2 N=30 Micro-mobile Foot Compression and Diabetic Foot
Diabetes · PAD · Lower Extremity Edema
Primary: Change in Balance From Baseline to 4 Weeks — 0.94; 0.76 cm
N/A N=11 Orthotics in Ambulatory Cerebral Palsy
Cerebral Palsy
Primary: Walking Activity Levels — 4660; 4897 average total strides/day — p=< 0.05